A handheld cold plasma device in which the device includes power source, control electronic circuit boards connected to high-frequency high-voltage transformers, user control panels, insulating case covering control electronic circuits, high-frequency high-voltage transformer and user control panel to form a monoblock, the plasma generating unit contains the active electrode and the passive electrode outside the housing to allow the user to be connected to the neutral wires of the device. The device according to the present disclosure uses the principle of direct discharge (or dielectric barrier discharge with floating electrodes) with small size, inexpensive and does not use consumable materials.

An electrotechnical core for generating a cold atmospheric pressure or low-pressure plasma for the treatment of human, animal, or technical surfaces. The core has a side facing the surface and a side facing away from the surface and comprises the following layers, starting from the side facing the surface: a first insulation layer, a first electrode structure with a first contact between the first electrode structure and a power supply unit, a second insulation layer to galvanically isolate the first electrode structure and a second electrode structure from one another, wherein the second electrode structure is driven during operation by a voltage signal sufficient to ignite a plasma, a third insulation layer to galvanically isolate the second electrode structure from a third electrode structure, wherein the third electrode structure grounds the third electrode structure during operation.

Disclosed is a method for treating actinic keratosis of tissue of a patient, the method including contacting non-thermal, atmospheric pressure plasma over areas of the tissue having actinic keratosis for a time and at treatment conditions effective to give rise to an at least partial amelioration of the keratosis.

A device and method for treating a hollow anatomical structure using matter in a plasma state. Device includes a tubular delivery device comprising a tubular body, a hub, and a distal end, wherein the tubular body device having a longitudinal fluid delivery channel and an exit port near the distal end. Device also contains a container having pre-plasma matter being operatively coupled to the hub, at least one energy-emitting element operatively coupled near the distal end of the tubular delivery device. The energy-emitting element is operatively connected to energy source.

A probe for ablating tissue comprises an electrosurgical working end configured to provide a first plasma about a first surface location and a second plasma about a second surface location, the first plasma having first ablation parameters and the second plasma having second ablation parameters. The probe has a working end with a thickness below 3 mm and produces a low temperature plasma.

A catheter system for treating a treatment site within or adjacent to a vessel wall or a heart valve includes an energy source, a balloon, an energy guide, and an electrical analyzer assembly. The energy source generates energy. The balloon is positionable substantially adjacent to the treatment site. The balloon has a balloon wall that defines a balloon interior that receives a balloon fluid. The energy guide is configured to receive energy from the energy source and guide the energy into the balloon interior. The electrical analyzer assembly is configured to monitor a balloon condition during use of the catheter system. The electrical analyzer assembly can include a first electrode, a second electrode, and an impedance detector that is electrically coupled to the first electrode and the second electrode. The impedance detector is configured to detect impedance between the first electrode and the second electrode.

An exemplary embodiments of the present disclosure are directed to providing a skin care apparatus using plasma and near-infrared ray designed to provide effects of improving skin and lifting by irradiating plasma and near-infrared ray generated through dual electric generation on skin contacted by a spherical form. Further, the exemplary embodiments of the present disclosures are directed to providing a skin care apparatus using plasma and near-infrared ray that prevents skin contact or dual irradiation, which were used to happen in the conventional side contact structure, with the method of irradiating plasma and near-infrared ray by using dielectric barrier discharge for each of the plasma discharge groove and near-infrared irradiation groove that are different from the conventional contact structure, through a spot contact spherical body structure.

A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed comprising: (a) using a first device to generate smoke, aerosol or vapour from a target in vitro or ex vivo cell population; (b) mass analysing and/or ion mobility analysing said smoke, aerosol or vapour, or ions derived therefrom, in order to obtain spectrometric data; and (c) analysing said spectrometric data in order to identify and/or characterise said target cell population or one or more cells and/or compounds present in said target cell population.

A system for controlling ablation treatment and visualization is disclosed where the system comprises a tissue ablation instrument having one or more deployable stylets and a first electromagnetic sensor and an ultrasound imaging instrument which may be configured to generate an ultrasound imaging plane and further having a second electromagnetic sensor. An electromagnetic field generator may also be included which is configured for placement in proximity to a patient body and which is further configured to generate an output indicative of a position the first and second electromagnetic sensors relative to one another. Also included is a console in communication with the ablation instrument, ultrasound imaging instrument, and electromagnetic field generator, wherein the console is configured to generate a representative image of the tissue ablation instrument oriented relative to the ultrasound imaging plane and an ablation border or cage based upon a deployment position of the one or more stylets.

A method and system for tattoo removal from a subject by exposing tattoo ink particles trapped within the dermis to a cold plasma is described herein. The tattoo removal method and system can be used to remove the tattoo from the skin of the subject being treated. In addition, the method and system described allows for the extraction of the tattoo ink particles, which may have toxic properties, from the subject's body.