A61K47/6951

FORMULATION, COMPOSITION OR FOODSTUFF ADDITIVES FOR THE MODIFICATION OF GLYCEMIC RESPONSE METHODS OF MANUFACTURING AND USING THE SAME
20230049572 · 2023-02-16 · ·

The present disclosure relates generally to formulations, compositions or foodstuff additives for use in modulating a glycemic response for treating or preventing diabetes or obesity and processes and method of its manufacture. Described is a formulation, a composition or a foodstuff for modulating a glycemic response manufactured from at least one phenylpropanoid encapsulated in a first cyclodextrin; and a second cyclodextrin. Preferably, the at least one phenylpropanoid is quercetin, phlorizin, myricetin, dihydromyricetin or any combination thereof, the first cyclodextrin is gamma cyclodextrin, and the second cyclodextrin is alpha cyclodextrin.

Traditional Chinese medicine composition and preparation method and application thereof

A traditional Chinese medicine composition, made from cassia twig, poria, Cortex moutan, Radix paeoniae alba, peach kernel in equal proportions. The traditional Chinese medicine composition comprises paeoniflorin, amygdalin, benzoylpaeoniflorin, cinnamic acid, paeonol, and cinnamaldehyde. The composition has the advantages of high production efficiency, high content of effective ingredients, high transfer rate of poria acid, reduced hygroscopicity, and improved dissolution of index ingredients.

COMPOSITIONS OF JASMONATE COMPOUNDS AND METHODS OF USE
20180000958 · 2018-01-04 ·

The disclosure describes nanocarried and/or microcarried jasmonate compounds and their pharmaceutical compositions, as well as use thereof for treating or preventing angiogenesis-related or NF-κB-related disorders. Also disclosed are methods of making the nanocarried and/or microcarried compounds and their compositions.

SILYBIN INJECTION AND PREPARATION METHOD THEREFOR

A silybin injection contains silybin, sulfobutyl ether-β-cyclodextrin, an organic solvent for injection and may further contain a co-solvent, a lyophilization proppant, a pH regulator, water for injection and the like.

POLYMERIC DRUG CONJUGATES WITH TETHER GROUPS FOR CONTROLLED DRUG DELIVERY

Described herein is a cyclodextrin containing polymer conjugate.

PHARMACEUTICAL PREPARATION COMPRISING BREXPIPRAZOLE AND SUBSTITUTED BETA-CYCLODEXTRIN

Provided is an aqueous pharmaceutical preparation comprising 7-[4-(4-benzo[b]thiophen-4-yl-piperazin-1-yl)butoxy]-1H-quinolin-2-one (compound (I)) or a salt thereof, which shows improved water solubility of compound (I) or a salt thereof achieved by addition of substituted β-cyclodextrin. The present invention provides a pharmaceutical preparation comprising compound (I) or a salt thereof, and substituted β-cyclodextrin.

Cyclodextrin Compositions Encapsulating a Selective ATP Inhibitor and Uses Thereof

The invention provides compositions comprising cyclodextrins encapsulating a selective ATP inhibitor, as well as uses thereof.

MODIFIED CYCLODEXTRIN COATED MAGNETITE NANOPARTICLES FOR TARGETED DELIVERY OF HYDROPHOBIC DRUGS

The invention discloses a composition comprising surface modified iron oxide nanoparticles with citric acid modified cyclodextrin with a hydrodynamic diameter of less than 10 nm and a hydrophobic molecule.

The composition finds use in targeted delivery of a hydrophobic drug and as contrast agent in imaging applications.

Compositions and Methods for Treating NLRP3 Inflammasome-Related Diseases and Disorders
20180008629 · 2018-01-11 ·

The present invention provides compositions and methods for treating or preventing an NLRP3 immunosome-related disorder. In one embodiment, the method includes administering a therapeutically effective amount of a composition comprising at least one NLRP3 inflammasome inhibitor to a subject in need thereof.

TAXIFOLIN FORMULATION COMPRISING THIAMINE

The present invention relates to formulations of taxifolin with thiamine as a dosage form for oral administration, in particular as dietary supplements or foods for special medical purposes/FSMPs.