A system for determining a treatment regimen for chronic pelvic pain (CPP) includes an electromyography (EMG) probe including electrodes. Each electrode detects pelvic floor muscle activity. An EMG sensor array includes bipolar EMG sensors configured to detect muscle activity of muscles associated with or supporting the pelvic floor muscles. An EMG amplifier is in communication with the EMG probe or the EMG sensor array. The EMG amplifier includes a plurality of input channels. Each input channel receives data of muscle activity in the pelvic floor muscles or the muscles associated with or supporting the pelvic floor muscles from the EMG probe or the EMG sensor array. A processor of a computer performs muscle network analysis using the data of muscle activity in the pelvic floor muscles or the muscles associated with or supporting the pelvic floor muscles. A treatment regimen for CPP is recommended based on the muscle network analysis.

A vaginal insert device and method of use for improving and preventing symptoms associated with pelvic organ prolapse and urinary and/or fecal incontinence, administer medication or topical treatment, and/or collect a sample when the device is inserted, or any combination thereof. The vaginal insert device may be cone-shaped, may have a removal portion, may have external ridges, may have internal ribs, may have an open or closed top, or combinations thereof. The device may include cavities, diagnostic devices, and/or microchips.

The present invention relates to the diagnosis and treatment of pelvic floor prolapse. The diagnosis and treatment may involve the use of a multiple sensor-enabled device for vaginal insertion capable of providing real-time data regarding the pa -tient’s physiology, the position and movement of the urethra, and the muscular strength of the patient’s vagina and pelvic floor. The methods and devices of the invention may also be useful to addressing other medical issues, including urinary incontinence, sexual health, and fecal incontinence, as well as facilitate patient home wellness activities.

A glove-mountable system for pelvic floor muscle (PFM) examination includes a first flexible member including a force sensor configured to detect a force applied to a PFM of a patient by a user. A second flexible member includes an electromyography (EMG) electrode, a stimulation electrode, and a 3-D digitization probe. The second flexible member is stacked on the first flexible member and each flexible member is secured to an examination glove. An actuation button is actuated by the user when at least one point of interest is detected in at least on PFM. A computer including a processor and a memory is in communication with the first flexible member, the second flexible member and the actuation button. The computer generates a 3-D map of a plurality of PFMs of the patient based on data received from the first flexible member, the second flexible member and the actuation button.

A pelvic floor contraction detection system and method to evaluate pelvic floor muscle (PFM) exercise performed by a user are disclosed. The contraction detection system comprises a probe adapted to position within a pelvic cavity of the user, a data processing module, and a user interface. The probe comprises two or more sections. Each section is filled with a group of electronic sensors. The first and second sections are seated in contact with tissues of the pelvic cavity. The first and second groups of sensors are configured to detect pressure applied by the internal vaginal surface on the surface of the first and second sections of the probe respectively. The data processing module is in communication with the first and second groups of sensors and configured to calculate a number that is interpreted as the “quality of the contraction”. The data processing module determines the incorrect pelvic floor muscle contraction and notifies the user via a user interface.

A system for diagnosing and quantifying an organ prolapse includes a first manometry catheter configured for insertion within a first organ of the pelvic floor. The first manometry catheter includes an inflatable balloon configured to support a series of first sensors disposed along a length thereof and operably coupled to an image display for displaying a first image thereon relating to the first organ. One or more additional manometry catheters are configured for insertion within one or more respective additional organs. The additional manometry catheters include inflatable balloons configured to support corresponding additional sensors along a length thereof. The additional sensors are operably coupled to the image display for displaying one or more additional images thereon relating to the one or more additional organs. The first image and the one or more additional images being simultaneously displayed on the image display for diagnostic and quantification purposes.

The present invention features a method for automated image-based prediction of physiologic and pathologic conditions of a vaginal wall of a patient using optical coherence tomography. In some embodiments, the method may comprise capturing, by a functional optical coherence tomography imaging probe, one or more images of the vaginal wall. The method may further comprise constructing a computing device a visualization of the vaginal wall, discretizing the visualization of the vaginal wall in to a discrete model, measuring a plurality of objective attributes from the discrete model, generating, based on the plurality of objective attributes, a Vaginal Health Index (VHI), generating an associated risk value based on the VHI and a plurality of patient attributes, reconstructing the visualization of the vaginal wall based on the associated risk value, and mapping the associated risk value to the visualization of the vaginal wall such that one or more at-risk areas are highlighted.

The present disclosure provides systems, methods, devices, and kits for analysis of vaginal biological samples. A device for the analysis of vaginal biological samples can include a sample collector, an extractor, and an assay cartridge. A method for the analysis of vaginal biological samples can include detecting the presence or absence of a pathology, a disease, an immune disorder, a reproductive disorder of a subject. The method may further comprise preserving, storing, or transporting the vaginal biological samples. A kit for the analysis of vaginal biological samples can include probe, reagents and instructions for detecting a nucleic acid in the vaginal biological samples.

A probe includes an insertion portion insertable into a body organ, a projecting portion being exposed to an outside of a body after the insertion portion is inserted into the body organ, a device mounting area onto which an external-device coupler is removably mountable, and sensing electrodes provided on the insertion portion and the device mounting area. When the insertion portion is inserted into the body organ, the sensing electrodes detect a biosignal and become conductive with coupling electrodes of the external-device coupler mounted onto the device mounting area. The probe is an electromyograph probe that detects a biosignal measurable by an electromyograph. The insertion portion and the projecting portion of the probe may be integrated or separate from each other. Both of the insertion portion and the projecting portion or only the insertion portion may be disposable.

A device for measuring contractions and/or relaxation of one or more muscles of a body cavity, the device having a hollow body which is for positioning in the body cavity and which is covered by a coating made of or having a biocompatible material, the body being formed of two half-shells which are each physically connected, permanently and continuously during the use of the device, with the aid of non-compressible or deformable connecting means, to at least one pressure sensor, or part of the pressure sensor, arranged in the body. Also, a method for measuring the contraction and/or relaxation of the muscles of a body cavity, a method for monitoring the contractions and/or relaxation of the muscles, and a method for exercising these muscles.