Patent classifications
G01N2015/1062
Blood analysis method, control device and blood cell analyzer
The present disclosure provided a blood cell analyzer, a control device and a blood analysis method thereof. In the method, a first reagent is mixed with a sample to obtain a first testing sample, and then a second reagent is mixed with the first testing sample for a further reaction to get a second testing sample for basophil classification and/or HGB measurement. A blood sample may be tested in one reaction cell through time-division multiplexing technology to obtain four groups leukocytes classification result and HGB result by single detection channel. Thus, the structure of the analyzer may be greatly simplified on the premise of guaranteeing the performance of the analyzer, the size and cost of the analyzer may reduce and a performance-price ratio of the analyzer may increase.
Slurry analysis system using flow restriction
A slurry analysis system (14) for estimating a first characteristic of a slurry (12) having a plurality of particles (18) suspended in a dispersion medium (20) can include a flow restriction assembly (40); a sensor assembly (43) that senses a sensed condition of the slurry (12) as it flows through the flow restriction assembly (40); and a control and analysis system (26) that estimates the first characteristic of the slurry (12) based on the sensed condition. Further, the control and analysis system (26) can select a selected clogging behavior using the sensed condition, and estimate the first characteristic based on the selected clogging behavior.
METHODS AND COMPOSITIONS FOR IMPROVING KIDNEY FUNCTION IN PATIENTS WITH HEPATORENAL SYNDROME
The principles and embodiments of the present disclosure relate to methods for using terlipressin to treat a patient having impaired renal function associated with liver disease. A method of improving kidney function in an adult patient with hepatorenal syndrome with rapid reduction in kidney function may include determining the patient's acute-on-chronic liver failure (ACLF) grade and baseline serum creatinine level; obtaining a baseline oxygenation saturation (SpO.sub.2) of the patient; administering a dose of terlipressin acetate to the patient by intravenous (IV) injection; and monitoring the patient's oxygenation saturation with pulse oximetry.
ELECTRICAL SENSING, TRACKING, AND ACTUATION OF DROPLETS
Devices, techniques, and processes are disclosed that use electrical impedance to detect of the presence and contents of droplets including cells, nucleic acids, proteins, or solute concentrations in an array of retrievable, trackable, trapped droplets in a fluidic system. Electrodes may be positioned underneath individual droplet traps in a microchannel to assay droplet contents and/or actuating droplets for the release of the droplets from corresponding traps. The disclosed technology may be used for detection of the results of solvent extraction processes including time-dependent quantification of metal ion concentration in the aqueous and organic phases, for wastewater treatment, heavy metal detection, pharmaceutical industry, and/or biotechnology, or for environmental monitoring of wastewater for toxic metal, monitoring of biological cell viability and proliferation, monitoring of extraction processes used in heavy metal mining, monitoring of extraction processes used in nuclear fuel processing, monitoring kinetics of enzyme processes, and/or assessing pharmacodynamics and drug efficacy.
PRESERVATION LIQUID FOR CALCIUM OXALATE DIHYDRATE CRYSTALS AND PRESERVATION METHOD
The present disclosure provides a preservation liquid for calcium oxalate dihydrate crystals, which is a solution containing an anionic surfactant or a non-ionic surfactant. Also provided is a method for preserving calcium oxalate dihydrate crystals, the method including preserving calcium oxalate dihydrate crystals in a solution containing an anionic surfactant or a non-ionic surfactant.
BLOOD ANALYSIS METHOD, CONTROL DEVICE AND BLOOD CELL ANALYZER
The present disclosure provided a blood cell analyzer, a control device and a blood analysis method thereof. In the method, a first reagent is mixed with a sample to obtain a first testing sample, and then a second reagent is mixed with the first testing sample for a further reaction to get a second testing sample for basophil classification and/or HGB measurement. A blood sample may be tested in one reaction cell through time-division multiplexing technology to obtain four groups leukocytes classification result and HGB result by single detection channel. Thus, the structure of the analyzer may be greatly simplified on the premise of guaranteeing the performance of the analyzer, the size and cost of the analyzer may reduce and a performance-price ratio of the analyzer may increase.
SYSTEMS AND METHODS FOR COUNTING PARTICLES
Systems and methods are provided for counting particles in a fluid flow. In an aspect, coordinates of particles are obtained from video data of particles in a fluid, the video data made up of a sequence of image frames. The particle positions are linked in each pair of consecutive image frames of the video data. The linked particle positions are used to calculate particle trajectories through sequential image frames of the video data, and the particles are counted based on the particle trajectory. In another aspect, the particle positons within each image frame are transformed to estimated positions within a common coordinate frame. The estimated particle positions of a particle are grouped into a cluster center, and the particle count is calculated based on the cluster centers.
GAS DETECTION SYSTEM FOR GYNECOLOGICAL DISEASE DETECTION AND DETECTION METHOD USING THE SAME
A gas detection system for gynecological disease detection and a detection method using the same are provided. The gas detection system is configured to detect an analyte from a female vagina and includes: a main body, a sleeve, a detection module, a pump, and a control module. The main body includes a body portion and a head portion having an intake channel. The body portion includes a detection chamber and an exhaust channel. The detection module includes at least one sensor configured to detect at least one target of the analyte and produce at least one detection signal. The pump is communicated with the detection chamber and the exhaust channel. The control module includes a processing unit and a first communication unit. The processing unit receives the at least one detection signal and controls the first communication unit to send the at least one detection signal.
Electrical sensing, tracking, and actuation of droplets
Devices, techniques, and processes are disclosed that use electrical impedance to detect of the presence and contents of droplets including cells, nucleic acids, proteins, or solute concentrations in an array of retrievable, trackable, trapped droplets in a fluidic system. Electrodes may be positioned underneath individual droplet traps in a microchannel to assay droplet contents and/or actuating droplets for the release of the droplets from corresponding traps. The disclosed technology may be used for detection of the results of solvent extraction processes including time-dependent quantification of metal ion concentration in the aqueous and organic phases, for wastewater treatment, heavy metal detection, pharmaceutical industry, and/or biotechnology, or for environmental monitoring of wastewater for toxic metal, monitoring of biological cell viability and proliferation, monitoring of extraction processes used in heavy metal mining, monitoring of extraction processes used in nuclear fuel processing, monitoring kinetics of enzyme processes, and/or assessing pharmacodynamics and drug efficacy.
Devices, cartridges, and sensors for analyzing a biological sample
Described herein are cartridges and devices for operating said cartridges for analyzing a biological sample, such as a blood or saliva sample. Also described herein is an impedance sensor for analyzing a biological sample. Further described herein are methods of determining a cell count or detecting an analyte in a biological sample, which can include transporting the biological sample through a sensor comprising a channel or pore; applying an electrical current or voltage to the channel or pore; detecting an impedance within the channel or pore; and determining a cell count or detecting the analyte based on the detected impedance. Also described herein is an electrowetting electrode array that is configured to transport aqueous solutions using low voltage, such as about 50 volts or less. Further described herein are methods of transporting an aqueous liquid using electrowetting electrodes.