A wearable antenna is described, for wirelessly receiving sensor data generated by an implantable sensor device implanted in a uterus, the wearable antenna, in use, extending around the waist of the wearer's body, and having a downwardly extending portion for location at the front of the wearer's body. In this way, an improved electromagnetic interaction between the wearable antenna and the implantable sensor can be achieved. Further, the wearable antenna may have an undulating shape around at least a portion of the wearer's waist, to permit expansion and contraction of the wearable antenna about the wearer's waist.

Methods for evaluating micrometastases in a tissue region of a subject are described. The methods include administering to the subject a detectably effective amount of a tumor-targeted photoactivatable immunoconjugate; allowing a sufficient amount of time for the tumor-targeted photoactivatable immunoconjugate to enter micrometastases in the tissue region; illuminating the tumor-targeted photoactivatable immunoconjugate; obtaining an image of the tissue region of the subject using a fluorescent imaging device, and evaluating the micrometastases in the tissue region by conducting algorithmic analysis of the image. Methods of treating micrometastases in a tissue region of a subject are also described.

The present invention relates to a method for contactlessly measuring the amount of menstrual blood in a menstrual cup. The amount of menstrual blood that has been stored in a menstrual cup can be simply measured by using a contactless sensor means, thereby enabling the user to periodically check the amount of menstrual blood. This enables early detection and treatment of uterine fibroid, which may even lead to hysterectomy.

The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a pteroyl ligand that binds to a target receptor protein, ii) a dye molecule, and iii) a linker molecule that comprises an amino acid or derivative thereof. The disclosure further describes methods and compositions for incorporating the compounds as used for the targeted imaging of tumors. Conjugation of the amino acid linking groups increase specificity and detection of the compound. Methods and compositions for use thereof in diagnostic imaging are contemplated.

A tissue disorder monitoring system includes at least two electrodes constructed and arranged to obtain analog electrical signals from a patient. An amplifier amplifies the analog electrical signals. Filter structure filters the amplified analog electrical signal. An A/D converter converts the amplified and filtered analog electrical signals to digitized electrical signals. A microprocessor circuit is constructed and arranged to execute an application that analyzes the digitized electrical signals to identify and to determine treatment data including a specific location and/or propagation of disordered tissue within the patient. A transmitter transmits data in a wireless manner. A power supply powers the device. A method locating disordered tissue in a patient is also disclosed.

An intra-uterine monitoring system is described. The system comprises an implantable sensor device, shaped and dimensioned for implantation in a uterus for measuring conditions within the uterus to generate sensor data, and a wearable receiver device, for wirelessly receiving the sensor data generated by the implantable sensor device. In this way, real-time, in-vivo monitoring of the intra-uterine environment can be performed. The implantable sensor device can be kept small and simple, requiring only the mechanical and electronic structures necessary to take sensor measurements and transmit those to the receiver device. By making the receiver device wearable, it can be kept in relatively close proximity to the implantable sensor device on a long-term basis, making regular monitoring viable.

An optical measurement system is provided, which includes a light source device, a fiber module, an optical detection device and a processing circuit. The light source device is configured to generate light to illuminate a target tissue area and a reference tissue area of a human body. The fiber module is configured to direct and transmit the light to illuminate the target tissue area and the reference tissue area and receive response beams from the target tissue area and the reference tissue area. The optical detection device is configured to detect the response beams from the target tissue area to obtain the target spectrum signal and detect the response beams from the reference tissue area to obtain a reference spectrum signal. The processing circuit configured to calculate a health status parameter of the target tissue area according to the target spectrum signal and reference spectrum signal.

[Problem] To provide a method for acquisition of data able to serve as an index for determining the likelihood that an ovarian endometriosis cyst is cancerous. [Solution] This data acquisition method for determining the likelihood that an ovarian endometriosis cyst is cancerous includes an iron concentration measurement step for measuring the iron concentration in the cystic fluid of the ovarian endometriosis cyst. This diagnostic device for diagnosing the likelihood that an ovarian endometriosis cyst is cancerous is provided, at a minimum, with an iron concentration measurement unit for measuring the iron concentration in the cystic fluid of the ovarian endometriosis cyst.

An interactive treatment mapping and planning system enables a user to more quickly, thoroughly, and efficiently aggregate fibroid and/or treatment information from a user and/or one or more sets of databases, construct a fibroid map providing a visual representation of the aggregated fibroid information, generate information from the aggregated information about the fibroid to be treated and/or treatment procedure, develop a treatment plan based on the fibroid and/or treatment procedure information, provide real-time information gathered from treatment devices during the treatment procedure, and allow the user to interact with the treatment data.

Photoacoustic and/or acousto-optical techniques may be used to transabdominally perform fetal oximetry and/or trans-abdominal fetal pulse oximetry. In some cases, a composite acoustic signal that has emanated from an abdomen of a pregnant mammal may be received by a processor from, for example, an ultrasonic detector and/or microphone positioned on, or near, a pregnant mammal's abdomen and the composite acoustic signal may result from an optical signal incident on the pregnant mammal's abdomen and a fetus contained therein. A portion of the composite acoustic signal that was incident on the fetus may be isolated from the composite acoustic signal and then analyzed to determine a fetal hemoglobin oxygen saturation level and/or a fetal tissue oxygen saturation level.