The present invention generally relates to collecting, determining and/or transmitting information associated with the process of receiving bodily fluid through a device opening and/or delivering substances to a subject. In one aspect, the device includes an information collecting portion and a fluid receiving portion. In another aspect, the two portions are constructed and designed to attach to one another. In one embodiment, actuation of one of the portions causes the other portion to actuate. Methods of time keeping and information transmission are also discussed.

A primer may be used with IV catheter systems. The primer may be positioned along the tubing of an extension set such that the primer divides the IV catheter system into a downstream portion and an upstream portion. The primer may vent air from both the upstream and downstream portions to allow blood to flow up to the primer while also allowing priming solution to flow down to the primer. As a result, the catheter may be inserted into the patient's vasculature without first priming the catheter. Once the air has been vented from the upstream and downstream portions of the IV catheter system, the primer may be actuated to open a fluid pathway through the primer. With the fluid pathway opened, the priming solution may commence flowing towards the patient's vasculature thereby flushing the blood from the IV catheter system.

Provided herein are materials and methods relating to cell-free DNA. In particular, the technology relates to methods and materials for the preparation and handling of blood samples for future use in applications involving cell-free DNA.

A secure specimen sample bottle includes a base container for receiving a specimen. The base container has a plurality of locking protrusions formed along an inner surface of the base receptacle. A bottle includes a lock ring that has an upright spire structure that has a closed top end and the opposing open bottom end including a plurality of flexible fins that are configured to interlockingly mate with the locking protrusions so as to prevent removal of the lock ring relative to the base container upon engagement of the flexible fins to the locking protrusions. A removable cap is coupled to the lock ring.

A cannula insertion system to insert a cannula into a human or animal body, includes: one or more sensors to determine a suitable location for insertion of the cannula, a cannula insertion device configured to insert the cannula into the human or animal body, a cannula insertion device positioning system to support and position the cannula insertion device, and a control device arranged to control the positioning system to position, on the basis of the determined location for insertion of the cannula, the cannula insertion device in a suitable position to insert the cannula into human or animal body, where the cannula insertion system includes a blood collection system to collect blood in one or more blood collection tubes supported by the blood collection system, where the blood collection system is movably arranged to at least partly follow movements of the cannula insertion device.

A cannula insertion system to insert a cannula into a human or animal body, includes: one or more sensors to determine a suitable location for insertion of the cannula, a cannula insertion device configured to insert the cannula into the human or animal body, a cannula insertion device positioning system to support and position the cannula insertion device, and a control device arranged to control the positioning system to position, on the basis of the determined location for insertion of the cannula, the cannula insertion device in a suitable position to insert the cannula into human or animal body, where the cannula insertion system includes a blood collection system to collect blood in one or more blood collection tubes supported by the blood collection system, where the blood collection system is movably arranged to at least partly follow movements of the cannula insertion device.

A device and method for separating serum or plasma from blood cells in a whole blood specimen. The present invention uses a cap with a reservoir, such that blood cells are packed into the cap when the specimen container is centrifuged. When the cap is removed, the blood cells are also removed, and the serum or plasma is left in the specimen tube where it can be readily extracted by a pipette which is able to reach all the way to the bottom of the specimen tube minimizing the dead volume.

A quartz glass container is shown and described herein. The quartz glass container exhibits a low concentration of surface defects on an inner surface of the container. In aspects hereof, the container may have a surface defect density of 50 or fewer surface defects per square centimeter within a 1 cm band centered 1 cm from the base of the container.

A quartz glass container is shown and described herein. The quartz glass container exhibits a low concentration of surface defects on an inner surface of the container. In aspects hereof, the container may have a surface defect density of 50 or fewer surface defects per square centimeter within a 1 cm band centered 1 cm from the base of the container.

Blood sample optimization systems and methods are described that reduce or eliminate contaminates in collected blood samples, which in turn reduces or eliminates false positive readings in blood cultures or other testing of collected blood samples. A blood sample optimization system can include a blood sequestration device located between a patient needle and a sample needle. The blood sequestration device can include a sequestration chamber for sequestering an initial, potentially contaminated aliquot of blood, and may further include a sampling channel that bypasses the sequestration chamber to convey likely uncontaminated blood between the patient needle and the sample needle after the initial aliquot of blood is sequestered in the sequestration chamber.