Mixers for adhesives and sealants that include automatic stroke length adjustment for different sizes and configurations of adhesive and sealant cartridges are disclosed. The mixers include a sensor for detecting when a mixing impeller reaches the top of a cartridge and the bottom of a cartridge, which sends a signal to a main pressure cylinder to reverse direction. The stroke length of the mixer is automatically adjusted without the necessity of manual selection based upon a particular cartridge size.

A flow shifter baffle for mixing a fluid flow having at least two components, a static mixer, and method of mixing are described. The flow shifter baffle includes a double divider wall element adjacent to a leading edge and a plurality of occluding walls coupled to the double divider wall element. The double divider wall element includes first and second generally parallel walls which extend across the entire transverse flow cross-section. The double divider wall element is configured to divide the fluid flow into a central flow portion and first and second peripheral flow portions. This division of the fluid flow using the double divider wall element and the plurality of occluding walls improves the mixing of separate components by producing a greater number of layers with less jumbling of the layers, when a layered composition of multiple components is delivered into the flow shifter baffle.

Varied embodiments of a container/dispenser having a multi-chamber bellows member having a plurality of collapsible bellows chambers allowing more than one substance to be contained within the container and simultaneously dispensed when a sufficient axial force is exerted on a platform to compress the bellows member forcing flowable materials from each chamber. In an alternative embodiment, the present invention discloses a retrofit multi-chambered bellows container, which may be adapted to a standard caulking tube container.

A reagent preparation assembly includes a body and a reaction chamber adjacent the body, the reaction chamber includes a reagent therein, such as a lyophilized reagent. An access port extends into the reaction chamber, and the access port is configured to receive an instrument. A seal extends across a portion of the reaction chamber and the access port. A reconstitution assembly is movably coupled with the body. The reconstitution assembly includes a plunger, a syringe and a piston. The plunger is movably coupled with the body. The syringe is selectively engaged with the plunger. The syringe includes a solution reservoir containing a solution, and movement of the syringe pierces the seal. The piston is selectively engaged with the plunger, and the piston is movably coupled within the syringe. Movement of the piston pushes the solution into the reaction chamber.

A bone material for hydration with a liquid is provided, the bone material comprising a coherent mass of milled and demineralized bone fibers, the coherent mass having no binder disposed in or on the coherent mass. In some embodiments, a bone material for hydration with a liquid is provided, the bone material comprising a coherent mass of cartridge milled, lyophilized and demineralized bone fibers, the coherent mass having no binder on the coherent mass. In some embodiments, a method of implanting a bone material is provided, the method comprising contacting the bone material with a liquid, the bone material comprising a coherent mass of cartridge milled, lyophilized and demineralized bone fibers, the coherent mass having no binder disposed in or on the coherent mass; molding the bone material into a shape to implant the bone material; and implanting the bone material at the target tissue site.

An entry mixing element is provided for mixing an incoming fluid flow having first and second unmixed components arranged so as to define a transverse flow cross-section perpendicular to a flow direction. The entry mixing element includes a central axis configured to be aligned with the flow direction of the incoming fluid flow, and an entry dividing wall extending parallel to the central axis and positioned to divide the incoming fluid flow into first and second fluid flow portions, each portion containing an amount of the first component and an amount of the second component. The entry dividing wall is configured to divide the incoming fluid flow into the first and second fluid flow portions in any rotational orientation of the entry mixing element about its central axis relative to the transverse flow cross-section of the incoming fluid flow. Related static mixers and methods of mixing are also provided.

A manual mixer serves to facilitate mixing and agitating materials for use during surgery. The manual mixer includes a mixing assembly and an actuation assembly for actuating the mixing assembly. The mixing assembly includes at least a paddle portion and a plunger portion. The plunger portion is simultaneously capable of rotational movement with the paddle portion and movement upwardly or downwardly along the paddle portion. Rotation of the paddle portion serves to facilitate mixing and agitating of the materials, and downward movement of the plunger portion serves to facilitate dispensing of the materials from the manual mixer.

A device for producing a bone cement dough from a monomer liquid and a cement powder and dispensing the bone cement dough. The device includes a cartridge holding the cement powder in an internal space. A monomer receptacle screws onto the cartridge, forms a chamber, and has a plunger with a passage that is permeable to gases and the monomer liquid but is impermeable to the cement powder and that connects the internal space to the chamber. The plunger tightly closes the internal space with the exception of the passage. A gas supply opening is arranged in the wall of the monomer receptacle. A monomer liquid container holds the monomer liquid and is located in the chamber. An opening facility opens the container, and closes the gas supply opening before opening the container. Also provided is a method for producing and dispensing the bone cement dough.

A combination plunger, a mixing device and a mixing syringe including the same are provided. The mixing syringe includes concentric outer and inner barrels that form an outer chamber, the inner barrel having an inner chamber. The combination plunger includes a mixing plunger and a delivery plunger and a biasing means. The mixing plunger is slidably located in the outer chamber and translated by coordinated depression of the delivery plunger to transfer a first substance from the outer chamber to mix with a second substance in the inner chamber. After the mixing stage is complete, the delivery plunger is disengaged from the mixing plunger and permitted, such as by rotation, to be further depressed in the axial direction to deliver fluid contents of the mixing syringe to a recipient. The mixing syringe needle is then retracted as result of engagement by the delivery plunger and activation of the biasing means.

A mixer assembly with a static mixing element arranged within a mixing channel. The mixer assembly has an inlet end, for receiving components of a substance and a dispensing end for dispensing a mixture from the components. The inlet end comprises for each component an inlet and an associated non-return valve. Each of the inlets is connectable for fluid communication with the mixing channel via the associated non-return valve.