Provided herein are compositions and methods for treating bone fractures. In particular, provided herein are systems comprising carbon fiber sleeves and biocompatible polymers and the use of such systems in treating or preventing bone fractures.

A medical implant system is described for inhibiting infection associated with a joint prosthesis implant. An inventive system includes an implant body made of a biocompatible material which has a metal component disposed on an external surface of the implant body. A current is allowed to flow to the metal component, stimulating release of metal ions toxic to microbes, such as bacteria, protozoa, fungi, and viruses. One detailed system is completely surgically implantable in the patient such that no part of the system is external to the patient while the system is in use. In addition, externally controlled devices are provided which allow for modulation of implanted components.

A stent able to minimize occurrences of strain and stress concentration in a drug coat layer upon expansive deformation of the stent in a radial direction to avoid the possibility of the drug separating from the stent, includes a stent body and a drug coating layer coated on the outside surface of the stent body so that the thickness of the drug coating layer gradually decreases toward a bent portion of the stent.

Provided herein are compositions and methods for treating bone fractures. In particular, provided herein are systems comprising carbon fiber sleeves and biocompatible polymers and the use of such systems in treating or preventing bone fractures.

Implantable electrochemical sensors for the pH measurement are herein described, comprising a working electrode and a reference electrode, in which both the working electrode and the reference electrode are integral part of an implantable orthopaedic medical device, as well as a method for their preparation and their use for monitoring the progression of bacterial infections in the implant sites of such orthopaedic medical devices.

Methods and devices for correcting wear pattern defects in joints. The methods and devices described herein allow for the restoration of correcting abnormal biomechanical loading conditions in a joint brought on by wear pattern defects, and also can, in embodiments, permit correction of proper kinematic movement.

A biocompatible polymer hybrid nanocomposite coating on a surface of a substrate, such as titanium and its alloys. The coating can be achieved by an electrostatic spray coating, preferably using ultra-high molecular weight polyethylene (UHMWPE) as a matrix for the coating. For example, up to 2.95 wt. % carbon nanotubes can be used as reinforcement, as can up to 4.95 wt. % hydroxyapatite. A dispersion of CNTs and HA in the coating is substantially uniform. The tribological performance of such coatings include high hardness, improved scratch resistance, excellent wear resistance, and corrosion resistance compared to pure UHMWPE coatings.

A blood filter delivery system for delivering a filter into a vein from either a femoral or jugular access. The preferred system includes an introducer and a push-rod with a spline member disposed along the push-rod and a pusher member disposed on a distal end. The spline member has a main body, first and second boss portions spaced apart along the longitudinal axis to provide a gap for retaining anchor members of the filter during delivery via the introducer. In an alternative embodiment, a preferred filter includes first and second filter structures diverging in opposite directions. A link is connected to portions of each of the first and second filter structures so that each filter structure can be independently collapsed into a generally cylindrical shape.

Devices and methods for orthopedic support are disclosed. The device can have a first rigid section hingedly attached to a second rigid section. The device can be curved or rotated around obstructions along an access path to a target site. The device can be delivered to an intervertebral location in a patient.

Methods and devices for correcting wear pattern defects in joints. The methods and devices described herein allow for the restoration of correcting abnormal biomechanical loading conditions in a joint brought on by wear pattern defects, and also can, in embodiments, permit correction of proper kinematic movement.