A scaffold comprised of a plurality of PLLA layers, which may include stem cells, for regenerating bone or tissue. The PLLA layers are separated by a plurality of hydrogel layers. The PLLA layers comprise a nanofiber mesh having a piezoelectric constant to apply an electrical charge to the bone or tissue upon application of ultrasound energy.

A scaffold comprised of a plurality of PLLA layers, which may include stem cells, for regenerating bone or tissue. The PLLA layers are separated by a plurality of hydrogel layers. The PLLA layers comprise a nanofiber mesh having a piezoelectric constant to apply an electrical charge to the bone or tissue upon application of ultrasound energy.

Methods and systems of osteoarthritis treatment. One method includes providing a cartilage hydrogel, the cartilage hydrogel including piezoelectric nano-fibers of Poly-L-lactide (PLLA). The method also includes injecting the cartilage hydrogel into a cartilage defect. The method also includes applying an ultrasonic treatment to the cartilage defect. The method also includes, in response to applying the ultrasonic treatment to the cartilage defect, converting a mechanical impact of the ultrasonic treatment into an electrical charge from the piezoelectric nano-fibers of PLLA and providing, in response to the electrical charge from the piezoelectric nano-fibers of PLLA, chondrogenesis differentiation for cartilage regeneration for the cartilage defect.

An interbody implant to be introduced into a variety of target sites for accelerating bone ossification, for example into a space between two adjacent vertebrae. The interbody implant includes a first bone contacting surface, a second bone contacting surface, a body defined between the first and second bone contacting surfaces, and a plurality of resonators. Mechanical waves, e.g., low intensity pulsed ultrasound waves, may be transmitted to the location of the implant, causing the resonators to resonate and accelerate bone ossification.

A dental device includes a mouthpiece configured to sit against occlusal surfaces of a patient's teeth and a motor connected to the mouthpiece. The motor is configured to vibrate the mouthpiece at a frequency between 60 and 120 Hz and an acceleration between 0.03G and 0.06G such that the mouthpiece places an axial vibratory force on the occlusal surfaces.

A scaffold comprised of a plurality of PLLA layers, which may include stem cells, for regenerating bone or tissue. The PLLA layers are separated by a plurality of hydrogel layers. The PLLA layers comprise a nanofiber mesh having a piezoelectric constant to apply an electrical charge to the bone or tissue upon application of ultrasound energy.

Embodiments of the present disclosure are directed to apparatuses and methods for pre-conditioning an extraction site for dental implantation. In one implementation, a method for pre-conditioning an extraction site for dental implantation includes providing a vibrational dental device configured to vibrate at a frequency higher than about 20 Hz. The method further includes providing instructions for mechanically vibrating, using the vibrational dental device, a tooth at the extraction site for about a predetermined period of time daily over a treatment period before extracting the tooth. The mechanical vibration may prepare the extraction site to be in a healthier condition for receiving an implant.

Discloses is a system for the wireless transmission of energy and/or signals between spatially-separated regions with no electrically-conductive connection, the conversion of energy and/or signals into other forms of energy and/or forms of signal, and the application and/or detection of same in at least one peripheral region of said system. The system allows a wireless transmission of energy between at least two spatially-separated regions without an electrically-conductive connection, energy being supplied to at least one of these regions, transmitted to at least one additional region in a wireless manner, converted on demand into other forms of energy, and applied in a peripheral region of said system. Signals can be transmitted at the same time as energy is being transmitted.

Discloses is a system for the wireless transmission of energy and/or signals between spatially-separated regions with no electrically-conductive connection, the conversion of energy and/or signals into other forms of energy and/or forms of signal, and the application and/or detection of same in at least one peripheral region of said system. The system allows a wireless transmission of energy between at least two spatially-separated regions without an electrically-conductive connection, energy being supplied to at least one of these regions, transmitted to at least one additional region in a wireless manner, converted on demand into other forms of energy, and applied in a peripheral region of said system. Signals can be transmitted at the same time as energy is being transmitted.