To prevent accidental needle stick injuries, a syringe has a plunger configured to pull the syringe into the syringe barrel after clinical use. The syringe has an additional safety feature that restricts subsequent movement of the plunger. After the needle has been retracted in its entirety within the barrel of the syringe, movement of the plunger is restricted by a two-part locking mechanism, a notch on the plunger and a T-shaped slot on the barrel with a one-way catch section to prevent the needle tip from being pushed accidentally through the barrel wall.

One embodiment is directed to a method for safe injection, comprising: providing an injection assembly and inserting a plunger tip of the injection assembly to a final insertion state and releasing an associated manual insertion load. A retraction load developed sufficient to cause the plunger tip to be proximally withdrawn pulls the retractable needle proximally relative to the needle housing to a retracted state wherein a distal tip of the needle becomes mechanically locked into an encapsulated configuration wherein it is no longer exposed for injection.

A drug delivery device (1) comprising a delivery unit (2) receiving a drug cartridge (3) containing a drug to be administered to a patient in need thereof, the delivery unit comprising a subcutaneous delivery mechanism (7) including a needle (24), a needle support (8) to which the needle is mounted, and a needle actuation mechanism (9) configured to move the needle from a retracted position within a housing (5) of the delivery unit (2), to an extended delivery position where the needle projects through a base wall (14) of the housing. The needle actuation mechanism comprises a rotary actuator (10) configured to engage an engagement lever (11) coupled to the needle support (8) for translating the needle support between retracted and extended delivery positions.

A syringe provided with a body, a piston capable of sliding in the body, and an injection device comprising a needle oriented along a longitudinal axis and a casing removably secured to the body and carrying said needle. The casing comprising a plurality of flexible tabs, each provided with a stop. The piston comprising a docking system having a housing comprising a flange configured to hold the stops of the flexible tabs in the housing in an insertion position in which the tabs are inserted into the housing, the plurality of tabs in opposing areas around the longitudinal axis. The flange comprising bearing areas configured to be in contact with corresponding tabs in the insertion position. The tabs are configured to exert an elastic pressure on corresponding bearing areas in the insertion position, and the bearing areas are dissymmetrical relative to the longitudinal axis.

A drug delivery device (1) comprising a delivery unit (2) receiving a drug cartridge (3) containing a drug to be administered to a patient in need thereof, the delivery unit comprising a subcutaneous delivery mechanism (7) including a needle (24), a needle support (8) to which the needle is mounted, and a needle actuation mechanism (9) configured to move the needle from a retracted position within a housing (5) of the delivery unit (2), to an extended delivery position where the needle projects through a base wall (14) of the housing. The needle actuation mechanism comprises a rotary actuator (10) configured to engage an engagement lever (11) coupled to the needle support (8) for translating the needle support between retracted and extended delivery positions.

A syringe is provided with a body, a piston capable of sliding in the body, and an injection device comprising a needle oriented along a longitudinal axis and a casing removably secured to the body and carrying said needle, the casing comprising a plurality of flexible tabs each provided with a stop, the piston comprising a docking system provided with a housing that comprises a flange configured to hold the stops of the flexible tabs in the housing in an insertion position in which the tabs are inserted into the housing, the plurality of tabs comprising a first tab and a second tab situated in opposing areas around the longitudinal axis, the flange comprising a first bearing area and a second bearing area configured to be in contact respectively with the first tab and the second tab in the insertion position.

One embodiment is directed to a safety syringe system, comprising: an off-the-shelf syringe assembly comprising a syringe body and a plunger tip; a needle assembly removably coupleable to the distal end of the syringe body such that medicinal fluid may be transferred through a retractable needle coupled to a needle housing comprising the needle assembly upon insertion of the plunger tip relative to the syringe body; and a plunger control assembly coupled to the plunger tip and configured to facilitate manual insertion of the plunger tip relative to the syringe body; wherein upon insertion of the plunger tip to a final insertion state and release of an associated manual insertion load, the plunger tip may be proximally withdrawn, pulling the retractable needle proximally relative to the needle housing to a safe locked and retracted state wherein it is no longer exposed for injection.

A package comprising a container for holding a first sub-stance, and a product insert for holding a second substance, at least partially inserted info said container, and where the first product and the second product can be allowed to merge by external manipulation of said package. Packaged products and methods are also provided.

The invention relates to a syringe with a retractable needle comprising a barrel (2) having a nozzle (19) integrated in a male Luer adapter element (26); a piston (3) slidably arranged in the barrel (2) and coupled to a sealing element (16), said sealing element (16) having a central channel (20); a needle assembly comprising a needle (4), a needle holder (6) and a female Luer adapter element (7); a spring assembly arranged in the piston (3) comprising a spring sleeve (12), a spring (13) mounted on the spring sleeve (12), a spring tensioning element (14) located on the spring sleeve (12) and held in position by the piston wall, and a plunger (15) mounted within the spring sleeve; and a piston cap (10); said piston (3) being coupled to the sealing element (16) by means of the spring tensioning element (14); said spring sleeve (12) being held in position within the piston (3) by a ring element (18) protruding from the inner wall of the piston (3) and supporting the proximal end of the spring sleeve (12), the spring sleeve extending into the channel (20) of the sealing element (16) to the distal end thereof; said spring sleeve (12) comprising at its distal end a circular protrusion (21) on the inside designed to engage a circular recess (22) at the proximal end of the needle holder (6); wherein the piston (3) comprises a holding ring (11) on its inner surface designed to engage with an outer flange (17) of the spring sleeve (12) after actuation of the spring (13).

A drug delivery device (1) comprising a delivery unit (2) receiving a drug cartridge (3) containing a drug to be administered to a patient in need thereof, the delivery unit comprising a subcutaneous delivery mechanism (7) including a needle (24), a needle support (8) to which the needle is mounted, and a needle actuation mechanism (9) configured to move the needle from a retracted position within a housing (5) of the delivery unit (2), to an extended delivery position where the needle projects through a base wall (14) of the housing. The needle actuation mechanism comprises a rotary actuator (10) configured to engage an engagement lever (11) coupled to the needle support (8) for translating the needle support between retracted and extended delivery positions.