A system for fracturing a frame of a deployed prosthesis with ultrasonic vibration includes a shaft, a tip assembly, an ultrasonic electric generator, and an ultrasonic transducer. The shaft includes a proximal portion and a distal portion. The tip assembly is coupled to the distal portion of the shaft. The tip assembly includes a cutting edge. The ultrasonic transducer is electrically coupled to the ultrasonic generator. Ultrasonic vibration generated by the ultrasonic transducer is translated to the tip assembly. The cutting edge of the tip assembly is configured to focus the vibration of the tip assembly onto a frame of a deployed prosthesis to fracture the frame of the prosthesis. The ultrasonic transducer may be coupled to the proximal portion or the distal portion of the shaft.

A medical treatment system for determining administration of medications to a patient is disclosed. The system uses a plurality of sensors to perform a first set of physiologic measurements in a right side of the heart and a second set of physiologic measurements in a left side of the heart. The system also includes a receiver configured to receive measurement data regarding the first and second sets of physiologic measurements and output to a display device the received measurement data.

A system for fracturing a frame of a deployed prosthesis with ultrasonic vibration includes a shaft, a tip assembly, an ultrasonic electric generator, and an ultrasonic transducer. The shaft includes a proximal portion and a distal portion. The tip assembly is coupled to the distal portion of the shaft. The tip assembly includes a cutting edge. The ultrasonic transducer is electrically coupled to the ultrasonic generator. Ultrasonic vibration generated by the ultrasonic transducer is translated to the tip assembly. The cutting edge of the tip assembly is configured to focus the vibration of the tip assembly onto a frame of a deployed prosthesis to fracture the frame of the prosthesis. The ultrasonic transducer may be coupled to the proximal portion or the distal portion of the shaft.

A body of the device to position a coronary stent or pull a catheter transducer for intravascular ultrasound is composed of a front and a rear portion each of which comprises two similar halves, a ring on the front smooth portion of the body and a brace over the rear portion of the rear portion of the body. The rear portion of the body overlaps the front portion of the body. The front portion of the body is truncated on one side thereof and continuously extends on the opposite side thereof in the form of a smooth cylindrical portion of a smaller diameter and a runner guide. A cylindrical slot with point elements is provided along the circumference of the cylindrical portion of the front portion of the body on the side of the runner guide. A cylindrical brace is mounted on the rear portion of the body.

The present invention is directed to a miniaturized biosensor and nanotechnology which is embedded in a variety of medical devices which can be used for real-time device location tracking and analysis, for the purpose of optimizing device positioning both at the time of initial placement and throughout its clinical use (i.e., device continuum). The continuously acquired device-specific standardized data is then transmitted through wireless communication networks to provide continuous feedback and alerts to authorized clinical providers as to device positioning, clinical performance, and presence of pathology.

The present invention relates to agent delivery systems for application to biological tissues. More specifically, the present invention relates to devices and methods for the non-invasive delivery of agents (e.g. pharmaceuticals and the like) into and across biological tissues using ultrasound and nanoporous carriers.

A method for operating an ultrasonic reentry device, includes: providing an ultrasound transmission member having a proximal end and a distal end; providing a catheter body having a lumen surrounding the ultrasound transmission member; providing a dilator slidably disposed within the lumen of the catheter body, the dilator surrounding the ultrasound transmission member; and exposing the distal end of the ultrasound transmission member from a distal end of the dilator.

Delivery devices and vascular devices are described for addressing a target site within a body lumen. The delivery device includes one or more ultrasound transducers positioned to transmit and receive ultrasound signals so as to provide an image of an interior of the patient's blood vessel within which the vascular device is disposed in real time, as the procedure is taking place. Using the images provided by the ultrasound transducers, the longitudinal and rotational position of the delivery device (and the vascular device constrained therein) may be adjusted to align the vascular device with the patient's vasculature. In some examples, the vascular device being delivered includes fenestrations, whereas in others the vascular device integral branch grafts.

A hand-held device for home use is disclosed for cleaning eyelids, eye margins and eye lashes. The device includes a housing, which forms a handle, and a cleaning head, attached on one end. In accordance with an important aspect of the invention, a vibration generator is used to drive the cleaning head sonically. The sonically driven cleaning head is placed in contact with one or both eye lids for each eye and either held in a stationary position or moved from side to side or back and forth. The vibration of the cleaning head in contact with the soap and effectively scrubs the upper eyelid or lower eyelid without the need for vigorous scrubbing or significant agility. The vibrating cleaning head is a more effective daily home cleaning tool for eyelids and eyelashes than known devices with rotary swabs or sponges.

A delivery system for percutaneously deploying a valve prosthesis. The system includes a catheter assembly including a delivery sheath capsule and a handle having an oscillating device. The capsule is configured to compressively retain the valve prosthesis during implantation. After the valve prosthesis is partially exposed during implantation, the oscillating device can create a vibratory motion to reduce the friction between the valve prosthesis and the delivery sheath capsule in order to recapture the valve prosthesis.