Among the various aspects of the present disclosure is the provision of compositions and methods for platelet storage supplementation with an amino acid, such as taurine.

A biological sheet storage device includes a fixation arrangement and a storage box. The fixation arrangement includes a first carrier, a second carrier and a fixing piece. The first carrier is configured to carry a biological sheet and positioned on the second carrier. The fixing piece is configured to fix the first carrier on the second carrier. The storage box is configured to encapsulate the fixation arrangement carrying the biological sheet. A limiting mechanism for limiting the fixation arrangement is included in the storage box.

The invention is that of systems of methods for preserving vital assets such as human organs in transit. An exemplary system may include a central software application and processor for storing vital asset identifying information in a database and displaying real-time transit information in relation to the asset to authenticated users. Application programming interfaces are provided to allow authenticated users to monitor location and environmental data transmitted from the proximity of the asset to the central software application for processing and display on graphical user interfaces. An exemplary system enables methods of reallocating freight from a first to a second transportation asset to avoid delays and prolonged exposures to adverse environmental conditions. In certain embodiments, unmanned aerial systems may be deployed to intervene in the transit channel and overcome such delays or exposures. In preferred embodiments, historical data is collected and analyzed to help predict human organ transplant outcomes.

An organ container has a pouch-shaped body having contraction and expansion properties and an opening. In a no-load condition, a maximum width of the opening is less than a maximum width of the body. On the other hand, the opening is expandable to a state in which the maximum width of the opening becomes greater than the maximum width of the body. Thus, the organ container covers the surface of an organ along the surface of the organ. Accordingly, when an organ is placed in the body cavity of a recipient, the organ container does not expand around the organ. For this reason, the organ container is less likely to hinder work during operation. Moreover, the organ container covers most part of the organ and thereby suppresses a temperature rise in the organ.

Ophthalmic tissue delivery devices that include an injector and injector carriers and methods for endothelial keratoplasty surgical procedures are provided. Injectors include a conduit sized to accommodate ophthalmic tissue. One end of the injector is configured for insertion into a patient's eye to inject ophthalmic tissue. Injector carriers include a container, a cap configured to seal an opening of the container. The injector can be coupled to a pressure actuated valve and a syringe where activating the syringe opens the value and allows fluid to flow from the syringe, through the valve, and through the injector to dispense ophthalmic tissue from the injector into a patient's eye without the need to physically contact the ophthalmic tissue.

Provided is a gas fill fixture for use in lyophilization, a related system and method. The gas fill fixture includes a chassis, fill indicator and a lid, such that the chassis and lid together form a cavity for receiving a flexible lyophilization container. The system includes a lyophilization container, a lyophilizer and a gas fill fixture incorporating a chassis, a fill indicator and a lid. The method includes process steps for using the system to lyophilize a fluid.

Compositions, devices, and systems comprising a corneal tissue carrier, wherein the corneal tissue carrier comprises a corneal tissue sample and a fluid; wherein the fluid comprises resazurin. Additionally, methods including measuring cell viability.

Electrochemical apparatus and method provide a source of electrons to a living organ in the process of transplantation. The organ, depleted of antioxidants, is placed into a vessel supplied with appropriate physiological solution and apparatus that create antioxidative environment.

According to an embodiment of the disclosure, a vial cap is configured for sealing attachment to a tube set and to a vial having a hollow interior configured for receiving and storing a liquid sample. The vial cap may comprise an axially extending cylindrical wall and a radially extending cap top disposed within the cylindrical wall, wherein the cap top has an upper surface and a lower surface. The vial cap may include at least two exterior tubes extending upwardly from the upper surface of the cap top, wherein each exterior tube defines a passageway configured to communicate with the tube set. The vial cap may further include at least two interior tubular structures extending downwardly from the lower surface of the cap top, wherein the at least two interior tubular structures each define a passageway configured to communicate with one of the exterior tubes and the hollow interior.

An organ transplant system provides a pumping and refrigeration unit and a sterile disposable set to maintain a desired temperature of an organ during transplantation and to position the organ adjacent a surgical site during an organ transplantation procedure. Handling and exposure of the organ is minimized while maintaining position and condition of the organ.