The object is to acquire electroencephalogram of high resolution with fewer number of electrodes than usual. An electroencephalogram measurement apparatus comprising: a plurality of electrodes 110 attached on the scalp of a subject for acquisition of electroencephalogram signals of the subject; and an electroencephalogram generation unit 150 for generating an electroencephalograms at locations of the scalp where the electrodes are attached and electroencephalograms at locations of the scalp where the electrodes are not attached.

A method of processing EEC signals received from a plurality electrodes. The method comprises processing the EEC signals to determine a modulation index value for each electrode, determining one or more electrodes that have a modulation index value above a threshold level observed during ictal activity, and using the determined one or more electrodes, to identify one or more possible regions of interest corresponding to seizure zones of a subject's brain.

Described is a system for automatic adjustment of neurostimulation. The system controls stimulation of specific neural regions through a neural device positioned on a human subject, while simultaneously performing recordings from the neural device using a targeted arrangement of stimulating electrodes and distinct types of recording electrodes of the neural device. Stimulation of the specific neural regions is adjusted in real-time based on the recordings from the neural device.

In certain embodiments, a neural probe comprises a substrate comprising elongated shanks for penetrating neural tissue, each comprising a proximal end and a distal end; at least one optical source integral to the neural probe for illuminating the neural tissue; and microelectrodes located proximate the distal end of the elongated shanks for monitoring neuronal activity. In certain embodiments, a method of monitoring neuronal activity comprises implanting the neural probe into a test subject such that the elongated shanks protrude into neural tissue of the test subject; illuminating the neural tissue with the at least one optical source; and measuring neuronal activity in response to illuminating the neural tissue. In certain embodiments, a device comprises a semiconductor chip; at least one optical source integral to the semiconductor chip; and sensor elements integral to the semiconductor chip for collecting data responsive to light emitted from the at least one optical source.

The present invention relates generally to an ophthalmic device capable of monitoring neural frequencies and correlating the measured frequencies them to specific brain activity/functions. In some embodiments, profiles specific to the user of the ophthalmic device can be pre-programmed to tailor a brain activity/function profiles according to a user. Based on the determined brain activity/function from the correlation, a signal may be generated to provide feedback to the user. The signal may be transmitted to the user in one or more form. For example, the signal may be outputted to a wireless device in wireless communication with the ophthalmic device, and/or through an audible signal projected by an acoustic element, and/or a visual signal projected using a photon emitter, both which may be included in the ophthalmic device.

The present disclosure describes system and methods for detecting and amplifying weak magnetic fields generated by anatomical structures. The disclosure describes an implantable magnetic reporter system. The magnetic reporter system includes a magnetic reporter. The magnetic reporter includes a platform coupled to a support structure by a plurality of torsional flexures. A magnet is disposed on the platform, and the magnet and platform rotate when exposed to a magnetic field. The rotation of the magnet generates a stronger magnet field that is detectable external to the patient.

A method of extracting complex impedance from selected volumes of the material under test (MUT) combined with various embodiments of electrode sensor arrays. Configurations of linear and planar electrode arrays provide measured data of complex impedance of selected volumes, or voxels, of the MUT, which then can be used to extract the impedance of selected sub-volumes or sub-voxels of the MUT through application of circuit theory. The complex impedance characteristics of the sub-voxels may be used to identify variations in the properties of the various sub-voxels of the MUT, or be correlated to physical properties of the MUT using electromagnetic impedance tomography and/or spectroscopy.

A lightweight, disposable and substantially radiolucent electrode or sensor assembly for that universally connects to separate, non-integrated electrodes or sensors for the monitoring of the physiological parameters of a live subject wherein the electrode assembly is comprised of one or more radiolucent electrical connectors for connecting the electrode assembly to the sensors. The present invention also discloses a method of positioning the electrode assembly on a patient whose physiological signs are being monitored such that access to the patient's chest is substantially unimpeded so as not to obstruct the electromagnetic imaging of the patient's chest, the application of defibrillation paddles or surgical procedures that require access to the chest area.

A bioelectrode including a plate, a first electrode disposed on a first side of the plate, and a second electrode disposed on the first side of the plate and separate from the first electrode. The bioelectrode further includes a first guard portion disposed on a second side of the plate, a second guard portion disposed on the second side of the plate and separate from the first guard portion, and a preamplifier configured to output a voltage signal based on a biosignal measured between the first electrode and the second electrode.

The present disclosure provides methods for identifying non-penetrating brain injury in a subject, as well as methods for classifying a subject that received a hit to the body that transmitted an impulsive force to the brain as either having a non-penetrating brain injury or not, by analyzing one or more components of frequency-following response (FFR) following administration of an acoustic stimulus to the subject. In addition, the present disclosure provides methods for assessing a subject's recovery from a non-penetrating brain injury. Also disclosed herein are processes and systems for automatically generating acoustic stimuli and processing brain response data to identify non-penetrating brain injuries in subjects.