The subject technology is directed to a CO.sub.2-based chromatography system and method for rapid determination of the levels and/or the presence or absence of steroids or steroid derivatives in a sample.

The present disclosure discloses an efficient and regenerable nano manganese remover, and a method for preparing same and application thereof, belonging to the technical field of wastewater treatment and reuse. The manganese remover of the present disclosure includes Fe.sub.3O.sub.4, RGO, SiO.sub.2 and EDTA. The Fe.sub.3O.sub.4 nanoparticles are supported on the surface of the RGO, the SiO.sub.2 coats the Fe.sub.3O.sub.4, and the EDTA is grafted on the SiO.sub.2. First, Fe.sub.3O.sub.4-RGO is prepared. Then, a TEOS-ethanol solution is dropwise added, and the resulting mixture is allowed to react to obtain Fe.sub.3O.sub.4@SiO.sub.2-RGO composite particles. Finally, an EDTA-water solution is dropwise added to obtain the manganese remover. The manganese remover prepared in the present disclosure is magnetic, and the preparation process is simple and easy for industrial production. The nano manganese remover can quickly remove manganese in manganese-containing wastewater. A small amount of the manganese remover can achieve a large adsorption capacity. Further, the nano manganese remover can be separated from the manganese-containing wastewater quickly, thereby avoiding secondary pollution to the system.

An article that can be used for biomaterial capture comprises (a) a porous substrate; and (b) borne on the porous substrate, a polymer comprising interpolymerized units of at least one monomer consisting of (1) at least one monovalent ethylenically unsaturated group, (2) at least one monovalent ligand functional group selected from acidic groups, basic groups other than guanidino, and salts thereof, and (3) a multivalent spacer group that is directly bonded to the monovalent groups so as to link at least one ethylenically unsaturated group and at least one ligand functional group by a chain of at least six catenated atoms.

Methods of producing and isolating .sup.68Ga, .sup.89Zr, .sup.64Cu, .sup.63Zn, .sup.86Y, .sup.61Cu, .sup.99mTc, .sup.45Ti, .sup.13N, .sup.52Mn, or .sup.44Sc and solution targets for use in the methods are disclosed. The methods of producing .sup.68Ga, .sup.89Zr, .sup.64Cu, .sup.63Zn, .sup.86Y, .sup.61Cu, .sup.99mTc, .sup.45Ti, .sup.13N, .sup.52Mn, or .sup.44Sc include irradiating a closed target system with a proton beam. The closed target system can include a solution target. The methods of producing isolated .sup.68Ga, .sup.89Zr, .sup.64Cu, .sup.63Zn, .sup.86Y, .sup.61CU, .sup.99mTC, .sup.45-Ti, .sup.52Mn, or .sup.44Sc by ion exchange chromatography. An example solution target includes a target body including a target cavity for receiving the target material; a housing defining a passageway for directing a particle beam at the target cavity; a target window for covering an opening of the target cavity; and a coolant gas flow path disposed in the passageway upstream of the target window.

The invention relates to a lock-release method to be applied to biomolecules, such as antibodies, to improve the purification, production, stability and storage of biomolecules. A biomolecule is covalently bound to a polymer support comprising a diketone group so that the biomolecule can be purified, produced and/or stored before being released from the support. The diketone group of the polymer support is a 1,3-ketoester, 1,3-ketothioester or 1,3-ketoamide is a group of Formula (1): R.sup.1 is an optionally substituted hydrocarbyl, perhalogenated hydrocarbyl, or a heterocyclyl group; Y is hydrogen, an optionally substituted hydrocarbyl, or a heterocyclyl group; X is —O, —NR.sup.2 or —S, wherein the free valence of —O, —NR.sup.2 or —S is bonded to the support optionally via a linker; and R.sup.2 is hydrogen, an optionally substituted hydrocarbyl, or a heterocyclyl group. The invention also relates to a polymer support comprising the diketone group. ##STR00001##

The invention relates to the use of a citrate solution for affinity-chromatographic removal of C-reactive protein (CRP) from biological fluids, wherein the CRP is affinity-chromatographically removed using (Ca.sup.2+-dependent) binding of CRP to a column material functionalized with ω-phosphonooxyalkyl ammonium groups and/or with ω-ammoniumalkoxy-hydroxy-phosphoryloxy groups.

A carbon dioxide adsorbent including silica gel and an amine compound carried by the silica gel. The silica gel has a spherical shape, a particle size ranging from 1 mm to 5 mm inclusive, an average pore diameter ranging from 10 nm to 100 nm inclusive, a pore volume ranging from 0.1 cm.sup.3/g to 1.3 cm.sup.3/g inclusive, and a waterproof property N that is defined by an expression (1) and that is not lower than 45%,

N=(W/W.sub.0)×100  (1) where N is the waterproof property in percentage (%) of the silica gel, W.sub.0 is a total number of particles of the silica gel immersed in water, W is a number of particles of the silica gel not subjected to breakage out of W.sub.0.

A variety of inorganic-organic hybrid materials and various methods for preparing and using the same are described. The hybrid materials are graphene or graphitic materials populated with organic molecules and may have a variety of surface defects, pits or three-dimensional architecture, thereby increasing the surface area of the material. The hybrid materials may take the form of three dimensional graphene nanosheets (3D GNS). If the organic molecules are enantiospecific molecules, the hybrid materials can be used for chiral separation of racemic mixtures.

The invention concerns methods of removing undesirable molecules from the blood or physiologic fluid; said method comprising contacting said blood or physiologic fluid with a sorbent, said sorbent comprising a plurality of solid forms and comprising a cross-linked polymeric material having a plurality of ligands attached to the surface of said cross-linked polymeric material, comprising (i) zwitterionic moieties, (ii) oligo(ethylene glycol) moieties or (iii) mixtures thereof; said contacting comprising said sorbent sorbing a plurality of said undesirable molecules when said sorbent is administered within a patient's body.

In one embodiment, a method of removing a substance from a solution by adsorption includes: interfacing a delivery component containing a quantity of amine functionalized chitin (AFC) compound as an adsorbent AFC compound with the solution containing the substance as an adsorbate substance; mixing the adsorbent AFC compound and the adsorbate substance in the solution for a period of time; and removing a mixture of the adsorbent AFC compound and at least a portion of the adsorbate substance from the solution.