Patent classifications
G01N2015/1062
Blood analysis method, control device and blood cell analyzer
The present disclosure provided a blood cell analyzer, a control device and a blood analysis method thereof. In the method, a first reagent is mixed with a sample to obtain a first testing sample, and then a second reagent is mixed with the first testing sample for a further reaction to get a second testing sample for basophil classification and/or HGB measurement. A blood sample may be tested in one reaction cell through time-division multiplexing technology to obtain four groups leukocytes classification result and HGB result by single detection channel. Thus, the structure of the analyzer may be greatly simplified on the premise of guaranteeing the performance of the analyzer, the size and cost of the analyzer may reduce and a performance-price ratio of the analyzer may increase.
BLOOD ANALYSIS METHOD, CONTROL DEVICE AND BLOOD CELL ANALYZER
The present disclosure provided a blood cell analyzer, a control device and a blood analysis method thereof. In the method, a first reagent is mixed with a sample to obtain a first testing sample, and then a second reagent is mixed with the first testing sample for a further reaction to get a second testing sample for basophil classification and/or HGB measurement. A blood sample may be tested in one reaction cell through time-division multiplexing technology to obtain four groups leukocytes classification result and HGB result by single detection channel. Thus, the structure of the analyzer may be greatly simplified on the premise of guaranteeing the performance of the analyzer, the size and cost of the analyzer may reduce and a performance-price ratio of the analyzer may increase.
METHODS AND SYSTEMS FOR DETERMINING TARGET SENSITIVITY TO A THERAPEUTIC FORMULA
Systems and methods are disclosed herein for determining the sensitivity of a target to a therapeutic formula. The systems include a measurement device for measuring properties of a target sample fluid housed within a cartridge (the cartridge having at least one test compartment and at least one control compartment). Methods can include determining the concentration of the target suspended in a target sample fluid and placing the target sample fluid into at least one test compartment comprising a first therapeutic formula. The system, via a processor, measures the properties of the sample fluid, compares the measured properties to a threshold property, determines the sensitivity of a target species to a therapeutic formula, and presents an indicator of the target sensitivity to an end user. In some embodiments, the sensitivity data can be stored to a database for later use by an adaptive machine learning tool.
CELL ANALYZER, METHOD FOR CLASSIFYING WHITE BLOOD CELL BASED ON IMPEDANCE METHOD, AND COMPUTER-READABLE STORAGE MEDIUM
Disclosed are a cell analyzer and a method for classifying white blood cells based on an impedance method. The method includes: adding a sample to be analyzed to a white blood cell counting chamber; adding a hemolytic agent to the white blood cell counting chamber at least once; controlling the temperature of the liquid in the white blood cell counting pool to be within a predetermined range; and analyzing the liquid in the white blood cell counting chamber to classify white blood cells into at least four classifications and counting.
METHOD FOR CLASSIFYING AND COUNTING WHITE BLOOD CELLS, HEMATOLOGY ANALYZER, AND COMPUTER READABLE STORAGE MEDIUM
The disclosure provides white blood cell classifying and counting method, blood analyzer, and computer readable storage medium. The method includes: obtaining a first histogram of white blood cells in a blood sample treated by a first hemolytic agent and a second histogram of white blood cells in the blood sample treated by a second hemolytic agent, wherein a ghost value in the second histogram is smaller than a ghost value in the first histogram, and the ghost value in the second histogram is smaller than a threshold value; determining peak type of the second histogram; when the peak type is double-peak, performing classification and counting of white blood cells using the second histogram; and when the peak type is single-peak, performing classification and counting of white blood cells by combining a classification result and a counting result of the second histogram and a classification result of the first histogram.
SAMPLE ANALYZING METHOD AND SAMPLE ANALYZER
Disclosed are a sample analyzing method and a sample analyzer for measuring red blood cells and platelets. The method includes: preparing a first test sample solution containing a blood sample and a diluent; using an impedance method to acquire a first measurement result of red blood cells and platelets; when the first measurement result indicates that the blood sample is abnormal, preparing a second test sample solution containing the blood sample and a diluent or preparing a second test sample solution from the first test sample solution; irradiating the second test sample solution with light; collecting scattered light signals generated by particles in the second test sample solution; and acquiring a second measurement result of red blood cells and platelets in the second test sample solution based on the scattered light signals. Thus, RBC and PLT can be accurately classified especially under a condition of using an ordinary diluent.
AIR MEASUREMENT DEVICE
An inexpensive, yet accurate particle matter (e.g., PM) detector is described that combines the features of two different optical particle sensors with a modeling tool to provide a comprehensive, effective air quality measurement instrument (e.g., sensing instrument). The modeling tool enables the use of a combination low cost optical particle sensors, such as a nephelometer and an optical particle counter to determine the amounts of unhealthy particles that are present in air. The sensing instrument determines the total mass loading at specific size breakpoints, such as PM.sub.1, PM.sub.2.5, and PM.sub.10. In some embodiments, the sensing instrument may include gas sensors so that the particular gaseous pollutants can be identified and measured. In some embodiments, the sensing instrument may further include one or more of a humidity sensor, a temperature sensor, and a pressure sensor.
PREPARATION OF NUCLEATED RBC (NRBC) ANALOGS FOR USE AS REFERENCE HEMATOLOGY CONTROLS IN AUTOMATED HEMATOLOGY ANALYZERS
The subject invention pertains to compositions of novel analogs of red blood cells that are distinguishable from white blood cells in a hematological instrument and processes for manufacturing such analogs. The processes for creating the compositions comprise washing, shrinking, and fixing cells at temperatures at or below room temperature.
Ice nucleii counter technology
A method and system of measuring the size distribution of particles within dilute colloids, for example, through variation of the minimum ice-nucleation sizes of particles within the colloid. The system for measuring particles in fluids includes, a sample fluid inlet and an ice nuclei counter communicatively connected to the sample fluid inlet, the ice nuclei counter cooling the sample fluid and measuring particles which form crystals in the cooled fluid. The method for measuring particles in fluid includes the steps of providing a sample fluid, cooling the sample fluid, and measuring particles which form crystals in the cooled fluid.
METHOD OF CONTROLLING A BLOOD ANALYZER FOR MEASURING PLATELETS
A method of controlling a blood analyzer for measuring platelets is provided. The method comprises: determining a relationship between at least one first measurement value obtained by detecting platelets in at least one previous test by an electrical type detector of the blood analyzer and at least one second measurement value obtained by detecting the platelets in the at least one previous test by an optical type detector of the blood analyzer, and controlling the blood analyzer to prepare the first and/or second measurement sample for a current test according to the determined relationship.