A method of monitoring and/or diagnosing an autoregulation mechanism of blood pressure of a living being using an ECG signal includes recording the ECG signal of the living being, and the recording a pulse wave curve synchronously with the recording of the ECG signal. Heart rate intervals are determined from the ECG signal. A pulse wave transit time is determined for each heart rate interval from the pulse wave curve. A plurality of significant changes in the pulse wave transit times are determined according to a specified criterion. One respective heart rate interval correlated in time with each significant change in the pulse wave transit times is selected as an anchor point. A determined limited number of temporally successive heart rate intervals temporally before and/or after each anchor point are selected to thus generate a limited sequence of heart rate intervals for each anchor point. The method further includes averaging the corresponding heart rate intervals of each sequence of a respective anchor point over all sequences of the anchor points.

An implantable monitoring device is disclosed for monitoring a patient's heart rate variability over time. The device includes a cardiac electrogram amplifier, a sensing electrode coupled to an input of the amplifier, timing circuitry, processing circuitry and a memory. The timing circuitry defines successive shorter time periods during each monitoring period. The processing circuitry relies upon electrogram activity that occurs during rest periods that extend as long as T1, all of which is stored into memory. Active periods are not considered as part of the heart rate variability calculation. The processing circuitry calculates median intervals between depolarizations of the patient's heart sensed by the amplifier during the shorter time periods and calculates a standard deviation of the median intervals during T2, a longer monitoring period.

Long-term electrocardiographic and physiological monitoring over a period lasting up to several years in duration can be provided through a continuously-recording subcutaneous insertable cardiac monitor (ICM). The sensing circuitry and the physical layout of the electrodes are specifically optimized to capture electrical signals from the propagation of low amplitude, relatively low frequency content cardiac action potentials, particularly the P-waves that are generated during atrial activation. In general, the ICM is intended to be implanted centrally and positioned axially and slightly to either the left or right of the sternal midline in the parasternal region of the chest. Additionally, the ICM includes an ECG sensing circuit that measures raw cutaneous electrical signals and performs signal processing prior to outputting the processed signals for sampling and storage.

Long-term electrocardiographic and physiological monitoring over a period lasting up to several years in duration can be provided through a continuously-recording subcutaneous insertable cardiac monitor (ICM). The sensing circuitry and the physical layout of the electrodes are specifically optimized to capture electrical signals from the propagation of low amplitude, relatively low frequency content cardiac action potentials, particularly the P-waves that are generated during atrial activation. The ICM is intended to be implanted centrally and positioned axially and slightly to either the left or right of the sternal midline in the parasternal region of the chest, with at least one of the ECG sensing electrodes of the ICM being disposed for being positioned in a region overlying the sternum or adjacent to the sternum and the other of the electrodes also being disposed for being positioned over the sternum or adjacent to the sternum of on the patient's chest.

A system and method for facilitating a cardiac rhythm disorder diagnosis with the aid of a digital computer is provided. A plurality of R-wave peaks are identified in a set of ECG data and a difference between recording times of successive pairs of the R-wave peaks are calculated as R-R intervals. A heart rate associated with each time difference is determined. An R-R interval plot of the ECG data is formed. The R-R intervals are plotted along an x-axis of the R-R interval plot and the heart rates associated with the R-R intervals are plotted along a y-axis of the R-R interval plot. A diagnostic composite plot is generated, including the R-R interval plot, a near field view of a portion of the ECG data, and an intermediate field view of a different portion of the ECG data for diagnosis of a cardiac event.

Systems, methods and devices for reducing noise in health monitoring including monitoring systems, methods and/or devices receiving a health signal and/or having at least one electrode and/or sensor for health monitoring.

A monitor recorder-implemented method for electrocardiography data compression and an electrocardiography monitor recorder with integral data compression are provided. A series of data items are obtained, each of the data items associated with a magnitude of an ECG signal sensed by a monitor recorder. A range is set for an initial one of the data items in the series. Each of the data items remaining in the series is processed, including: obtaining an estimation of probabilities of the data items appearing next to that data item in the series; dividing the further range into sub-ranges, each sub-range representing a fraction of the further range proportional to the probabilities of the next data items; selecting the sub-range corresponding to the data item next to that data item in the series; and representing the next data item by the selected sub-range in a non-volatile memory.

A computer-based system for monitoring the heart muscle function of a patient, with contextual oversight, includes a sensor array for collecting physiological and environmental data that are pertinent to the patient. A context register is also included which contains periodically updated patient-specific data that establishes a relevant contextual oversight capability for the system. In operation, a computer identifies anomalies in the physical data and detects aberrations in the environmental data. These anomalies and aberrations are then interactively evaluated together, relative to the contextual oversight capability, to determine whether clinical intervention for the patient is warranted.

A method and system for visualization of electrophysiology information sensed by electrodes on a catheter, includes recording times of electrode signal acquisition, designating a reference electrode signal acquisition, assigning a relative time to each recorded time of electrode signal acquisition relative to the reference electrode signal acquisition, identifying the electrodes with signal acquisition, correlating assigned relative times to identified electrodes to generate a sequence of electrode signal acquisitions, and generating a visual representation of the sequence of electrode signal acquisitions generating a visual representation with a graphical image of the electrodes, wherein individual electrodes are visually marked to represent the sequence of electrode signal acquisitions.

A method includes receiving an electrocardiogram (ECG) measured at a given location over a portion of a heart. Based on the measured ECG, a rhythmic pattern is identified over a given time-interval. The rhythmic pattern corresponds to a relation between a present cardiac cycle length and a preceding cardiac cycle length. Based on the identified rhythmic pattern, a classification of the location as either showing regular pattern or showing arrhythmia is determined. The location is graphically encoded according to the classification. The graphically encoded location is overlaid on an anatomical map of the portion of a heart.