A61K2800/78

AGENT FOR MAINTAINING OR ENHANCING COLLAGEN PRODUCTION ABILITY

A novel an agent for maintaining or promoting collagen productivity is provided with.

An agent for maintaining or promoting collagen productivity of cells, comprising a wavelength conversion substance as an active ingredient; a composition and a product comprising the agent for maintaining or promoting collagen productivity; and a method for maintaining or promoting collagen productivity by means thereof are provided with. The present invention can exhibit a desirable effect on skin by effectively making use of ultraviolet light to maintain or promoting collagen productivity in skin cells.

BIOLOGICAL HAIR SHAPE CHANGE COMPOSITION AND KIT, AND METHOD FOR CHANGING HAIR SHAPE

A biological hair shape change composition including a macromolecular component, a small molecular component and an alkali agent component is provided. The macromolecular component includes a protease belonging to the class of alkaline proteases, and the small molecular component includes a peptide with reduction activity. Both the macromolecular component and the small molecular component are obtained from a fermentation product of Bacillus licheniformis and a keratin and/or keratin polymer-containing medium. Molecular weights of ingredients in the macromolecular component are greater than or equal to 3 kDa and are 3-1000 kDa, and molecular weights of ingredients in the small molecular component are less than 3 kDa and are 0.01-2.99 kDa.

Metschnikowia reukaufii extract and use in cosmetics

The invention relates to a cosmetic active ingredient comprising at least one Metschnikowia reukaufii extract, and the use of same for the cosmetic treatment of the skin, in particular for improving the radiance of the complexion by acting on the skin microbiota. The active ingredient is effective on mature skin. The invention also concerns compositions comprising the cosmetic active ingredient and a cosmetic method for treating the skin using these compositions.

Topical cosmetic compositions

A method of treating a person's skin is disclosed. The method can include topically applying to the skin a composition comprising jojoba oil and an oil extract of Opuntia ficus-indica tuna or Opuntia ficus-indica nopales, or a combination thereof, to treat the person's skin.

BARRIER GUARD TECHNOLOGY
20220387282 · 2022-12-08 · ·

The present invention relates generally to methods and compositions useful for improving skin barrier function and reducing skin redness. The compositions comprise cholesterol, ceramide II, and shea butter or cholesterol, ceramide II, shea butter, saccharide isomerate, hydroxyphenyl propamidobenzoic acid, and Phoenix dactylifera (date palm) seed extract.

Use of a <i>Nephelium lappaceum </i>extract for increasing the firmness of the skin and/or of the mucous membranes

The invention relates to the use of various extracts of the Nephelium lappaceum plant for increasing the firmness and/or elasticity of the skin and/or mucous membranes, by increasing type I and/or type V collagen and/or LOX-L, fibulin-5, emiline-1 and/or fibrillin-1 gene and/or protein expression, and/or by decreasing CYR61 expression, in the skin and mucous membranes. Another subject of the invention relates to the use of said extracts in a cosmetic composition comprising at least one cosmetically acceptable excipient. Another subject further relates to a cosmetic care method comprising the application of the extract according to the invention or of a cosmetic composition comprising it, for increasing the firmness and/or elasticity of the skin and/or mucous membranes, by increasing type I and/or type V collagen, fibrillin-1 and/or LOX-L, fibulin-5, emiline-1 and/or fibrillin-1 gene and/or protein expression, and/or by decreasing CYR61 expression, in the skin and mucous membranes. A final subject relates to an N. lappaceum extract for use thereof, alone or in a dermatological or pharmaceutical composition, in the prevention and/or treatment of pathological conditions involving a loss of collagen protein and/or gene expression and/or a pathological loss of firmness of the skin and/or mucus membranes, such as rosacea and telangiectasia.

Alkylamido Compounds and Uses Thereof
20220354809 · 2022-11-10 ·

Disclosed herein are compounds that may be specific to PPAR and/or EGF receptors, and methods of making and using same.

COMPOSITION COMPRISING MELATONIN OR ITS DERIVATIVES WITH COENZYME Q10 AND USE THEREOF AGAINST AGEING OF THE SKIN

The invention relates to a composition comprising melatonin, a metabolite or derivative thereof and coenzyme Q10 and to use thereof for the production of a pharmaceutical or cosmetic composition for the treatment of the skin, said composition potentiating the movement of both molecules into the mitochondrion and facilitating percutaneous absorption, in which both the melatonin and the CoQ10 can reach all of the strata of the skin.

COMPOSITION COMPRISING SKELETAL MUSCLE STEM CELL-DERIVED EXOSOME AS ACTIVE INGREDIENT FOR IMPROVING SKIN CONDITION

The present disclosure relates to a composition containing extracellular vesicles isolated from skeletal muscle-derived stem cells as active ingredients, which exhibits the effect of skin aging delay, wound healing, scar reduction and skin whitening, thereby improving skin condition. The present disclosure can not only utilize tissues wasted after surgical operation, thus allowing easy supply of raw materials, but also takes advantage of natural substances, thereby being free from the risk of side effects even upon long-term administration. The composition of the present disclosure promotes the secretion of collagen, reduces reactive oxygen species and promotes re-epithelialization at wound site while remarkably inhibiting melanocyte proliferation, tyrosinase activity and melanogenesis. Accordingly, it can facilitate effective recovery from skin tissue damage caused by oxidative stress, physical wound, intrinsic aging at cell or tissue levels, or hyperpigmentation.

Uses of the peptide of sequence His-D-Trp-Ala-Trp-d-Phe-Lys-NH2 for reducing or delaying the appearance of cell senescence and signs of skin aging

The present invention relates to the cosmetic use of a composition including, as the active agent, 0.1 to 1 μM of a synthetic peptide of sequence His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 or one of the salts thereof in a physiologically suitable medium, in order to reduce or delay the appearance of cell senescence and signs of skin aging. The present invention also relates to a method for cosmetic treatment which relates to these novel uses, including comprising the steps of applying the composition, topically, at least once per day, for a period of at least two days.