The present invention provides a capsule for diagnosis of Helicobacter pylori including a body section into which a gastrointestinal fluid including the Helicobacter pylori is selectively introduced; a decomposition section that is accommodated in the body section and contains urea; a sensor unit for measuring information on a result of decomposing the urea by Helicobacter pylori in the decomposition section; and a control unit for transmitting the information measured by the sensor unit to the outside.

Disclosed are diagnostic test strips to screen for azotemia or kidney disease in felines and canines. The diagnostic test strips comprise an elongate carrier material to which is adhered a test pad assembly comprising a reagents substrate material loaded with urease, a pH indicator, and a buffer for adjusting a pH value of a feline or canine saliva sample to within a transition interval of the pH indicator, a laminate layer, and an adhesive layer. The test strips may additionally comprise a control pad assembly adhered to the elongate carrier material adjacent to the test pad assembly.

Disclosed are diagnostic test strips to screen for azotemia or kidney disease in felines and canines. The diagnostic test strips comprise an elongate carrier material to which is adhered a test pad assembly comprising a reagents substrate material loaded with urease, a pH indicator, and a buffer for adjusting a pH value of a feline or canine saliva sample to within a transition interval of the pH indicator, a laminate layer, and an adhesive layer. The test strips may additionally comprise a control pad assembly adhered to the elongate carrier material adjacent to the test pad assembly.

Disclosed is a urea biosensor that is stable at ambient temperature, and methods of making thereof.

Disclosed are multi-enzyme biosensors that are stable at ambient temperature, and methods of making thereof.

The disclosure relates to electrochemical sensors for measuring creatinine and creatine in a patient's blood. More particularly, the disclosure relates to compositions and methods for improving measurement accuracy of electrochemical sensors used for measuring creatinine and creatine.

Disclosed are multi-enzyme biosensors that are stable at ambient temperature, and methods of making thereof.

The present application discloses improved multiple-use sensor arrays for determining the content of various species in samples of biological origin, in particular in the area of point-of-care (POC) testing for blood gases. The multiple-use sensor array is arranged in a measuring chamber, and the sensor array comprises two or more different ion-selective electrodes including a first ion-selective electrode (e.g. an ammonium-selective electrode being part of a urea sensor), wherein the first ion-selective electrode includes a membrane comprising a polymer and (a) a first ionophore (e.g. an ammonium-selective ionophore) and (b) at least one further ionophore (e.g. selected from a calcium-selective ionophore, a potassium-selective ionophore, and a sodium-selective ionophore), and wherein the first ionophore is not present in any ion-selective electrode in the sensor array other than in the first ion-selective electrode.

The present application discloses improved multiple-use sensor arrays for determining the content of various species in samples of biological origin, in particular in the area of point-of-care (POC) testing for blood gases. The multiple-use sensor array is arranged in a measuring chamber, and the sensor array comprises two or more different ion-selective electrodes including a first ion-selective electrode (e.g. an ammonium-selective electrode being part of a urea sensor), wherein the first ion-selective electrode includes a membrane comprising a polymer and (a) a first ionophore (e.g. an ammonium-selective ionophore) and (b) at least one further ionophore (e.g. selected from a calcium-selective ionophore, a potassium-selective ionophore, and a sodium-selective ionophore), and wherein the first ionophore is not present in any ion-selective electrode in the sensor array other than in the first ion-selective electrode.

A method of detecting a bacterium of the genus Helicobacter, which includes i) inserting an absorbent swab into the stomach of a subject; and ii) absorbing gastric mucus into the absorbent swab of Step i) and separating the absorbent swab from the subject is disclosed. Also disclosed is a kit for detecting a bacterium of the genus Helicobacter, which includes an absorbent swab for absorbing gastric mucus. The method and kit, employing an absorbent swab, improves sensitivity or positive predictive value of a urease test method for detecting a bacterium of the genus Helicobacter, such as Helicobacter pylori, may significantly increase and avoids a side effect such as bleeding which may occur during tissue collection of conventional method.