A thermal device includes an inflatable non-perforated blanket, a conduit structure, and a recirculating assembly. The inflatable non-perforated blanket is configured to transport warm air internally. The conduit structure is configured to provide conduit to transport the warm air externally to the inflatable non-perforated blanket. The recirculating assembly is configured to inflate the inflatable non-perforated blanket with the warm air and: (1) to cause the warm air to flow from the first port to the second port in a first direction, and (2) to recirculate the warm air through the conduit structure to flow from the second port to the first port in the first direction. The inflatable non-perforated blanket includes first and second sheets. The first sheet faces ambient air and has a first thermal conductivity. The second sheet faces the subject body and has a second thermal conductivity higher than the first thermal conductivity.

A method and apparatus for manipulating a temperature set-point of a human or homeothermic-animal for increasing or decreasing the body temperature above or below the prevailing body temperature for therapeutic purposes. The method includes the steps of warming or cooling sphenoid sinuses externally resulting in manipulation of the temperature of the pituitary gland which in turn results in manipulation of the body-temperature set-point and the body temperature manipulates accordingly to the new temperature set-point. A heat exchange medium can be used to warm or cool sphenoid sinuses and thus the pituitary gland. The heat exchange fluid can be liquid, or gas maintained at a predetermined temperature. Alternatively, a temperature-controlled probe can be used that upon contact with the sphenoid sinuses provides for the heat exchange.

A thermal device includes an inflatable non-perforated blanket, a conduit structure, and a recirculating assembly. The inflatable non-perforated blanket is configured to transport warm air internally. The conduit structure is configured to provide conduit to transport the warm air externally to the inflatable non-perforated blanket. The recirculating assembly is configured to inflate the inflatable non-perforated blanket with the warm air and: (1) to cause the warm air to flow from the first port to the second port in a first direction, and (2) to recirculate the warm air through the conduit structure to flow from the second port to the first port in the first direction. The inflatable non-perforated blanket includes first and second sheets. The first sheet faces ambient air and has a first thermal conductivity. The second sheet faces the subject body and has a second thermal conductivity higher than the first thermal conductivity.

The present invention provides a method and device for non-invasive anatomical and systemic cooling, fluid removal and/or energy removal. The method and device provide for removal of fluid and cooling of various bodily fluid-containing spaces or surfaces, such as mucus-containing spaces or surfaces via delivery of a dry fluid not including a coolant into or upon the mucus-containing space or surface. Exposure of such mucus to the dry fluid results in evaporation of body fluid, removal of energy, cooling of the anatomical feature, and systemic cooling. In this fashion, therapeutic hypothermia may be achieved to provide for neuroprotection of various organs after ischemic insult, such the brain after cardiac arrest. Similarly, excess fluid removal may be achieved for treatment of cardiogenic shock or other conditions that cause significant fluid build-up, especially in cases of compromised renal function. Additionally, the invention may be used to reduce fever, and other conditions where removal of heat, energy and/or water are beneficial.

An apparatus and method for providing heat exchange in the lungs of the mammal during partial liquid ventilation are provided. The apparatus and method can control delivery and removal of partial liquid ventilation to the lungs of a mammal by responding to pressure change in the lungs to minimize danger of causing barotrauma to the patient.

A steam room for sanitizing people's external body parts and clothes, but also their breathing airways and respiratory tract, to reduce viral load and thereby mitigate the likelihood of spreading or contracting Viral contamination. Steam room has precise temperature and relative humidity control of a heater and mist generator, in which the mist water molecules contain an accurate concentration of a Chlorine or Ethanol based disinfectant, so that the water vapor or combined air/water mixture in the room that comes in contact with the sanitized person reaches but does not surpass the globally permitted concentration of free Chlorine for swimming pools, dressing rooms and spas. The room has thermally isolated quick doors allowing rapid entry and exit, and the signaling to guide the person when to enter, stay and breath, and exit, in the most suitable timing profile for the application.

Methods for cerebral cooling are described. Cooling assemblies include elongate tubular members, a reservoir containing a pressurized fluid, and a manifold connecting the reservoir and elongate tubular members. After insertion of the elongate tubular members into the patient's nostrils, a pressurized fluid is delivered onto a surface of the patient's nasal cavity through a plurality of ports in the elongate tubular members. The delivery of the fluid causes cooling by direct heat transfer through the nasopharynx and hematogenous cooling through the carotids and the Circle of Willis.

The present invention provides a method and device for non-invasive anatomical and systemic cooling, fluid removal and/or energy removal. The present invention provides for removal of fluid and cooling of various bodily fluid-containing spaces or surfaces, such as mucus-containing spaces or surfaces via delivery of a dry fluid not including a coolant into or upon the mucus-containing space or surface. Exposure of mucus to the dry fluid yields evaporation of body fluid, removal of energy, cooling of the anatomical feature, and systemic cooling. Therefore, therapeutic hypothermia may be achieved for neuroprotection of various organs after ischemic insult, like the brain after cardiac arrest. Similarly, excess fluid removal is achievable for treatment of cardiogenic shock or other conditions that cause significant fluid build-up, especially in cases of compromised renal function. Additionally, the invention may be used to reduce fever, and other conditions where removal of heat, energy and/or water are beneficial.

Embodiments of the invention provide apparatus, systems and method for introducing fluids into a body cavity for treatment. One embodiment provides an apparatus for treating a patient including an access device for insertion into the peritoneal cavity of the patient including an infusion member in a lumen of the access device. An oxygenated solution may be infused and removed into and out of the cavity via the infusion member.

An apparatus and method for aspirating, irrigating and/or cleansing wounds is provided. The apparatus and method include one or more of the following: simultaneous aspiration and irrigation of the wound, supplying of thermal energy to fluid circulated through the wound; supplying physiologically active agents to the wound; a biodegradable scaffold in contact with the wound bed; and application of stress or flow stress to the wound bed.