Patent classifications
C08J2379/02
Preparation Method for Charge Reversaland Reversibly Crosslinked Redox-Sensitive Nanomicelles
Disclosed is a preparation method for charge reversal and reversibly crosslinked redox-sensitive nanomicelles, falling within the technical field of biomedical materials. The method comprises: synthesizing thiocinamide from lipoic acid and ethylenediamine under an N,N-carbonyl diimidazole catalyst; and polymerizing thiocinamide, polyethylene glycol diglycidyl ether and lysine through a nucleophilic addition mechanism to prepare a poly(lysine-co-polyethylene glycol diglycidyl ether-co-thiocinamide) terpolymer. The micelle is endowed with excellent anti-protein nonspecific adsorption and enhanced cell uptake property through a self-assembly and protonation/deprotonation action; and a disulfide bond in lipoyl may form a linear polydisulfide structure under the action of 1,4-dithiothreitol, so that a micelle core is crosslinked, and a crosslinked structure is destroyed in the cell under a redox condition, and controlled release of a drug can be achieved. The Nanomicelle of the present invention is expected to be a carrier of drugs for treating cancers.
BINDERS
The present invention relates to binder compositions with improved amine components, and a method of manufacturing a collection of matter bound by said binder compositions.
Polydopamine film and preparation method and application thereof
Disclosed are a poly dopamine film and a preparation method and application thereof. The polydopamine film is loaded with silver sulfadiazine, and the preparation method achieves in-situ synthesis of si sulfadiazine on a conventional polydopamine film by microwave irradiation. In the method, the sulfadiazine is not dissolved in conventional aqueous ammonia, which has the following advantages: firstly, preventing the polydopamine film from being corroded by the aqueous ammonia; secondly, protecting mucosa such as eyes and nasal cavities of workers from stimulation and corrosion of the aqueous ammonia; and thirdly, avoiding the environmental problem caused by pungent odor and fumes emitted from high-concentration aqueous ammonia. In the method, without using the catalyst trifluoromethanesulfonic acid or trifluoromethanesulfonic salt, not only is the loading of silver sulfadiazine increased, but also the safely performance can be further improved.
Curable compositions containing benzoxazine epoxy blend and use thereof
A curable resin composition capable of providing good OHC performance at elevated temperatures when used in polymer matrix composites. This resin composition includes, as major components, one or more multifunctional benzoxazine compounds and cycloaliphatic epoxy resin.
BENZOXAZINE BASED COPOLYMER AEROGELS
The present invention relates to a benzoxazine based copolymer aerogel obtained by reacting a benzoxazine monomer or oligomer and a comonomer selected from the group consisting of an isocyanate compound, a cyclic ether compound and an acid anhydride compound in a presence of a catalyst and a solvent, wherein said catalyst is an optional ingredient when said comonomer is an acid anhydride compound or an isocyanate compound. Benzoxazine based copolymer aerogel according to the present invention provides high thermal insulation material, while good mechanical properties and performance is maintained.
SYSTEMS AND METHODS FOR COMPOSITE RADIUS FILLERS
A composite radius filler material is provided. The composite radius filler includes a resin, a first group of fibers dispersed within the resin, and a second group of fibers dispersed within the resin. The first group of fibers has a first length configured to facilitate orientation in a longitudinal direction. The second group of fibers has a second length that is shorter than the first length, with the second group of fibers configured to facilitate random orientation in a transverse direction.
SALTS OF DIAMINOACETALS AND DIAMINOKETALS AND THEIR SYNTHESIS, AND THEIR TRANSFORMATIONS TO DIAMINOACETALS AND DIAMINOKETALS
This application relates, in part, to novel salts represented by the following structure of Formula (1):
##STR00001##
wherein R.sup.1a is selected from the group consisting of hydrogen and optionally substituted alkyl (e.g., unsubstituted C.sub.1-6 alkyl, e.g., CH.sub.3); R.sup.1b is optionally substituted alkyl (e.g., unsubstituted C.sub.1-6 alkyl, e.g., CH.sub.3); each occurrence of R.sup.2 and R.sup.3 is independently selected from the group consisting of hydrogen, optionally substituted alkyl, optionally substituted cycloalkyl, and optionally substituted aryl; R.sup.2 and R.sup.3 can combine with each other to form optionally substituted cycloalkyl; each m and n is independently an integer ranging from 1 to 20 (e.g., m and n is independently an integer ranging from 1 to 5); and each of Q.sup.1.sup.
SILICON-CONTAINING COMPOSITIONS AND THEIR METHODS OF USE
Provided herein are silicon-containing recyclable polyamino compounds; epoxy resin compositions containing these silicon-containing reworkable or recyclable polyamino compounds; and methods of their use.
Process For Producing Dye-Containing Heat-Curable Resin Particles
The present invention provides a method of producing dye-containing thermosetting resin particles, the method including: dispersing seed particles formed from a thermosetting resin in a dispersion medium; and polymerizing a monomer for thermosetting resin synthesis in the thus obtained dispersion in the presence of a dye and an acid catalyst. By the method of producing dye-containing thermosetting resin particles according to the present invention, dye-containing thermosetting resin particles whose particle size variation coefficient is small at, for example, 8% or less, can be produced without performing a post-treatment such as centrifugation. Therefore, when immunological observation is performed by a fluorescent labeling method using fluorescent dye-containing resin particles produced by the method of producing dye-containing thermosetting resin particles according to the present invention, a high bright spot detection accuracy can be attained.
ANTIFOULING FILM
The antifouling film includes a polymer layer that includes on a surface thereof an uneven structure provided with multiple projections at a pitch not longer than a wavelength of visible light. The polymer layer has a proportion of the number of fluorine atoms relative to the sum of the numbers of carbon atoms, nitrogen atoms, oxygen atoms, and fluorine atoms of 33 atom % or more on the surface of the uneven structure. The polymer layer has at least one local maximum of the proportion of the number of nitrogen atoms relative to the sum of the numbers of carbon atoms, nitrogen atoms, oxygen atoms, and fluorine atoms in a region 5 to 90 nm deep from the surface of the uneven structure. The local maximum is 0.3 atom % or more greater than the average value in a region 90 to 120 nm deep from the surface of the uneven structure.