In an embodiment, there is provided an apparatus. The apparatus includes an analog front end for biosignal acquisition. The analog front end includes an instrumentation amplifier and a reconfigurable filter. The instrumentation amplifier is configured to receive a biosignal and includes a super class-AB output stage. The reconfigurable filter is coupled to an output of the instrumentation amplifier. The reconfigurable filter has a selectable gain and an adjustable bandwidth. The bandwidth is adjusted based, at least in part, on a duty cycle of a clock signal.

In an embodiment, there is provided an apparatus. The apparatus includes an analog front end for biosignal acquisition. The analog front end includes an instrumentation amplifier and a reconfigurable filter. The instrumentation amplifier is configured to receive a biosignal and includes a super class-AB output stage. The reconfigurable filter is coupled to an output of the instrumentation amplifier. The reconfigurable filter has a selectable gain and an adjustable bandwidth. The bandwidth is adjusted based, at least in part, on a duty cycle of a clock signal.

A system may include a stimulator, sensing circuitry and a controller. The stimulator may be operably connected to at least one stimulation electrode, and configured to deliver an electrical waveform for an electrical therapy using the at least one stimulation electrode. The sensing circuitry may be operably connected to at least one sensing electrode, and configured to sense electrical potentials that are evoked by the electrical waveform to provide sensed evoked signals. The controller may be operably connected to the stimulator and the sensing circuitry. The controller may be configured to automatically define a sampling window, sample the sensed evoked potentials during the sampling window to provide sampled values, detect at least one feature from the sampled values, and automatically provide feedback for closed-loop control of the electrical therapy based on the at least one feature.

An electric signal transmission device including an electrode 11, disposed to be opposed to an electrogenic cell, and for sending and receiving electric signals to and from the electrogenic cell via the electrode 11.

A neurostimulation system comprises at least one stimulation electrode configured to deliver an electrical stimulus to neural tissue and at least one measurement electrode configured to record a neural recording of a response of the neural tissue to the stimulus. A processor is configured to assess the neural recording to produce a measure of postsynaptic activation.

The purpose of the present invention is to provide a technique whereby multiple projection targets are efficiently identified from multiple neurons in multiple brain areas with the use of multis-point light stimulation. An acquisition unit 52 acquires spike signals generated from multiple neurons existing in the vicinity of two or more recording sites. A stimulation control unit 51 selects one projection target candidate from two or more candidates in accordance with a definite system on the basis of the spike signals and then determines irradiation timing of light stimulation. Upon the light stimulation, a management unit 53 acquires the spike signals in all of the recording sites within a definite period of time before or after the light stimulation, while dividing the spike signals into anti responses and collision responses. An anti response management unit 81 acquires and manages information relating to the anti responses. A collision response management unit 82 acquires and manages information relating to the collision responses. A priority control section 54 corrects and determines priority depending on the anti response information and the collision response information.

The purpose of the present invention is to provide a technique whereby multiple projection targets are efficiently identified from multiple neurons in multiple brain areas with the use of multis-point light stimulation. An acquisition unit 52 acquires spike signals generated from multiple neurons existing in the vicinity of two or more recording sites. A stimulation control unit 51 selects one projection target candidate from two or more candidates in accordance with a definite system on the basis of the spike signals and then determines irradiation timing of light stimulation. Upon the light stimulation, a management unit 53 acquires the spike signals in all of the recording sites within a definite period of time before or after the light stimulation, while dividing the spike signals into anti responses and collision responses. An anti response management unit 81 acquires and manages information relating to the anti responses. A collision response management unit 82 acquires and manages information relating to the collision responses. A priority control section 54 corrects and determines priority depending on the anti response information and the collision response information.

A system for recording, processing, and monitoring biosignals is provided, the system being configured to suspend data acquisition whenever an electric surgical tool or other generator of high frequency interference is in use. Such a system may protect the hardware of the system and reduce or eliminate the acquisition of distorted signals. The system of some embodiments includes an amplifier system configured to detect the presence of high frequency interference. Related methods are also disclosed.

A system for recording, processing, and monitoring biosignals is provided, the system being configured to suspend data acquisition whenever an electric surgical tool or other generator of high frequency interference is in use. Such a system may protect the hardware of the system and reduce or eliminate the acquisition of distorted signals. The system of some embodiments includes an amplifier system configured to detect the presence of high frequency interference. Related methods are also disclosed.

A device includes a sensor signal input node and a high-pass filter stage. The high-pass filter stage includes an operational amplifier and a feedback integrator. The operational amplifier includes an input node coupled to the sensor signal input node. The feedback integrator is coupled between an output node of the operational amplifier and the input node of the operational amplifier to set a high-pass pole frequency of the high-pass filter stage.