A laminate sheet includes a water-vapor permeable polyurethane film having a hard segment phase and a first spunbond nonwoven fabric disposed at one side in a thickness direction of the water-vapor permeable polyurethane film. The first spunbond nonwoven fabric contains stretchable fibers containing a thermoplastic polyurethane and non-stretchable fibers containing a polyolefin. The melting point of the hard segment phase is 65□ or more and 140□ or less.

A laminate patchable to a living body and that includes a pressure-sensitive adhesive layer for patching to the living body, a substrate layer disposed on a one-side surface in a thickness direction of the pressure-sensitive adhesive layer and supporting the pressure-sensitive adhesive layer, and a protecting layer disposed on a one-side surface in the thickness direction of the substrate layer.

A laminate patchable to a living body and that includes a pressure-sensitive adhesive layer for patching to the living body, a substrate layer disposed on a one-side surface in a thickness direction of the pressure-sensitive adhesive layer and supporting the pressure-sensitive adhesive layer, and a protecting layer disposed on a one-side surface in the thickness direction of the substrate layer.

Disclosed herein is a composite material comprising a substrate coated with a block copolymer brush, where the block copolymer brush comprises a first block of a hydrophobic polymer conjugated to a nitric oxide source, where the first block of the hydrophobic polymer is covalently bonded to a surface of the substrate or a first block of a cationic polymer covalently bonded to a surface of the substrate and a second block of a hydrophilic polymer, extending from the first block to form an outer surface of the block copolymer brush.

Disclosed herein is a composite material comprising a substrate coated with a block copolymer brush, where the block copolymer brush comprises a first block of a hydrophobic polymer conjugated to a nitric oxide source, where the first block of the hydrophobic polymer is covalently bonded to a surface of the substrate or a first block of a cationic polymer covalently bonded to a surface of the substrate and a second block of a hydrophilic polymer, extending from the first block to form an outer surface of the block copolymer brush.

Disclosed herein is a composite material comprising a substrate coated with a block copolymer brush, where the block copolymer brush comprises a first block of a hydrophobic polymer conjugated to a nitric oxide source, where the first block of the hydrophobic polymer is covalently bonded to a surface of the substrate or a first block of a cationic polymer covalently bonded to a surface of the substrate and a second block of a hydrophilic polymer, extending from the first block to form an outer surface of the block copolymer brush.

The present invention relates to large scale manufacture of nanoscale microsheets for use in applications such as wound healing or modification of a biological or medical surface.

The present invention relates to large scale manufacture of nanoscale microsheets for use in applications such as wound healing or modification of a biological or medical surface.

Adhesive hot-melt formulations with a main polymeric component, of at least one isotactic metallocene butene-1 polymer composition, that has a low viscosity, and that has a bimodal composition, directly obtained during polymerization, in two consecutive and separate reaction steps. Moreover, said hot-melts include less than 5% by weight of at least one viscosity modifier that is not solid at room temperature. Such unusually low level of said additives, surprisingly allows to attain substantially improved levels both of high adhesiveness and cohesion. The adhesive hot-melt formulations include less than 5% by weight of a polyethylene wax or of a blend of polyethylene waxes, that characterized by a highly linear/non-branched structure and by an exceptionally low Polydispersity Index. The presence of such peculiar polyethylene waxes, that are partially incompatible with the butene-1 polymer composition, allows to use the disclosed hot-melt formulations even in the presence of fibrous or perforated substrates.

Adhesive hot-melt formulations with a main polymeric component, of at least one isotactic metallocene butene-1 polymer composition, that has a low viscosity, and that has a bimodal composition, directly obtained during polymerization, in two consecutive and separate reaction steps. Moreover, said hot-melts include less than 5% by weight of at least one viscosity modifier that is not solid at room temperature. Such unusually low level of said additives, surprisingly allows to attain substantially improved levels both of high adhesiveness and cohesion. The adhesive hot-melt formulations include less than 5% by weight of a polyethylene wax or of a blend of polyethylene waxes, that characterized by a highly linear/non-branched structure and by an exceptionally low Polydispersity Index. The presence of such peculiar polyethylene waxes, that are partially incompatible with the butene-1 polymer composition, allows to use the disclosed hot-melt formulations even in the presence of fibrous or perforated substrates.