B01J20/3208

Affinity support and method for trapping substance using the same
10968263 · 2021-04-06 · ·

Problems to be Solved The present invention provides an affinity support capable of trapping a substance by cooperative binding that is less likely to cause dissociation even when the substance is a molecule other than an antibody, and a trapping method using the same. Means to Solve the Problems A method of trapping a substance comprising the step of contacting an objective to be trapped with an affinity support comprising a support, a spacer bound to the support and an affinity substance bound to the spacer, so as to bind the objective to be trapped to the affinity substance, wherein each one of the objective to be trapped has a plural of affinity sites and the affinity substance binds to at least two of the affinity sites simultaneously.

CORE-SHELL COMPOSITE PARTICLES AND METHODS OF MAKING SAME
20210101848 · 2021-04-08 ·

A composite particle is described herein. The composite particle can contain a seed particle of an agricultural treatment material and a shell disposed on the seed particle, wherein the shell comprises a clay.

Compositions and methods for combining protein precipitation and solid phase extraction

A composition, method and device for the preparation of biological samples for subsequent LC-MS analysis using a combined and concurrent protein precipitation and solid phase extraction (SPE) process is described. Through an integrated combination of protein precipitation, filtration, and SPE using a novel zirconia-coated chromatographic media, interfering compounds, such as proteins and phosphate-containing compounds, are eliminated from the biological samples, affording a higher degree of analyte response during LC-MS analysis.

METHODS WITH A CONSTRUCTION THAT ABSORBS AN ORGANIC CHEMICAL

Construction for absorbing a fluid, for example, a liquid or gaseous, organic chemical, has an extended web, fabric, yarn or foam member and associated with the extended web, fabric, yarn or foam member is a water-insoluble polymer. The water-insoluble polymer can absorb the fluid organic chemical, and the construction provides for contact of the water-insoluble polymer with the fluid organic chemical when deployed in an environment where the fluid organic chemical may be present for absorption. The construction may be employed in aquatic, aqueous, or dry environments, as a blotter, a wipe or sponge, a filter, in a cartridge, and so forth.

Gas filters for basic contaminants

An example article includes a substrate and a coating applied to the substrate. The coating includes a stabilizer and an organic phosphonic acid reactant. In an example article, the coating includes a water-soluble polymer and an organic phosphate or phosphonate reactant. An example coating configured to be applied to a basic gas filter substrate includes a water-soluble polymer and an organic phosphate or phosphonate reactant. An example technique includes applying a coating to a substrate and heating at least the coating to a temperature between about 100 C. and about 275 C. for about 1 minute to about 10 minutes. An example system includes a basic gas filter including a coating, and a sensor configured to sense an optical change in the coating.

CHROMATOGRAPHY RESIN HAVING AN ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE LIGAND
20210086165 · 2021-03-25 ·

Chromatography resins having mixed mode ligands and methods of using such resins are provided.

WATER VAPOR HARVESTING MATERIALS AND DEVICES
20210069639 · 2021-03-11 ·

An atmospheric water harvesting material includes a deliquescent salt, a photothermal agent, and a polymeric hydrogel matrix containing the deliquescent salt and photothermal agent.

Sample depletion and enrichment to improve the quality of diagnostic test results
10948484 · 2021-03-16 · ·

Magnetic and non-magnetic microparticle binding surfaces for the simple, cost-effective and automatable depletion of sample interferences within the assay blocking threshold and enrichment of biomarkers are provided, as are methods and compositions for their preparation and use. The binding surfaces may comprise non-magnetic, magnetic, paramagnetic, and superparamagnetic microparticles, or combinations thereof. The methods include methods for making microparticulate binding surfaces that consist of binders, binding partners, capture moieties, or combinations thereof for multi-functional sample depletion and enrichment. Specific examples employing antibodies or fragments thereof are provided, as well as strepavidin-coated microparticles and microparticles coupled with capture moieties such as immunoglobulins. Other examples couple ligands, enzymes, and proteins, or other biologicals, polymers and chemicals commonly used in the diagnostic test formulation or design. Further provided are binding surfaces consisting of a plurality of microparticles and methods for making them. Use of the methods and compositions in connection with the depletion and enrichment of a wide variety of interferences and biomarkers is provided, particularly for use in primary blood collection tubes, secondary transfer tubes and challenging sample types such as urine, saliva and stool.

Low temperature synthesis of aluminum hydr(oxide) inside porous media

Preparing a porous hybrid media includes contacting porous media (e.g., strong base ion-exchange media) with an aqueous solution including aluminum ions to yield a aluminum-ion-containing porous media, contacting the aluminum-ion containing porous media with a reducing agent to impregnate elemental aluminum in the porous media, and oxidizing the elemental aluminum to yield a porous hybrid media including aluminum hydr(oxide) impregnated in the porous media. In some cases, a pH of an aqueous mixture including the aluminum-ion-containing porous media may be adjusted to form a floc including aluminum hydroxide, and the aluminum hydroxide-containing porous media may be contacted with a reducing agent to yield a porous hybrid media including aluminum hydr(oxide) impregnated in the porous media. The porous hybrid media may advantageously be prepared at low temperature (e.g., room temperature).

ACTIVE CARBON FILTER FOR A CARBON CANISTER AND A METHOD FOR PRODUCING THE SAME

A method for producing an active carbon filter for a carbon canister includes forming a body having a honeycomb structure with a plurality of bleed passages from a polymer based material, and forming an adsorption layer along a surface of the body, where the adsorption layer is made of a carbon based material.