The disclosure purposes to provide an optical coherence tomography (OCT)-based system for diagnosing a high risk lesion such as a vulnerable atheromatous plaque by using an artificial intelligence model through deep learning. A deep learning-based diagnostic method of diagnosing a high risk lesion of a coronary artery includes: acquiring an OCT image of a coronary artery lesion of a patient; extracting a first feature of a thin cap from the OCT image; setting a region of interest included in the OCT image on a basis of the first feature; and determining whether the region of interest includes a high risk lesion.

A cardiovascular health assessment score, representing a working tissue flow and indicating the dependence on central and peripheral control mechanisms, is generated by the evaluation system and used to support a variety of individualized medicine and health applications. One or more of the individualized medicine and health applications may be implemented as part of the evaluation system and incorporate the cardiovascular health assessment.

A cardiovascular health assessment score, representing a working tissue flow and indicating the dependence on central and peripheral control mechanisms, is generated by an evaluation system and used to support a variety of individualized medicine and health applications. One or more of the individualized medicine and health applications may be implemented as part of the evaluation system and incorporate the cardiovascular health assessment.

Apparatus for rupturing muscle fibres in a lower oesophageal sphincter comprises a balloon catheter. A multi-electrode impedance planimetry measuring system comprising a pair of stimulating electrodes and sensing electrodes is located on the catheter within the balloon for monitoring the diameter of the balloon when the balloon is inflated with a liquid saline solution from a reservoir through a flowmeter under the control of a microprocessor. The microprocessor computes the minimum diameter value from signals read from the sensing electrodes each time the cumulative volume of the liquid saline solution in the balloon increases by a predefined unit volume. The microprocessor computes a curve of a plot of the minimum diameter values against the corresponding cumulative volume values and determines the slope at each computed minimum diameter value. Rupture of the muscle fibres of the sphincter is determined at the point of inflection of the curve.

A curtain airbag device mounting structure includes: a first pillar forming a part of a front pillar and extends substantially along a vehicle height direction; a second pillar forming another part of the front pillar, the second pillar being disposed on a rear side of a vehicle relative to the first pillar at a predetermined distance from the first pillar and extending substantially along the vehicle height direction; a transparent member bridged between the first pillar and the second pillar; and a curtain airbag device including a curtain airbag stored along a roof side rail and the second pillar, the curtain airbag being configured to inflate and deploy in a curtain-like fashion over a side portion of a cabin of the vehicle in case of a collision of the vehicle.

A cardiovascular health assessment score, representing a working tissue flow and indicating the dependence on central and peripheral control mechanisms, is generated by the evaluation system and used to support a variety of individualized medicine and health applications. One or more of the individualized medicine and health applications may be implemented as part of the evaluation system and incorporate the cardiovascular health assessment.

Methods and apparatus are provided for assessing endothelial function in a mammal. In certain embodiments the methods involve using a cuff to apply pressure to an artery in a subject to determine a plurality of baseline values for a parameter related to endothelial function as a function of applied pressure (P.sub.m); b) applying a stimulus to the subject; and applying external pressure P.sub.m to the artery to determine a plurality of stimulus-effected values for the parameter related to endothelial function as a function of applied pressure (P.sub.m); where the baseline values are determined from measurements made when said mammal is not substantially effected by said stimulus and differences in said baseline values and said stimulus-effected values provide a measure of endothelial function in said mammal.

A skin diagnosing device includes an optical unit including: an optical system that uses OCT; an optical mechanism to guide light from the optical unit to skin to scan the skin; a loading device to apply predetermined deformation energy to the skin; a control computation unit to compute tomographic distribution of predetermined status values relating to the skin by controlling driving of the loading device and the optical mechanism and processing optical interference signals output from the optical unit in response to the driving, to compute an evaluation value of the skin based on the tomographic distribution; and a display device to display the evaluation value of the skin. The control computation unit computes the evaluation value by computing mechanical characteristics and a blood flow condition of the skin as the status values and associating the mechanical characteristics and the blood flow condition at a cross-sectional position of the skin.

A skin diagnosing device includes an optical unit including: an optical system that uses OCT; an optical mechanism to guide light from the optical unit to skin to scan the skin; a loading device to apply predetermined deformation energy to the skin; a control computation unit to compute tomographic distribution of predetermined status values relating to the skin by controlling driving of the loading device and the optical mechanism and processing optical interference signals output from the optical unit in response to the driving, to compute an evaluation value of the skin based on the tomographic distribution; and a display device to display the evaluation value of the skin. The control computation unit computes the evaluation value by computing mechanical characteristics and a blood flow condition of the skin as the status values and associating the mechanical characteristics and the blood flow condition at a cross-sectional position of the skin.

A curtain airbag device mounting structure includes: a first pillar forming a part of a front pillar and extends substantially along a vehicle height direction; a second pillar forming another part of the front pillar, the second pillar being disposed on a rear side of a vehicle relative to the first pillar at a predetermined distance from the first pillar and extending substantially along the vehicle height direction; a transparent member bridged between the first pillar and the second pillar; and a curtain airbag device including a curtain airbag stored along a roof side rail and the second pillar, the curtain airbag being configured to inflate and deploy in a curtain-like fashion over a side portion of a cabin of the vehicle in case of a collision of the vehicle.