Adult autologous stem cells cultured on a porous, three-dimensional tissue scaffold-implant for bone regeneration by the use of a hyaluronan and/or dexamethasone to accelerate bone healing alone or in combination with recombinant growth factors or transfected osteogenic genes. The scaffold-implant may be machined into a custom-shaped three-dimensional cell culture system for support of cell growth, reservoir for peptides, recombinant growth factors, cytokines and antineoplastic drugs in the presence of a hyaluronan and/or dexamethasone alone or in combination with growth factors or transfected osteogenic genes, to be assembled ex vivo in a tissue incubator for implantation into bone tissue.

Disclosed is directed to a method for restoring bone in an animal comprising: accessing a site to be restored; loading a syringe body with a flowable bone graft material; mating the syringe body with a delivery tube; positioning the delivery tube at the site to be restored; using a syringe piston to advance the said material into the delivery tube; using the syringe piston or a plunger that mates with the delivery tube after removal of the syringe body to deliver the bone graft to the site at a force of less than 50 lbs. extrusion force; wherein said material is at least 75% porous with a mineral to polymer ratio of 80:20.

Spinal tissue distraction devices that include a member which has a pre-deployed configuration for insertion between tissue layers and a deployed configuration in which the member, by change of configuration, forms a support structure for separating and supporting layers of spinal tissue.

A tunable implant, system, and method enables a tunable implant to be adjusted within a patient. The tunable implant includes a securing mechanism to secure the implant in the patient, a actuation portion that enables the implant to move and an adjustment portion that permits adjustment of the implant after the implant has been positioned within the patient. The method of adjusting the tunable implant includes analyzing the operation of the implant, determining if any adjustments are necessary and adjusting the implant to improve implant performance. The implant system includes both the tunable implant and a telemetric system that is operable to telemetrically receive data from the tunable implant where the data is used to determine if adjustment of the tunable implant is necessary. The system also includes an instrument assembly that is used for performing spinal surgery where the instrument assembly includes a mounting platform and a jig.

A humeral implant component connectable to another humeral implant component, the humeral implant component comprising: a longitudinal axis, a first end and a second end, the first end and the second end opposing each other along the longitudinal axis of the humeral implant component, and an interface part for connecting the humeral implant component to the other humeral implant component, wherein the interface part is tapered along the longitudinal axis in a direction from the second end to the first end, the interface part being engageable with a tapered interface part of the other humeral implant component to form a tapered connection between the humeral implant component and the other humeral implant component, wherein the humeral implant component further comprises a through hole extending along the longitudinal axis for locking the tapered connection by a longitudinal fastener.

The disclosure relates to a replacement member for a shoulder joint replacement comprising an attachment face on one side of the member, a concave joint surface on a side of the replacement member opposite to the side of the attachment face, and a circumferential face connecting the attachment face and the joint surface. A portion of the concave joint surface is connected to at least a portion of the circumferential face via a chamfered or rounded edge.

The present invention is directed to a hinge joint implant (40) configured to fit in a joint cavity and which can comprise, when in situ, an at least hemi-spherocylindrical configuration, and further a hinge joint implant configured to fit in a joint cavity wherein the implant can extend around the sides of a joint component which may be a bone and/or cartilage. The invention further provides the use of a hinge joint implant according for treating arthritis, and/or torn cartilage, and a method for manufacturing a hinge joint implant from one or more pieces.

A tibial implant includes one or more stiffness-modifying features to reduce the stiffness of one or more sections of the tibial implant. The stiffness-modifying features may include slots, recesses, or passageways defined in various locations of the tibial implant to selectively reduce the stiffness of a tibial insert and/or tibial base of the tibial implant.

An anatomy-specific implant for neuroplastic surgery. The implant includes a soft tissue implant component designed within and adapted to replace or restore missing soft tissue in a skull, joint or spine of the patient, wherein the soft tissue implant component is adapted to be coupled by an interdigitated connection to a rigid component. The rigid component can be a skull implant adapted to replace missing cranial or vertebral bone, or healthy cranial or vertebral bone, either of which can have downward extending catheters for medicinal brain or spinal cord infusion to help bypass the blood-brain barrier via multiphase flow. The soft tissue implant may include a functional component having neurotechnologies such as MRI-lucent pumps, Bluetooth connection systems, refillable diaphragms, remote imaging devices, wireless charging capabilities, and/or informative biosensors. The soft tissue implant component may be interchangeable with another soft tissue implant component in plug-and-play fashion.

A vertebral body system and method having a polyaxial fastener receiving member, adjustable width plates and a pedicle screw having a pedicle threaded portion and a threaded portion for fastening to the vertebral body.