Systems and methods for enhancing infection detection and monitoring through decomposed physiological data are disclosed. An example method includes receiving, from a wearable device of a user, physiological data of the user and decomposing the physiological data, by applying a heart rate algorithm, to generate one or more physiological parameters. The example method further includes analyzing, by applying the heart rate algorithm, the one or more physiological parameters to output a period classification, and determining whether or not the period classification is indicative of an infection. The example method further includes, responsive to determining that the period classification is indicative of the infection, displaying, in a user interface, a warning to the user that indicates the infection, and receiving, from the wearable device of the user, additional physiological data of the user to monitor the infection.

Arrangements and methods are provided for obtaining information associated with an anatomical sample. For example, at least one first electro-magnetic radiation can be provided to the anatomical sample so as to generate at least one acoustic wave in the anatomical sample. At least one second electro-magnetic radiation can be produced based on the acoustic wave. At least one portion of at least one second electro-magnetic radiation can be provided so as to determine information associated with at least one portion of the anatomical sample. In addition, the information based on data associated with the second electro-magnetic radiation can be analyzed. The first electro-magnetic radiation may include at least one first magnitude and at least one first frequency. The second electro-magnetic radiation can include at least one second magnitude and at least one second frequency. The data may relate to a first difference between the first and second magnitudes and/or a second difference between the first and second frequencies. The second difference may be approximately between −100 GHz and 100 GHz, excluding zero.

A portable system is disclosed for collecting a sample from exhaled breath of a subject. Drug substance in the exhaled breath are detected or determined. The sample is collected for further analysis using mass-spectroscopy. The system comprises a sampling unit and a housing arranged to hold the sampling unit, the sampling unit is adapted to collect non-volatile and volatile compounds of the at least one drug substance from the exhaled breath from the subject. The housing has at least one inlet for the subject to exhale into the housing to the sampling unit and at least one outlet for the exhaled breath to exit through.

An MR Spectroscopy (MRS) system and approach is provided for measuring spectral information corresponding with propionic acid (PA), either alone or in combination with other measurements corresponding with other chemicals, to diagnose and/or monitor at least one of bacterial infection, such as associated with P. acnes, or conditions related thereto such as nociceptive pain associated with tissue acidity. An interfacing DDD-MRS signal processor receives output signals to produce a post-processed spectrum, with spectral regions corresponding with certain chemicals, including PA, then measured as biomarkers. A diagnostic processor derives a diagnostic value for each disc, and performs certain normalizations, based upon ratios of the spectral regions related to chemicals implicated in degenerative painful tissue pathology, such as PA and hypoxia markers of lactic acid (LA) and alanine (AL), and structural chemicals of proteoglycan (PG) and collagen or carbohydrate (CA).

Apparatus and methods are described including identifying that a subject suffers from sleep apnea. Positive airway pressure (PAP) is applied to the subject via a mask placed on a face of the subject. A respiratory-related parameter of the subject is sensed, while the mask is on the face of the subject, and a need of the subject for respiratory support is assessed, responsively to the respiratory-related parameter. In accordance with the assessed need, the mask is configured to regulate the PAP provided to the subject's face. Other applications are also described.

An active implantable medical device (IMD) which, in operation: repeatedly senses a body temperature of a person having the IMD implanted therein; stores the sensed body temperature values; repeatedly senses a cardiac physiologic parameter of the person; stores the sensed cardiac physiologic parameter values; determines whether one of the body temperature values exceeds a predefined body temperature threshold; if an excess is determined, the IMD: determines whether one of the cardiac physiologic parameter values exceeds a predefined cardiac physiologic parameter threshold, wherein the one cardiac physiologic parameter value is determined in the same time period as the one body temperature value exceeding the body temperature threshold; classifies an infection of the person as a local infection if the one cardiac physiologic parameter value does not exceed the threshold; or classifies an infection of the person as a systemic infection if the one cardiac physiologic parameter value exceeds the threshold.

The invention concerns an Interoperability Environment comprising: a core software engine comprising means to collect and transfer electronic data from any number of sources including medical devices, clinical information systems, hospital information systems, a means to apply rules to improve compliance with hospital approved protocols, standards and guidances, a means to update all subsystems using any given parameter when the parameter is updated in the official recognized source of truth for that parameter, a means to populate the CIS with all required patient information, while at the same time maintaining all quality and process control data in a format supporting advanced analytics separate from the CIS data, a means to communicate notifications to any number of remote electronic devices without limitation of platform and comprising a hardware eco system comprising means to collect, translate, store and send electronic data to the core software engine for any electronic source via communication methods including but not limited to LAN, Serial, Wi Fi, Wireless, etc.

Embodiments of the present technology include a method for testing a blood sample for sepsis. The method may include receiving a blood sample from an individual. The method may also include executing an instruction to analyze the blood sample for sepsis. In addition, the method may include measuring values of a set of characteristics in the blood sample. The set of characteristics being determined prior to measuring the values. The method may further include analyzing the values of the set of characteristics to produce a representation of a suspicion of sepsis. In addition, the method may include displaying the representation. Embodiments also include systems for testing blood sample for sepsis.

An artificial intelligence assisted medical diagnosis method for a sepsis is proposed. A database reading step is performed to read a sepsis database and at least one database to be tested of a storing unit. The sepsis database includes a plurality of sepsis data, and the at least one database to be tested includes a plurality of data to be tested. A data table creating step is performed to create a sepsis data table according to the sepsis data, and create a data table to be tested according to the data to be tested. A model training step is performed to train the sepsis data table according to a K-fold cross-validation and a machine learning algorithm to generate a sepsis diagnosis model. A sepsis predicting step is performed to input the data table to be tested into the sepsis diagnosis model to calculate a sepsis prediction result.

A wirelessly triggered device for implantation in vivo is disclosed herein. In a described embodiment, the wirelessly triggered device comprises an electrically conductive suture; and an electronic circuit coated with a biocompatible encapsulating material and communicatively coupled to the electrically conductive suture, the electronic circuit arranged to convert a received wireless triggering signal into an electrical signal for passing through the conductive suture. A reader for use with the device and an electrically conductive surgical thread is also disclosed, among other aspects.