The present invention relates to a prosthetic fabric comprising an arrangement of yarns defining at least two faces for said fabric, said fabric comprising, on at least one of its faces, one or more barbs that protrude outwards relative to said face, characterized in that said barbs are covered with a coating made of a water-soluble biocompatible material. The invention also relates to a process for obtaining such a fabric and to prostheses obtained from such a fabric.

The present disclosure relates, in some aspects, to orthopaedic implants for securing soft tissue to bone and methods for using the same. One particular implant comprises a first exposed porous surface region, having pores for promoting bone ingrowth, and a second exposed porous surface, having pores for promoting soft tissue ingrowth. At least some of the pores of the first exposed porous surface region may be seeded with osteocytic factors and at least some of the pores of the second exposed porous surface region may be seeded with fibrocytic factors. Such orthopaedic implants can advantageously facilitate regeneration of the soft tissue to bone interface.

A stent includes an elongated tubular member formed from at least one filament, the elongated tubular member including a first segment in which the at least one filament is knitted into a first knitted pattern providing the first segment with a first performance characteristic and a second segment in which the at least one filament is knitted into a second knitted pattern providing the second segment with a second performance characteristic different from the first performance characteristic. Either the first knitted pattern or the second knitted pattern includes a plurality of anti-migration loops that extend radially outwardly from the elongated tubular member.

A method of reducing blood flow within an aneurysm includes: injecting a contrast agent into a blood vessel including an aneurysm; expanding a stent, from a delivery device, across the aneurysm; and confirming that a stagnated area forms in the aneurysm. The stagnated area can form a crescent shape, a mushroom shape, a hemispherical shape, and/or a flat side. Upon confirming that the stagnated area forms in the aneurysm, the delivery device can be withdrawn from the blood vessel. The stagnated area can include the contrast agent. If the stagnated area does not form in the aneurysm, a second occluding device may be deployed. After withdrawing the delivery device, substantially all of the aneurysm progressively thromboses.

A method and apparatus is provided for creating a modified tissue graft, wherein an anatomical site at which the modified tissue graft is to be placed is identified, desired characteristics for the modified tissue graft are identified based at least upon the anatomical site, one or more types of graft modifications and regions of the tissue graft to be modified are identified to achieve the desired characteristics; and at least a first area and a second area of the exterior surface of the tissue graft are modified by compressing, cutting and/or removing one or more portions thereof to create first designed surface features which cause the tissue graft to have first characteristics in the first area and second designed surface features which cause the tissue graft to have second characteristics in the second area.

A T-shaped anchorable mesh having a reticular structure with an intertwining mesh material, forming a tissue contact surface. The T-shaped anchorable mesh includes a long arm and a fixation part. The long arm has two lateral ends spaced from each other in an X direction and two marginal edges extending between the two lateral ends. The fixation part extends from one of the two marginal edges in a Y direction. The fixation part includes a plurality of protrusions emerging from the tissue contact surface.

Reversibly deformable corneal implants for replacing excised corneal tissue, the implants including an optical portion and an anchoring portion having different mechanical properties from each other.

An implantable vein frame is contemplated in which two ring members are rigidly joined in spaced axial alignment via one or more interconnecting members. One of the one or more interconnecting members defines a protruding region that acts upon the implant placed within the frame and/or the vein that the vein frame is placed within to define a sinus region. The implant is placed within and scaffolded by the vein frame, and the vein frame is subsequently inserted within a vein via a venotomy, or interposed between two vein segments via vein interposition graft. The vein frame acts to support the structural integrity of the implant, and to scaffold and anchor the implant in place with the vein.

A fluidic bridging tube (1), for bridging membranes in the human or animal body allowing the passage of fluid, has a proximal flange (2), an inter lumen connector (3) with a lumen (5) and a distal flange (4). The tube comprises a metal skeleton or scaffold structure (51) and a surrounding polymer which is softer than the scaffold structure. The scaffold structure (51) has a tubular mesh providing structural strength to the inter lumen connector. The tubular mesh has members (61) defining substantial rectangular mesh apertures, and distal crowns (64). At its proximal end the scaffold structure comprises spines (68) extending from a proximal tubular mesh rim (63). The spines provide structural strength to the proximal flange (2). In the preferred embodiment the tube is a tympanostomy tube. A method of manufacturing the tube comprises providing the scaffold structure and over-moulding the outer material to form the shape of the proximal flange, the inter lumen connector with a lumen, and the distal flange.

A tubular prosthesis that includes a scaffolding formed by at least one scaffolding filament; a cover; and at least one controlled ingrowth feature constructed and arranged to abut an inner surface of a lumen wall when the prosthesis is implanted in the body lumen. The controlled ingrowth feature may extend inwards or outwards from the prosthesis outer surface. The controlled ingrowth feature may be formed by a scaffolding filament; by a separate filament; by the cover; and combinations thereof.