Introduced here are containers designed to promote compliance with regimens for administering the medications stored therein. These containers can facilitate the conveyance of information related to a regimen through the use of a non-written medium. A container may include one or more display elements configured to emit/reflect light to indicate when medication stored in the container should be administered. An example of a display element is a light-emitting diode (LED). Emittance/reflectance of the light by the display element(s) may be governed by a different clock signal than the clock signal used to determine whether doses of medication are due to be administered.

Various embodiments relate to systems and methods for monitoring adherence to a medication regimen through the use of a smart medication container. The container can include an electronic display that presents relevant information, such as dosage and/or medication information, instructions, user information, messages, notifications, and device information (e.g., battery status, network connectivity status). A pair of conductive elements positioned on either side of the container's opening can be configured to continually measure capacitance in order to identify when contents (e.g., pills) leave the container. More than one pair of conductive elements may be used to improve accuracy and reduce the effects of noise. A processor is able to analyze the capacitance data and determine whether medication has been dispensed from the container and, if so, how much medication was dispensed. A computer system can then compare the results to a planned medication regimen to determine a state of compliance.

Method for generating user interface that indicates medication changes in medication starts with a processor detecting a medication change event. Processor retrieves medication information based on the medication change event including images of two medications. Processor generates color difference output using a color neural network, image of first medication and second medication. Color difference output comprises information on a difference in hue, saturation or color distribution. Processor generates medication appearance difference output using medication appearance neural network, image of first medication and second medication. Medication appearance difference output comprises information on a difference in shape, segmentation or form. Processor generates a differential record using the color difference output and medication appearance difference output. Processor causes medication change user interface to be displayed that comprises medication images and color and appearance descriptions of the medication which are displayed to emphasize differences identified in the differential record. Other embodiments are disclosed herein.

A portable medicament case that includes a medicament provided in a package, and first and second housing members that are configured to form a medicament package receiving cavity when joined together. Each housing member including a mating member that is configured for engagement with the other housing member in order to join the first and second housing members together in a sealed configuration that prevents moisture or contaminants from entering into the cavity. Also, a magazine containing a plurality of medicament cases for administration of medicaments to a group of people, and a method of administering medications to mass casualties of multiple persons that are in need thereof. The medicaments are rapidly disintegratable and can include a dye that stains the person's mouth so that medical personnel can determine who has been treated with the medicament.

Item-management systems, apparatus, and methods are described, preferably for management of items such as medicaments. In embodiments, an item-management system comprises a container defining plural cells, a docking station configured to receive the container, sources of visible information to indicate the cell(s) into which an item is to be loaded, and at least one controller operable to control the visible information sources to indicate the cell into which the item is to be received.

A medicine dispensing device, configured to contain a liquid medicine to be dispensed by the medicine dispensing device and having a plurality of dosing indicia spaced apart from each other around and in relation to a circumference of a surface of the medicine dispensing device, each dosing indicia being of a different height relative to a reference level and corresponding to different dose of the liquid medicine.

A fluid delivery manifold system assembled and configured to allow delivery of a single dose of a therapeutic agent (e.g., vaccine, drug, medicament, etc.) from a Blow-Fill-Seal (BFS) vial to a patient. The delivery assembly generally includes a modular manifold design consisting of separately constructed components cooperatively arranged and coupled to one another. The modular manifold construction allows for rapid manufacturing reconfigurations of one or more components with minimal costs to create new delivery manifold configurations that meet specific needs (i.e., different modes of delivery depending on agent to be delivered, such as subcutaneous, intramuscular, intradermal, intravenous injection, spray, or droplet delivery).

An injectable medication tab used to track expiration dates has an informative tab, a release string, an adhesive liner, and a quick release fastener. The informative tab provides visually accessible information about a bottle to which the injectable medication tab is attached. An expiration information portion of the informative tab protrudes from the exterior surface of the bottle after being opened. The adhesive liner is superimposed onto a mounting surface of the informative tab and attaches the informative tab to the bottle. The quick release fastener is a coupling mechanism that connects between an edge of the informative tab and the release string. The release string forms a detachable connection holding the expiration information portion against the bottle until the bottle is opened. Once opened, the expiration information section to protrudes from the bottle until the expiration information is recorded and the medical information portion is adhered to the bottle.

A system for sensing use of a pharmaceutical bottle may include a housing, a sensing plate mechanically coupled to the housing by a flexible expansion member, an activation plate mechanically coupled to the sensing plate, an electronic contact on the housing, an electrical circuit formed by the contact on the housing and the activation plate, an indicator configured to indicate use of the pharmaceutical bottle, a user interface configured to receive user input to control the indicator, and a processor and memory with instruction that when execute by the processor cause the system to determine that the pharmaceutical bottle has been used based on a change in the electrical circuit.

A system of prosthetic implants for a total knee replacement procedure is provided. The system includes a tibial component of a knee joint implant, a tibial insert configured to be positioned against the superior side of the platform of the tibial component, a first femoral component of a knee joint implant, and a second femoral component of a knee joint implant.