Dialysis machines comprising a feed arrangement to supply a dialysis fluid to a dialyzer during dialysis treatment and a return arrangement to remove the dialysis fluid from the dialyzer during dialysis treatment and forward it to an exit; a feed recirculation circuit to allow a fluid of the feed arrangement to be re-circulated in a fluid loop path comprising, at least a portion of, the feed arrangement and the feed recirculation circuit and a return recirculation circuit to allow a fluid of the return arrangement to re-circulate in an auxiliary fluid loop path comprising, at least a portion of, the return arrangement and the return recirculation circuit. A controller configured to perform disinfection by re-circulating a disinfectant and/or a heated fluid through said fluid loop path and/or through said auxiliary fluid loop path. The dialysis machine further comprises a feed forward arrangement connected to the fluid loop path and arranged to enable a fluid of the feed arrangement to be forwarded to the exit by-passing the auxiliary fluid loop path.

A blood purification apparatus that is capable of, with no preparatory operations, performing substitution by supplying dialysate in a dialysate introduction line to a blood circuit during ultrafiltration treatment, or performing blood return by immediately supplying the dialysate in the dialysate introduction line to the blood circuit after the ultrafiltration treatment. A blood purification apparatus includes a dialyzer, a dialysate introduction line, a dialysate drain line L2 through which drain liquid from the dialyzer is drained, and an ultrafiltration pump capable of removing water from the blood in the blood circuit. The blood purification apparatus is capable of performing substitution or blood return by supplying the dialysate in the dialysate introduction line L1 to the blood circuit. In an ultrafiltration treatment in which the ultrafiltration pump is activated while the introduction of the dialysate into the dialyzer is stopped, dialysate delivery is performed while the introduction of the dialysate into the dialyzer is prevented.

The invention relates to an extracorporeal blood treatment device comprising a hydraulic system II comprising a plurality of flow paths, the blood treatment device having a control unit 40 which provides an operating mode for disinfecting the hydraulic system with a liquid which can be supplied via one of the flow paths. Moreover, the invention relates to a method for operating an extracorporeal blood treatment device with a hydraulic system comprising a plurality of flow paths. The blood treatment device according to the invention is characterized in that the hydraulic system II has a valve device 23 which provides several switching positions. The valve device 23 has an inlet 25A for the liquid for disinfecting the hydraulic system and a plurality of outlets 26A, 27A, 28A, wherein in a switching position the inlet 25A is connected to one of the outlets 26A, 27A, 28A and in another switching position the inlet is connected to a plurality of outlets 26A, 27A, 28A. The inlet 25A of the valve device 23 is in fluid communication with the flow path via which liquid for disinfecting the hydraulic system II can be supplied, and the outlets 26A, 27A, 28A of the valve device 23 are in fluid communication with another flow path of the hydraulic system, so that liquid can simultaneously be supplied to the individual flow paths.

Systems and methods for managing the pH of a dialysate fluid during hemodialysis therapy. The systems and methods adjust dialysate pH and buffer concentration to generate a predetermined total bicarbonate buffer concentration in a dialysate entering a dialyzer.

An extracorporeal blood treatment device is provided that includes a hydraulic system having a plurality of flow paths. A control unit provides an operating mode for disinfecting the hydraulic system with a liquid supplied via one of the flow paths. A method for operating the extracorporeal blood treatment device is also provided. The hydraulic system has a valve device that provides several switching positions. The valve device has an inlet for a liquid for disinfecting the hydraulic system, and a plurality of outlets. In a first switching position, the inlet is connected to one of the outlets. In another switching position, the inlet is connected to a plurality of the outlets. The inlet of the valve device is in fluid communication with a first flow path and the outlets are in fluid communication with another flow path. Disinfecting liquid can simultaneously be supplied to the individual flow paths.

An extracorporeal blood treatment apparatus comprises: a blood treatment device (2) comprising a blood chamber (3) and a fluid chamber (4) separated from one another by a semipermeable membrane (5); an extracorporeal blood circuit (17) comprising a blood withdrawal line (6) connected to an inlet port (3a) of the blood chamber (3) and a blood return line (7) connected to an outlet port (3b) of the blood chamber (3); a blood pump (21) configured to be coupled to the blood withdrawal line (6); a hydraulic circuit (100) connectable to the fluid chamber (4), wherein the hydraulic circuit (100) comprises a fluid preparation device (9) connected to a water network (14) and configured to dilute concentrates in water to prepare a treatment fluid; a control unit (12) connected to the preparation device (9) and to the blood pump (21). The control unit (12) is configured to execute the following procedure: setting the hydraulic circuit (100) so that the fluid preparation device (9) bypasses the fluid chamber (4); controlling the fluid preparation device (9) to prepare the treatment fluid while bypassing the fluid chamber (4); and simultaneously controlling the blood pump (21) to perform pure ultrafiltration of a patient (P) connected to the extracorporeal blood circuit (17).

This disclosure relates to dialysis systems and methods. In some implementations, a dialysis system includes a dialysis machine with a fluid line and a drain line, a blood line set configured to be connected to the dialysis machine, and a drain apparatus coupled to the dialysis machine. The drain apparatus includes a chamber configured to receive an end of a patient line of the blood line set, an inlet line, an outlet line, and a valve. The inlet line has a first end configured to be coupled to the chamber and a second end configured to be coupled to the fluid line of the dialysis machine. The outlet line has a first end configured to be coupled to the chamber and a second end configured to be coupled to the drain line of the dialysis machine. The valve is configured to control flow of fluid through the outlet line.

Systems and methods for managing the pH of a dialysate fluid during hemodialysis therapy. The systems and methods adjust dialysate pH and buffer concentration to generate a predetermined total bicarbonate buffer concentration in a dialysate entering a dialyzer.

A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient to the dialyzer and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. In addition, the hemodialysis system includes two reservoirs which can be alternately placed in the dialysis flow path using various controllable fluid valves. The weight, and therefore the level of dialysate, of each reservoir is measured by a preferred level sensor having a strain measuring device which includes a load cell and a tilt sensor. The load cell and tilt sensor are electrically connected to a processor for sending force and tilt measurements to the processor. The processor may analyze the tilt measurements to correct for any inaccurate measurements of the load cell caused by the tilt.

The invention relates to an extracorporeal blood treatment apparatus comprising a blood treatment unit 1 that is divided by a semipermeable membrane 2 into a first compartment 3, which is part of a fluid system II, and a second compartment 4, which is part of an extracorporeal blood circuit I. The invention also relates to a method for operating a blood treatment apparatus of this kind. The blood treatment apparatus according to the invention has a pressure-based checking device 32 which interacts with the control unit 31 for a valve device 21 and is designed such that a fluid connection between an upstream portion 20A and a downstream portion 20B of a flow path 20 for a special operating mode can only be established if the pressure-based checking device 32 detects an operating state in which it is ensured that fluid in the flow path 20 for a special operating mode flows towards a flow path 10 leading to a drain 11. This ensures that the fluid in question can only flow into the flow path 10 that leads to the drain 11, and cannot get into another flow path 8 in which fresh treatment fluid is located.