Provided herein are compositions and their methods of use to adhere (e.g., in wet and dry environments) a variety of materials together.

Provided herein are compositions and their methods of use to adhere (e.g., in wet and dry environments) a variety of materials together.

Disclosed are keratin fibre cellular components, specifically keratin fibre cuticle and cortical cells, and their use as absorption and filtration media, and in thermal insulation materials. The keratin fibre cellular components may be oxidised. The keratin fibre cellular components have improved absorbency and filtration capacity compared to the source keratin fibres. The keratin fibre cellular components may be used in, for example, various products for passive absorption and active filtration of gas or liquid media.

Disclosed are keratin fibre cellular components, specifically keratin fibre cuticle and cortical cells, and their use as absorption and filtration media, and in thermal insulation materials. The keratin fibre cellular components may be oxidised. The keratin fibre cellular components have improved absorbency and filtration capacity compared to the source keratin fibres. The keratin fibre cellular components may be used in, for example, various products for passive absorption and active filtration of gas or liquid media.

Provided herein are compositions and their methods of use to adhere (e.g., in wet and dry environments) a variety of materials together.

Provided herein are compositions and their methods of use to adhere (e.g., in wet and dry environments) a variety of materials together.

One aspect of the invention provides a method of treating a chronic wound including administering to the wound at least one agent from a delivery system wherein the agent induces sequential conversion of a first population of wound macrophages in the wound to M2A macrophages and a second population of wound macrophages to M2C macrophages. The sequential conversion of the wound macrophages promotes tissue remodeling.

One aspect of the invention provides a method of treating a chronic wound including administering to the wound at least one agent from a delivery system wherein the agent induces sequential conversion of a first population of wound macrophages in the wound to M2A macrophages and a second population of wound macrophages to M2C macrophages. The sequential conversion of the wound macrophages promotes tissue remodeling.

The formation of scars at a wound site is reduced by contacting the wound site with an effective dose of an inhibitor of focal adhesion kinase (FAK) formulated in a pullulan hydrogel The release profile of the FAK inhibitor can be adjusted according to the nature of the wound, e.g., excisional wounds, burn wounds, etc.

The formation of scars at a wound site is reduced by contacting the wound site with an effective dose of an inhibitor of focal adhesion kinase (FAK) formulated in a pullulan hydrogel The release profile of the FAK inhibitor can be adjusted according to the nature of the wound, e.g., excisional wounds, burn wounds, etc.