An aerosol spray device includes a container having first and second fluid reservoirs disposed therein that are divided from one another. The first fluid reservoir holds a first mixture including a first aerosol propellant and a first part of a silicone based topical skin adhesive that is dissolved in the first aerosol propellant. The second fluid reservoir holds a second mixture including a second aerosol propellant and a second part of the silicone based topical skin adhesive that is dissolved in the second aerosol propellant. An aerosol spray dispensing system is connected with the container, which is configured to combine the first and second mixtures to form the silicone based topical skin adhesive and dispense the silicone based topical skin adhesive from the container as an aerosol spray.

The present invention provides a hemostatic porous composite sponge comprising i) a matrix of a biomaterial; and ii) one hydrophilic polymeric component comprising reactive groups wherein i) and ii) are associated with each other so that the reactivity of the polymeric component is retained, wherein associated means that said polymeric component is coated onto a surface of said matrix of a biomaterial, or said matrix is impregnated with said polymeric material, or both.

The present invention provides a hemostatic porous composite sponge comprising: i) a matrix of a biomaterial; and ii) one hydrophilic polymeric component comprising reactive groups wherein i) and ii) are associated with each other so that the reactivity of the polymeric component is retained, wherein associated means that said polymeric component is coated onto a surface of said matrix of a biomaterial, or said matrix is impregnated with said polymeric material, or both.

A system has a first fluid dispenser containing a biocompatible polymer, a second fluid dispenser containing a biocompatible curing agent selected to form a highly viscous mixture with the biocompatible polymer, a pair of diverging surfaces having a contact point, the first fluid dispenser and the second fluid dispenser positioned to dispense a first fluid and a second fluid at the contact point, and an actuator connected to the first fluid dispenser, the second fluid dispenser and the pair of diverging surfaces, the actuator configured to cause the first fluid dispenser and the second fluid dispenser to dispense the fluids at the contact point, and to cause the diverging surfaces to move through the contact point and then diverge, causing the mixture to form filaments until the filaments break up to form a spray. A method of forming a spray includes dispensing a biocompatible polymer solution and a curing agent onto a pair of diverging surfaces to form a mixture, moving the two diverging surfaces counter to each other to cause the mixture to form filaments between the two diverging surfaces as the diverging surfaces move away from each other, moving the two diverging surfaces further counter to each other to cause the filaments burst into droplets, and directing the droplets onto a surface. A composition of matter comprising a biocompatible polymer and a biocompatible curing agent.

An aerosol spray device includes a container having first and second fluid reservoirs disposed therein that are divided from one another. The first fluid reservoir holds a first mixture including a first aerosol propellant and a first part of a silicone based topical skin adhesive that is dissolved in the first aerosol propellant. The second fluid reservoir holds a second mixture including a second aerosol propellant and a second part of the silicone based topical skin adhesive that is dissolved in the second aerosol propellant. An aerosol spray dispensing system is connected with the container, which is configured to combine the first and second mixtures to form the silicone based topical skin adhesive and dispense the silicone based topical skin adhesive from the container as an aerosol spray.

A haemostatic composition comprising a non-acidic meshed network of fibrous material, wherein the network comprises fibres with a mean diameter (Dso) no greater than 1 μm, an aspect ratio (mean fibre length/mean fibre diameter) of at least 100, and wherein said meshed network has a specific surface area of at least 1O m.sup.2/g, and a gel point no greater than 3 g/L.

A protective film forming spray for skin surface includes a spray bottle filled with an undiluted spray solution and a propellant, the undiluted spray solution containing 2 to 40 mass % of water-soluble resin and 2 to 40 mass % of water-insoluble resin so that a total content of the water-soluble resin and the water-insoluble resin is 15 to 50 mass % and a remainder is solvent.

The invention features methods and devices for controlling bleeding from blood vessels that may be damaged as a result of trauma or impact with an object, such as a bullet or shrapnel. The device may be wearable by a user and include one or more components, such as wound sealant and multiple inflatable balloons/bladders. The device may be integrated into a garment, e.g., a vest, jacket, trousers, or full body suit. Once triggered (automatically or manually), the device may be used to deliver wound sealant to a wound site and/or pressure to the wound site by selective inflation of one or more balloons over exsanguinating blood vessels that may be damaged, thereby stopping or minimizing the bleeding. Alternatively, or in addition, the device may be used to stabilize a wounded wearer for, e.g., transportation purposes, or to provide buoyancy. Devices of the invention may also be used as a blood pressure monitor, as a massaging device, and as a breast pump. Devices and methods of the invention may also be used for repairing or stabilizing machines, such as vehicles (e.g., automobiles and boats).

A method of using a film-forming material for pre-treating an area of skin to reduce friction-related skin irritation, resulting in a reduced risk of acquiring skin chafing and/or blisters, such as may be caused by the wearing of shoes that abrade skin, and particularly including heels, said method comprising the steps of providing a dispensing device containing a film-forming material that includes a friction-reducing and/or friction-blocking element, and applying such film-forming material to an area of skin to reduce friction and thereby reduce the risk of acquiring chafing and/or a blister.

The present invention provides a hemostatic porous composite sponge comprising: i) a matrix of a biomaterial; and ii) one hydrophilic polymeric component comprising reactive groups wherein i) and ii) are associated with each other so that the reactivity of the polymeric component is retained, wherein associated means that said polymeric component is coated onto a surface of said matrix of a biomaterial, or said matrix is impregnated with said polymeric material, or both.