The invention is devices and methods to treat benign prostatic hyperplasia (BPH) and associated lower urinary tract symptoms infections (LUTS). The devices are intra-urethral implants placed in a patient in need thereof by minimally invasive procedures, preferably under local anesthesia in an office environment. The devices are sized and designed for atraumatic insertion and expansion within the urethra to engage and retract enlarged prostatic tissue proximate to the urethra that is leading to adverse symptoms associated with BPH. The methods include steps to deploy the implant devices of the invention using a delivery system of the invention and at target prostatic tissue that is visualized during the procedure and yields a reduction in the symptoms of BPH.

Devices and methods are disclosed for managing and/or treating body tissues obstructing a hollow body lumen, including the prostatic lobe tissues obstructing the urethra, for example conditions including benign prostatic hyperplasia (BPH), bladder outlet obstruction (BOO), benign prostatic obstruction (BPO) and associated lower urinary tract symptoms (LUTS). A prostatic implant deployment and delivery system may have a controlled release mechanism, a handle mechanism and an irrigation system. The controlled release mechanism includes a disengageable connection between a pusher member and the prostatic implant with a control member. The handle mechanism includes a plunger for advancing the pusher member and an actuator for withdrawing the control member. The irrigation system may define two fluid paths.

An implant for creating incisions in the tissues surrounding the bladder neck and the urethra of a patient, for relaxing the opening of the bladder, the implant includes a central connector and at least one wire, the wires extend radially outwardly from the center of the central connector, the wires apply continuous pressure on the surrounding tissues, the wires are foldable within an implant sheath for enabling delivery and extraction thereof, the implant is implanted within a restricted location of the urethra for a period of time for creating incisions at the locations where the wires apply pressure on the surrounding tissues.

An implant in which the Lobus medius (median lobe) can be treated in a simple and reliable manner. This is achieved by virtue of the fact that an implant for the treatment of a urinary tract has a wire structure. The wire structure has a loop wire, which can be expanded to form a loop, wherein at least two net wires can be stretched in this loop and the wire structure can be placed around the median lobe.

An implant with which a urinary tract can be treated in a simple and reliable manner is achieved in that a wire structure of an implant can be introduced into the urethra in a folded state with a distal end in the lead. The wire structure is unfolded inside the urethra for the treatment of the tissue. The ischemic pressure of the wires on the surrounding tissue results in denaturation. At least one further device for constricting or cutting into tissue is positioned on the wire structure. This at least one further device is designed in such a way that it exerts a local ischemic pressure on the median lobe in the unfolded state of the implant.

Devices and methods for treating a target site in a body lumen are provided. A medical device includes a stent-like structure including a plurality of scoring and non-scoring filaments interwoven with one another. Generally, the stent-like structure will have more non-scoring filaments than scoring filaments to provide greater structural support and to focus the scoring forces on only a few select areas. The stent-like structure is expanded within the target site to score the target site and to provide temporary structural support while the target site is infused with a therapeutic agent. Such therapeutic agent infusion occurs with the use of a drug eluting or drug coated balloon disposed within the stent-like structure or by occluding the target site and introducing a drug into the occluded target site to sit for a period of time.

The present invention is a skin tag remover which includes a cord formed into a loop at a tag end for placing around a skin tag, a cord housing for receiving a portion of the cord there through and a finger ring attached to a ring end of the cord. Pulling on the finger ring tightens the loop around the skin tag and places the cord into a constricted position so that blood flow is restricted to the skin tag. A blade is included in the cord housing with a plunger that urges the blade downward to sever and detach the cord from the cord housing.

A device for applying a thread loop around a skin tag (26), the device comprising a thread cartridge (10) arranged to be connected to a tool (1) which has a hollow cylindrical handle (2) with a piston (7) which can be run inside the handle, wherein the piston (7 first end (9) which in a base position of the piston connects to an opening (5) in a front end (3) of the handle, where a thumb grip (16) is attached to the piston (7) and via a slot (17) in the handle (2) is arranged accessible from the outside of the handle whereby the piston (7) is displaceable from its base position along the interior of the handle (2), where the piston (7) has a carrier (18) at its first end (9) to which an inner end of said thread cartridge (10) is arranged to be connected, further a thread loop (14) in an outer end of the thread cartridge (10) is arranged to be laid around the skin tag (26), where a displacement of the piston (7) from the base position by means of the thumb grip (16) contracts the thread loop (14) around the skin tag (26) and the inner end of the thread cartridge (10) is arranged to be detached from the carrier (18) when the handle (2) is tilted in relation to the longitudinal direction of the thread cartridge (10), whereby the handle (2) is removed from the thread cartridge (10).

Systems and methods for facilitating the removal of a tissue specimen from a patient are disclosed. The systems include a bag or pouch, a tissue cutter device, a support and a stabilizer. The tissue cutter device includes a passer, a wire, and a handle. The support is an elongated member. The passer is an elongated member configured to be coupled to the support and introduced as a temporary unit into the mouth of the bag or pouch in the patient's body holding the tissue specimen. The wire is attached to the passer. The temporary unit is configured to pass around the tissue specimen and out of the opening in the bag or pouch to carry the wire through that path so that a distal portion of the wire and a proximal portion of the wire are outside the patient's body. Those portions of the wire can be pulled to cut into the tissue specimen. The stabilizer holds the tissue specimen as the wire cuts into it. The bag or pouch includes direction-bearing indicia to facilitate viewing of the methods from within the patient's body.

A system for removing a thrombus. The system includes an expandable device that maintains axially fixed engagement with the thrombus. The expandable device applies a first force to the thrombus according to surrounding vessel size. The expandable device applies a second force to the thrombus according to an increased vessel size to maintain axially fixed engagement.