A01N1/0242

Modular blood product storage system for temperature-regulated storage of blood products
11528904 · 2022-12-20 · ·

Modular blood product storage system for temperature-regulated storage of blood products with a temperature regulation unit for temperature regulation of the blood product storage system, a base unit and at least one agitator unit with an upper connection side, a lower connection side, a movable compartment to receive the blood products and a drive for movement of the compartment, wherein the compartment is arranged between the upper connection side and the lower connection side, wherein the upper connection side of the agitator unit is selectively connectable to the temperature regulation unit or a further agitator unit, and wherein the lower connection side of the agitator unit is selectively connectable to the base unit or a further agitator unit.

Method and apparatus for keeping artificially created tissues alive
11528902 · 2022-12-20 · ·

A device to aid in the production and regeneration of tissues and organs, standing alone, or on or inside of the human body, with a method of fabrication of tissues and organs and use of the device.

Ischaemia-free organ perfusion device and perfusion method

Disclosed is an ischaemia-free organ perfusion device and perfusion method. The perfusion device perfuses an isolated organ at normal temperature during whole transplantation, and comprises a first container, a second container, a first flow path, a second flow path, a third flow path and a fourth flow path. The perfusion device and the perfusion method are capable of maintaining the blood flow of the isolated organ during whole transplantation without interruption by machine perfusion, recovering the blood of the organ, effectively avoiding the interruption of blood supply for the organ during the whole transplantation, and improving the prognosis of organ transplantation.

Cryopreservation jig for cryopreserving cells or tissues

The present invention aims to provide a device for cryopreservation which enables easy and reliable cryopreservation of a cell or tissue. The device for cryopreservation of a cell or tissue of the present invention includes a deposition part on which a cell or tissue is to be deposited together with a preservation solution, wherein a surface of the deposition part includes a protrusion for holding a cell or tissue and a recess for storing a preservation solution.

ACTIVELY COOLED ORGAN TRANSPLANT SYSTEM
20220369625 · 2022-11-24 ·

An organ transplant system provides a pumping and refrigeration unit and a sterile disposable set to maintain a desired temperature of an organ during transplantation and to position the organ adjacent a surgical site during an organ transplantation procedure. Handling and exposure of the organ is minimized while maintaining position and condition of the organ.

Tissue preservation system

The present invention provides a method and apparatus for tissue, such as an allograft, storage and preservation for extended periods of time at room temperature in a sterile tissue culture chamber. The invention further provides a process for maintaining the sterility of tissue using the apparatus as described.

SYSTEM AND METHOD FOR MAINTAINING ORGAN VIABILITY

A system comprises a fluid supply, a pressure regulator, a pressure valve, and a vent assembly. The fluid supply stores a volume of a fluid and is fluidly coupled to an outlet tube. The outlet tube is configured to be fluidly coupled to at least a portion of an organ environment. The organ environment configured to hold an organ. The pressure regulator is fluidly coupled to the outlet tube and is configured to maintain a fluid pressure of the fluid being supplied to the organ environment from the outlet tube. The fluid being supplied is at a pressure range above ambient to maintain the organ in an inflated position. The pressure valve is fluidly coupled to the outlet tube and inhibits increase of the fluid pressure above a threshold. The vent assembly removes excess fluid from the organ environment and includes a vent tube disposed within the organ environment and a vent valve disposed outside of the organ environment.

FIXTURE OF CRYOPRESERVATION JIG AND FREEZING AND THAWING METHOD USING SAID FIXTURE

Provided is a cryopreservation jig fixture including: a base having an upper surface, side surfaces, and a bottom surface; and either a slit on the upper surface of the base or an insertion portion for inserting a cryopreservation jig on the upper surface of the base and a slit having one end opened at a lateral portion of the insertion portion. Also provided is a method of freezing and thawing a cell or tissue, which uses the fixture.

Apparatus for the combined incubation and vitrification of a biological material

An apparatus, that relates to the field of in vitro fertilization, is provided for the combined incubation and vitrification of a biological material. The apparatus can be configured to allow for automatic incubation and vitrification of a viable biological material. Thereby predetermined protocols for handling the biological material can be performed precisely and accurately thus avoiding errors and deviations from the intended protocol, as caused by manual human intervention.

Device for preserving blood products and cellular cultures in a gas medium under pressure
11497207 · 2022-11-15 · ·

A device that can be used to store blood product and/or cellular culture that may or may not be under pressure. The device includes a chamber that can be hermetically sealed and a flexible secondary bag which can be placed in the chamber. The chamber is designed to receive at least one secondary bag that contains a conventional storage bag containing blood product and/or cellular culture. The storage conditions are created in the chamber and may or may not include 1) creating a pressure higher than atmospheric pressure, 2) creating a refrigerated temperature, and/or 3) providing agitation to the secondary bag. The secondary bag is filled with a gas system that is used to facilitate in the storage of the blood product and/or cellular culture. The secondary bag can be made of a material and/or include a coating or film that is impermeable to the gas system and to the gas inside the chamber. The higher-than-atmospheric pressure inside the chamber can be created by pumping an inexpensive gas, for example, air, into the chamber. The gas used to pressurize the chamber can be different from the gas system in the secondary bag.