The present invention provides pharmaceutical and nutraceutical compositions comprising a cannabinoid, e.g., cannabidiol (CBD), and D-?-tocopherol polyethylene glycol 1000 succinate (TPGS); as well as such nutraceutical compositions which further comprise at least one additional active agent such as a biomass of a higher Basidiomycetes mushroom or a combination thereof, or an extract obtained therefrom.

The present invention relates to a method for producing a water-soluble extract of a spent mushroom bed after mushroom bed cultivation, the method including extracting a water-soluble extract by bringing a spent mushroom bed after mushroom bed cultivation into contact with pressurized water at a temperature of 32 to 64 C. under a pressure equal to or higher than the saturated vapor pressure, wherein the water-soluble extract is capable of inhibiting a biofilm formed by Candida albicans. This provides: a method for producing a water-soluble extract of a spent bed after mushroom cultivation that can produce a water-soluble extract capable of effectively inhibiting biofilms formed by Candida albicans; a biofilm inhibitor; a method for producing a biofilm inhibitor; and a biofilm inhibition method.

A composition for weight reduction and body fat reduction, its preparation method and application are disclosed, which relates to the technical field of health food. The composition includes the following components: 10-30 parts of concentrated milk protein, 10-30 parts of soybean isolated protein powder, 10-30 parts of concentrated whey protein powder, 5-15 parts of skim milk powder, 0.5-15 parts of collagen peptide, 0.1-3 parts of Agaricus bisporus extract, 0.1-3 parts of Flammulina velutipes extract, 0.1-5 parts of okra powder, 0.1-2 parts of Opuntia ficus-indica extract, 1-10 parts of medium chain triglyceride microcapsule powder, 0.1-5 parts of mango concentrated powder, 0.1-2 parts of ginger oil microcapsule powder, 0.1-2 parts of citrus powder, 0.1-5 parts of guarana extract and 0.5-2 parts of compound vitamin.

A composition for the management of Human Papillomavirus (HPV) infections is provided. The composition comprises a combination of activated folate, one or more zinc compounds such as zinc sulfate, a phenol catechin such as Epigallocatechin-3-gallate (EGCG), broccoli seed or sprout, and one or more carotenoids. The composition may comprise one or more mushrooms or mushroom extracts. The composition may be useful for the control of symptoms associated with HPV infection in one or more individuals, and may also include reducing the frequency and/or persistence of HPV related conditions.

A composition for upregulating the immune system, endocannabinoid system and main bodily systems while promoting mental stability for optimal wellness. Also provided is a method for enhancing/stimulating the immune, endocannabinoid and/or main bodily systems of a patient, particularly a mammal with a disease or disorder, which includes a step of administering the composition to the patient. The composition includes a combination of Mushroom Spore Oil and/or Spore Powder and at and at least one of b1) a cannabinoid, b2) DMSO/Dimethyl Sulfoxide, b3) minerals, b4) botanicals, b5) Vitamins, b6) Amino Acids, and b7) fungi.

Provided is a method for preventing, improving or treating Alzheimer's disease, dementia or brain function degeneration in a subject in need, including administering to the subject a composition comprising purified mushroom -glucan, wherein the purified -glucan is derived from mushroom mycelium or its fermentation product, wherein the purity of the purified mushroom -glucan is 60% or above.

A composition for weight reduction and body fat reduction, its preparation method and application are disclosed, which relates to the technical field of health food. The composition includes the following components: 10-30 parts of concentrated milk protein, 10-30 parts of soybean isolated protein powder, 10-30 parts of concentrated whey protein powder, 5-15 parts of skim milk powder, 0.5-15 parts of collagen peptide, 0.1-3 parts of Agaricus bisporus extract, 0.1-3 parts of Flammulina velutipes extract, 0.1-5 parts of okra powder, 0.1-2 parts of Opuntia ficus-indica extract, 1-10 parts of medium chain triglyceride microcapsule powder, 0.1-5 parts of mango concentrated powder, 0.1-2 parts of ginger oil microcapsule powder, 0.1-2 parts of citrus powder, 0.1-5 parts of guarana extract and 0.5-2 parts of compound vitamin.

The present invention relates to a 100% natural product consisting of natural matrices showing emerging properties, which allows to re-establish a correct bone metabolism by correcting the behavior of mesenchymal stem cells and re-establishing the correct balance between the cell populations that allow bone growth or remodeling. The product of the invention, as demonstrated by the inventors, is itself a natural matrix, representing native natural intelligence, said natural intelligence being the only capable to allow a physiological endogenous interconnection with other entities which are self-assembled in nature, such as the human species. By reconstituting the correct functioning of bone metabolism, the product achieves beneficial results on a systemic scale ameliorating systemic metabolism and inflammatory status. Factually, the invention allows for a shift of paradigm based on the passage from a deterministic validation of properties to a probabilistic one based on functional redundancy logics, that will grant an industrially viable source of innovation for manufacturers in the field of 100% natural therapeutic or beneficial products.

The present invention relates to a 100% natural product consisting of natural matrices showing emerging properties, which allows to re-establish a correct bone metabolism by correcting the behavior of mesenchymal stem cells and re-establishing the correct balance between the cell populations that allow bone growth or remodeling. The product of the invention, as demonstrated by the inventors, is itself a natural matrix, representing native natural intelligence, said natural intelligence being the only capable to allow a physiological endogenous interconnection with other entities which are self-assembled in nature, such as the human species. By reconstituting the correct functioning of bone metabolism, the product achieves beneficial results on a systemic scale ameliorating systemic metabolism and inflammatory status. Factually, the invention allows for a shift of paradigm based on the passage from a deterministic validation of properties to a probabilistic one based on functional redundancy logics, that will grant an industrially viable source of innovation for manufacturers in the field of 100% natural therapeutic or beneficial products.

A composition useful for treating immune-mediated inflammatory diseases or cancer in mammalian subjects is disclosed. The composition comprises a synergistic combination of a cannabis derived compound, and a medicinal mushroom.