A wearable biofluid volume and composition system includes a microfluidic flexible fluid capture substrate having a microfluidic channel configured as a sweat collection channel and is configured to be worn on a human body and to collect and analyze biofluid. The microfluidic flexible fluid capture substrate further has a plurality of conductive traces and electrodes. An electronic module is attached to the microfluidic flexible fluid capture substrate and is configured to measure and analyze data from the biofluid collected by the microfluidic flexible fluid capture substrate and to transmit the analyzed data to a smart device.

A wearable sweat sensor for detecting one or more analytes in human sweat comprises an optical module comprising at least one light source and at least one light detector; at least one sensor layer optically coupled to the optical module and having optical absorbance properties that are dependent on the concentration of a target analyte of said one or more analytes; and one or more processors in communication with the optical module. The one or more processors are configured to: cause light from the at least one light source to be transmitted towards, and/or through, the at least one sensor layer; obtain, from the at least one light detector, one or more optical signals reflected and/or transmitted from the at least one sensor layer; and determine, from at least one wavelength component of the one or more optical signals, a target analyte concentration.

A sweat sensor patch of the present disclosure is a sweat sensor patch attached to a skin of a user and used, and includes: an opening formed layer which has a first surface and a second surface which face in opposite directions, and includes an opening penetrating in a thickness direction from the first surface to the second surface; an electrode layer formed on an inner wall surface of the opening; a porous layer which is stacked on the second surface of the opening formed layer and is formed to cover the opening; and a porous pillar which extends in the thickness direction of the opening formed layer within the opening and is connected with the porous layer.

A monitoring patch including a substrate having an adhesive surface and a plurality of sensors disposed in and/or on the substrate. In some embodiments, the plurality of sensors may include one or more sensors arranged to measure oxygen saturation, a lactate sensor, and one or more impedance cardiography electrodes. In some embodiments, the plurality of sensors may include an accelerometer and a strain gauge, and may be free of at least one sensor of a sensor arranged to measure oxygen saturation, a lactate sensor, or an impedance cardiography electrode.

A sweat sensor includes a first conductor and a second conductor that are parallel with one another. The sweat sensor also includes a channel disposed between the first and second conductors. The channel is configured to receive a sample of sweat. A measure of capacitance between the first and second conductors changes based at least partially upon a volume of the sweat in the channel.

A biomarker diagnostic system includes a sensor to collect a sweat sample from a biological subject; a processor operatively connected to the sensor, wherein the processor is configured to perform metabolic and proteomic profiling of biomarkers in the sweat sample. The metabolic and proteomic profile is compared to a predetermined profile of the biomarkers and to determine a physiological status of the biomarkers. The system further includes a feedback unit operatively coupled to the sensor and the processor and configured to output physiological performance data based on the physiological status.

A surface of a vehicle component can be dynamically deformable surface. The dynamically deformable surface can be configured to undergo deformations to dynamically form a dynamic button or other user interface element on demand. The dynamically deformable surface can include one or more biosensors. When a user engages the dynamic button with a portion of the body, the one or more biosensors can acquire user biodata. The user biodata can be used by the vehicle as input for various purposes. For instance, the vehicle can operate as a health-monitoring and/or comfort monitoring system. As a result of these arrangements, buttons and other user interface elements can appear and disappear depending on the need and/or application, providing a cleaner vehicle cockpit interface and greatly expanding the possibilities of where such buttons can be located at and how many things can be controlled by the driver using physical interfaces.

A dry electrode and a physiological multi-parameter monitoring equipment are disclosed. The waterproof dry electrode comprises an encapsulation, extraction electrode and a contact surface layer, wherein the extraction electrode and the contact surface layer are connected with each other and disposed in the encapsulation; the contact surface layer comprises an exposed part and an embedded part encapsulation; the encapsulation comprises flexible silica gel and hard plastic portion, the embedded part being embedded into the hard plastic portion, and the hard plastic portion being packaged in the flexible silica gel. Through the above arrangement in the present invention, the dry electrode can reach a waterproof grade of IPX7, which is higher than living waterproof grade of an ordinary dry electrode. The PMPME can be a patch-type acquisition and monitoring equipment which is convenient for long time wearing and physiological multi-parameter monitoring, with excellent sealing and waterproofness, and the electrode is reusable.

Presented herein are systems and methods for measuring sweat rate of a subject using a wearable system. A sweat rate may be determined automatically based on one or more signals produced by a wetting sensor module in response to a presence of sweat in the wearable system. The one or more signals may be produced using a sweat presence monitoring device, for example comprising two or more electrodes that are operable to make conductance measurements. In some embodiments, sweat drops are periodically collected by the wearable system and individually detected by the wetting sensor module such that the sweat rate is determined based on the periodic detection of the drops. In some embodiments, an energy barrier is used to produce periodic flow of sweat through the wearable device detected by the wetting sensor module such that the sweat rate is determined based on the periodic flow.

A biosensor includes a substrate; a working electrode including a working electrode layer formed on the substrate and an enzyme reaction layer formed on the working electrode layer to cover the working electrode layer; a reference electrode formed on the substrate to be spaced apart from the working electrode; and an insulation barrier rib separating the working electrode and the reference electrode on the substrate. The biosensor has a wide measurement range, excellent sensitivity, and reduced dispersion of measured values.