An occluder (100) and system. The occluder (100) includes a body (110) including a shaping wire (111) and a spring coil (112), the shaping wire (111) formed by a resilient metal wire and configured to have a predetermined shape, the spring coil (112) sleeved on the shaping wire (111) in order to shape the body (110) with the predetermined shape. Through maintaining the shape of the body (110) by means of the shaping wire (111), the body (110) is able to effectively block the breach (30) in aortic dissection treatments.

Methods for treatment of a cerebral aneurysm within a cerebral vasculature of a patient are described. A microcatheter and a device for treatment of the aneurysm are provided. The device is a self-expanding resilient permeable shell having a plurality of elongate resilient filaments with a woven structure. The plurality of filaments includes small and large filaments. The filaments are bundled and secured to each other at a proximal end. A ratio of the total cross-sectional area of small filaments to the total cross-sectional area of large filaments may be between 0.56 and 1.89. The distal end of the microcatheter is advanced to a region of interest within a cerebral artery. The device is advanced through the lumen and out of the distal end of the microcatheter such that the permeable shell deploys and expands within the cerebral aneurysm. The microcatheter is then withdrawn from the cerebral artery.

Devices and methods for occluding the left atrial appendage (LAA) to prevent blood from clotting within the LAA and subsequently embolizing, particularly in patients with atrial fibrillation. A foam implant encapsulated with a tough thromboresistent membrane is placed via transvascular means into the LAA and anchored with adhesives and/or mechanical anchors. Tissue over- and in-growth are optimized to anchor the implant in place and provide a permanent occlusion.

The present invention relates generally to systems and methods for delivering embolic devices into a body lumen of a patient. These embolic devices are applicable to a variety of neurological and/or peripheral applications. In particular, the embolic devices may be used to occlude a vessel within a patient, and/or to treat aneurysms, arteriovenous malformations, traumatic fistulas, uterine fibroids or cancer.

A method is described herein for the treatment of intracranial aneurysms. The method comprises inserting into an aneurysm an embolism coil coated with a polymeric coating comprising a genipin, such as genipin or a derivative thereof, thereby increasing the stability of clots within the aneurysm. According to one example, the coating is a poly(L-lactide-co-glycolide) (PLGA) is used to release genipin to crosslink fibrin clots thereby creating more stable occlusions. Increased clotting can improve segregation of the weakened portion of the blood vessel from the rest of the vasculature and reduce the risk of recurrence.

The present disclosure provides a variety of prostheses, delivery systems and techniques to facilitate closure of transvascular or transcameral access ports. Various embodiments of prostheses are provided including a plurality of radially expandable discs that can be filled with material to facilitate coagulation and to reduce or stop leakage from punctures in vessel walls.

A system for delivering a device into a body lumen of a patient, the system including a device having a marker band and a tube at a proximal portion, and a pusher member having a ribbon and a ball or hook at a distal portion of the delivery member and a compression coil positioned over the ribbon, the ball or hook releasably engageable with the tube.

The present invention provides for implant device delivery apparatuses and related methods of use. The delivery systems of the present invention incorporate a stretch resistant tube that advantageously makes the implant device, such as an embolic coil, stretch resistant while a delivery system is being used to position the implant device at a desired target site.

A system for occluding a dissection tear includes a stent and at least one occluder and is such configured that the stent and the occluder are separate from each other prior to the delivery of the system to a targeted site and connect to each other after the delivery of the system to the targeted site. The stent and the occluder are separately delivered and released in a diseased blood vessel to significantly reduce the resistance encountered during delivery and release of the stent and the occluder. Moreover, when introducing the occluder into the false lumen, only the profile of the occluder needs to be adjusted, resulting in a lowered surgical difficulty and an improved surgical success rate.

An embolic material which prevents flow of a biological fluid by being placed in a body lumen via a catheter, the embolic material comprising a material that swells by contacting the biological fluid. The embolic material includes a long filler that is formed smaller than an inner diameter of the catheter. The filler prevents the flow of the biological fluid by bending when brought into contact with the biological fluid due to the difference in swelling characteristics between a first side portion and a second side portion that extend parallel to one another in a longitudinal direction.