A surface is covered with microstructures that extend from the surface, and are made of a resilient material that allows the microstructures to bend or articulate. The microstructures are generally columnar and can have fingers on their distal or top end that is opposite the base from which the microstructures extend. In addition to the ordinary roughness presented by the microstructures, the articulation further discourages biofouling and bioadherence. The articulation of the microstructures can be oriented, and the orientations can be mixed or varied among the microstructures so that adjacent ones of the microstructures have different orientations of articulation.

An adhesive device used as a wound dressing, ingredient delivery device or IV hold-down in which inadvertent edge release of these devices along the periphery of the polymeric film layer is minimized when the handling layer, which is adhered to the polymeric film layer, is removed after application of the polymeric film layer to the patient.

Foam wound inserts with high-density and low-density regions, methods for making wound inserts, wound-treatment methods, and wound-treatment systems.

Foam wound inserts with high-density and low-density regions, methods for making wound inserts, wound-treatment methods, and wound-treatment systems.

Foam wound inserts with high-density and low-density regions, methods for making wound inserts, wound-treatment methods, and wound-treatment systems.

The subject disclosure is directed to antimicrobial bandages with nanostructures, formation thereof, and usage thereof to facilitate wound healing. In one embodiment, a bandage apparatus that facilitates healing a wound is provided. The bandage apparatus comprises a substrate comprising an attachment mechanism that facilitates removably attaching the substrate to a part of a body comprising the wound. The bandage apparatus further comprises a nanostructure film provided on a surface of the substrate and configured to contact the wound when the substrate is attached to the part of the body comprising the wound, wherein the nanostructure film comprises a plurality of nanostructures.

The present disclosure relates to a dermal drug delivery platform comprising: a primary wound dressing comprising three-dimensional polymer protuberances that extend upward from the dressing surface to engage the wound. The protuberances comprise at least one biocompatible and/or biodegradable polymer and medicinal nanoparticles. In one embodiment, the medicinal nanoparticles may be metallic and provide surface-area-enhanced galvanic action to drive medicinal ions into the wound bed. Various methods of making the disclosed dermal drug delivery platform, as well as three-dimensional methods of treating a wound using the platform are also disclosed.

Bandage apparatus, methods, and antimicrobial bandages for facilitating wound healing by providing an antimicrobial functionality. A bandage apparatus includes a substrate with a first surface and a second surface opposing the first surface. An attachment mechanism and a nanostructure film are provided on the first surface. The attachment mechanism facilitates removably attaching the substrate to a part of a body comprising a wound. The nanostructure film includes a plurality of nanostructures that contact the wound without puncturing the wound when the substrate is attached to the part of the body comprising the wound.

Foam wound inserts with high-density and low-density regions, methods for making wound inserts, wound-treatment methods, and wound-treatment systems.

An article comprising a macroporous wound-packing material and a microcorrugated microporous wound-contact layer is provided. The wound packing material is coupled to and/or substantially surrounded by the wound-contact layer. The average pore diameter of the microporous layer is less than or equal to about 90 m. A method of treating a wound using a microcorrugated microporous wound-contact layer and a macroporous wound packing material is also provided.