There is provided a microfluidic chip for sensing an analyte in a sample by colorimetry. The microfluidic chip comprises: an inlet adapted to receive the sample; an incubation chamber having an incubation chamber inlet fluidly connected to the inlet downstream thereof, to incubate the analyte in the sample; a filter barrier fluidly connected to the incubation chamber, downstream of the incubation chamber inlet; a sensing chamber fluidly connected to the incubation chamber, downstream of the filter barrier, the sensing chamber having a plasmonic nanosurface, the plasmonic nanosurface including nanostructures protruding from the plasmonic nanosurface, the nanostructures having a size that is smaller than that of the diffraction limit of light, the nanostructures having a metallic layer that is plasmon-supported on top of a back reflector layer; and an outlet fluidly connected to the sensing chamber downstream thereof.

There is provided a microfluidic device for reversing a flow through a microfluidic channel. The microfluidic device comprises a first microfluidic channel extending between a first inlet and a first outlet, a second microfluidic channel which fluidically connects a first point of the first microfluidic channel to a second outlet via a first valve, a third microfluidic channel which fluidically connects a second point of the first microfluidic channel to a second inlet via a second valve, the second point being located between the first point and the first outlet, and at least one circuit for opening the first valve and the second valve. The first and the second valves are arranged to be initially closed, Upon opening of the first and the second valve during use, the flow direction through the first microfluidic channel between the first point and the second point is reversed.

A fluid device includes a substrate and a gas-liquid separating filter, the substrate has a flow path through which a solution flows, a reservoir, in which the solution is accommodated, connected to the flow path, an injection hole configured to connect the reservoir to the outside, and an air introduction hole branched off from the injection hole and connected to the outside, and the gas-liquid separating filter is disposed in a path of the air introduction hole, allows passage of a gas flowing through the air introduction hole, and prevents passage of a liquid flowing through the air introduction hole.

A solid reagent containment unit is formed by a support; a frame body fixed to the support and delimiting internally, together with the support, an analysis volume; a reagent-adhesion structure within the analysis volume; and at least one reagent cavity, which extends within the reagent-adhesion structure. The reagent-adhesion structure is of an adhesion material embossable at temperatures lower by 6-8° C. than its own melting point and has a melting point such as not to interfere with the analysis. The reagent cavity forms a retention wall, laterally surrounding the reagent cavity, and houses dried reagents. The adhesion material is chosen among wax, such as paraffin, a polymer, such as polycaprolactone, a solid fat, such as cocoa butter, and a gel, such as hydrogel or organogel.

A fluidic device for processing a fluid or species therein is described. The device comprises a 3D channel including an inlet for receiving a sample fluid and an outlet for outputting the sample fluid. The channel is adapted for guiding flow of the sample fluid in an axial direction from the inlet to the outlet. The channel includes at least two side walls. The device also has a controllable flow inducer having electrodes for inducing, when the sample fluid is flowing through the channel, a motion of the sample fluid in the channel in a plane substantially orthogonal to the axial direction. Along at least one of the side walls at least part of the electrodes are formed by alternatingly at least an electrically conducting portion, an electrically insulating portion and a further electrically conducting portion.

A system and method for sorting sperm is provided. The system includes a housing and a microfluidic system supported by the housing. The system also includes an inlet providing access to the microfluidic system to deliver sperm to the microfluidic system and an outlet providing access to the microfluidic system to harvest sorted sperm from the microfluidic system. The microfluidic system provides a flow path for sperm from the inlet to the outlet and includes at least one channel extending from the inlet to the outlet to allow sperm delivered to the microfluidic system through the inlet to progress along the flow path toward the outlet. The microfluidic system also includes a filter including a first plurality of micropores arranged in the flow path between the inlet and the outlet to cause sperm traveling along the flow path to move against through the filter and gravity to reach the outlet.

A sampling structure, a sealing structure and a detection assembly are provided. The sampling structure includes a first main body, a second main body and a third main body. The first main body includes a first channel, the first channel includes a first opening that is exposed. The second main body is connected to the first main body and includes a second channel and at least one partition column located in the second channel, the second channel is linked with the first channel, and a first gap is between the partition column and a channel wall of the second channel. The third main body is connected to the second main body and includes a chamber, the chamber is linked with the second channel and is capable of containing a sample.

A method for concentrating microorganisms, includes modifying an object by introducing an amine group into the object (step 1); and contacting a sample including a microorganism and dimethyl 3,3′-dithiobispropionimidate (DTBP) each other on the modified object (step 2), wherein the object is any one of a thin film device, a magnetic bead, a ring resonator, and a nanoparticle.

Microfluidic method and device that can be used for sensing and measurement of properties of liquids, gases, solutions, and particles is proposed, wherein the measurable liquid or gas (with or without particles) flow in at least one channel through a measurement chamber (cell) formed between at least two isolated electrodes is used for electrical impedance measurement. The proposed solution is characterized in that the cross-section of at least one pair of similar spatial electrodes decreases smoothly towards the tiny measurement chamber (cell) in order to increase the sensitivity and accuracy of the measurement. Typically, a device with multiple similar channels is advantageous to use for comparative measurement and differential measurement schemes.

Single-use diagnostic consumables for use in performing multiple analyses on a fluid sample are provided. The diagnostic consumables include a first sensing region configured for analysis of at least one analyte in a fluid sample that has been received by the diagnostic consumable. The diagnostic consumable further includes a fluid transport material configured to flow a portion of the fluid sample into a second sensing region fluidically connected to the fluid transport material and configured for performing a second analysis of the fluid sample. Methods for performing multiple analyses of a fluid sample on a single-use diagnostic consumable are also provided.