A unit dose container for the containment of an intranasal formulation for use with the POD device.

Device for dispensing a fluid product comprising a body (1) having a dispensing opening (12) and a piercing element (4), said body (1) containing a reservoir (10) containing at least two doses of fluid product, said reservoir (10) having a proximal axial opening closed by a membrane (30) and a distal axial opening closed by a piston (20), mounted in a sliding manner in said reservoir (10) in order to dispense a dose of fluid product on each actuation, said reservoir (10) being axially movable with respect to said body (1) between a rest position, in which said piercing element (4) does not pass through said membrane (30), and a dispensing position, in which said piercing element (4) passes through said membrane (30), said membrane (30) being capable of reclosing in a sealed manner after each actuation, when said piercing element (4) comes back out from said reservoir (10), said device comprising a lateral actuation system having an actuating member (50), laterally movable with respect to said body (1) between a rest position and an actuating position, said actuating member (50) being resiliently biased towards the rest position thereof, said actuating member (50) comprising a first cam (51) cooperating with said reservoir (10) and a second cam (52) cooperating with said piston (20), such that the movement of said actuating member (50) to the actuating position thereof first moves said reservoir (10) to the dispensing position thereof then causes said piston (20) to slide in said reservoir (10), to dispense a dose of fluid product.

The present invention provides a method for estimating an amount of a powder shaped material passing a bend in a flow channel, such as how much drug from an inhaler reaches the lungs of a person. The estimation is based on both the flow rate of the inhalation as well as the rate of release of the drug into the flow channel, where the rate or release itself depends on the flow.

According to some embodiments there is provided a device configured for releasing at least one substance from source material, comprising: a housing; a plurality of source material sections positioned at fixed locations with respect to the housing; a plurality of airflow paths, each airflow path associated with at least one source material section; each airflow path associated with at least one blocking element which prevents flow of air through the path; and an actuator operably coupled to the blocking element, the actuator configured for unblocking the airflow path of at least one selected source material section to allow flow of air to and through source material within the selected section.

According to some embodiments there is provided a device configured for releasing at least one substance from source material, comprising: a housing; a plurality of source material sections positioned at fixed locations with respect to the housing; a plurality of airflow paths, each airflow path associated with at least one source material section; each airflow path associated with at least one blocking element which prevents flow of air through the path; and an actuator operably coupled to the blocking element, the actuator configured for unblocking the airflow path of at least one selected source material section to allow flow of air to and through source material within the selected section.

A non-nicotine pod assembly includes a non-nicotine reservoir to hold non-nicotine pre-vapor formulation, and a heater configured to vaporize non-nicotine pre-vapor formulation drawn from the non-nicotine reservoir. A device body is configured to engage with the non-nicotine pod assembly, and includes a controller. The controller is configured to cause the device body to detect a fault event at the non-nicotine electronic vaping device, classify the fault event as one of a plurality of types of fault events, and perform at least one consequent action based on the classification of the fault event.

Self-puncturing liquid drug cartridges and an associated inhaler are used to deliver one or more separate doses of an aerosolized liquid drug. A cartridge includes a needle assembly coupled to a drug container. The needle assembly includes a hollow needle and is reconfigurable from a first configuration to a second configuration upon insertion of the cartridge into the inhaler. In the first configuration, the hollow needle does not extend into the container. In the second configuration, the hollow needle extends into the container. The inhaler includes an aerosol generator that includes a vibratable membrane that aerosolizes liquid drug ejected from the cartridge for inhalation by a patient.

A thermally modulating inhalable medicament delivery device may deliver an inhalable medicament as an aerosol, vapor, or partial aerosol and partial vapor mixture. The inhalable medicament may be delivered to a target in a subject. Described herein are devices, systems, and methods for delivering an inhalable medicament to a subject.

A thermally modulating inhalable medicament delivery device may deliver an inhalable medicament as an aerosol, vapor, or partial aerosol and partial vapor mixture. The inhalable medicament may be delivered to a target in a subject. Described herein are devices, systems, and methods for delivering an inhalable medicament to a subject.

There is provided an aerosol-generating system including an aerosol-generating device in cooperation with an aerosol-generating article. The aerosol-generating article includes a first compartment including a volatile liquid; and a second compartment including a delivery enhancing compound. The aerosol-generating device includes an outer housing configured to receive the aerosol-generating article; a power supply; a heater, configured to receive power from the power supply and arranged to heat the first compartment when the aerosol-generating article is received in the outer housing; an input, configured to receive an input from a user; and a controller, configured to control an amount of power supplied to the heater in dependence on a user input, such that a quantity of volatile liquid aerosolised is determined by the user input.