The invention relates to a stationary phase medium for adsorption chromatography, which is in form of porous particles suitable for being packed into a chromatographic column. The porous particles are made of cross-linked polymeric material and formed with interconnected macropores to constitute a porous network, through which a mobile phase fluid may flow in a convective manner. The porous particles are substantially free of diffusive pores and, thus, the mass transfer through the porous network is governed by convection alone. The porous particles are fabricated to have irregular granular configurations with rough outer surfaces, so that the convective flow between the porous particles will not be impeded during chromatography process.

Disclosed are methods of making a porous particle material for use as stationary media and related chromatographic separation devices utilizing the disclosed stationary media. The porous particle material has a pore volume that yields improved stability and column lifetime, and additionally has a modified surface, resulting in a surface modified porous particle material that improves the separation of AAVs from their aggregates in the samples to be tested.

A nanocomposite comprising MgAl.sub.2O.sub.4 includes 1 weight percent (wt. %) to 10 wt. % nickel oxide and 1 wt. % to 10 wt. % cobalt oxide. The nickel oxide and the cobalt oxide are doped in the MgAl.sub.2O.sub.4. The nanocomposite is in the form of particles with an average particle size ranging from 1 nanometer (nm) to 8 nm and a surface area of 100 square meters per gram (m.sup.2/g) to 150 m.sup.2/g.

Disclosed are methods of making a porous particle material for use as stationary media and related chromatographic separation devices utilizing the disclosed stationary media. The porous particle material has a pore volume that yields improved stability and column lifetime, and additionally has a modified surface, resulting in a surface modified porous particle material that improves the separation of AAVs from their aggregates in the samples to be tested.

Adsorbents for removing contaminants from hydrocarbon streams are described. The adsorbents comprise polyurethane foam comprising a metal compound. The polyurethane foam can be rigid or flexible and has a structure comprising a combination of open cells and closed cells. Methods of removing contaminants from hydrocarbon streams using the adsorbent are also described.