The disclosure relates to systems, methods and apparatus of storing, transporting, mixing, and injecting a drug as a solution, and in some embodiments, to a drug injection apparatus and system intended for use in mixing on demand a drug with a liquid, such as water, in a premeasured quantity and dosage, and injecting the drug mixture using an integrated hypodermic needle assembly. Also provided are methods of using such apparatus and systems.

The invention relates to a pre-filled injection device with a non-removable cartridge embedded in the housing structure and wherein the piston rod drive mechanism comprises a threaded piston rod which is moved helically in a nut secured to the housing structure. During assembly of the injection device it is possible to eliminate the air-gap between the plunger in the cartridge and the piston rod means by moving the nut element for the drive mechanism axially during assembly. In an alternative solution, the piston rod comprises a telescopic element which can slide axially in relation to the piston rod to obtain the zero position.

A drug delivery device configured to provide a dose of medicament is disclosed. The drug delivery device includes a main housing, a syringe arranged in the main housing, and a pneumatic power pack arranged in the main housing. The pneumatic power pack includes a pressurized gas source storing pressurized gas, a valve for the pressurized gas source, a sleeve having an inner wall, and a plunger. The sleeve is configured to receive pressurized gas released from the pressurized gas source. The plunger is in sliding gas-tight engagement with the inner wall of the sleeve. Upon activation of the valve, the valve releases the pressurized gas, and the released pressurized gas flows into the sleeve and propels the plunger in a distal direction with respect to the sleeve and the syringe, so as to eject medicament from the syringe.

A drug delivery device is disclosed, wherein the device comprises a housing; a product container arranged in the housing; a plunger rod partially disposed inside the product container; and a thumb pad configured to receive a portion of the plunger rod, wherein the thumb pad and the plunger rod are configured to transition from a first state to a second state, wherein at the first state, the plunger rod is prevented from moving in a proximal direction, and at the second state, the plunger rod moves freely in a proximal direction.

The invention according to the present document discloses a device 1 configured for conveying a toxic aerosol from a drug contained in a syringe (S) or in a vial (F) toward a suction pipe, comprising a cylindrical hollow element comprising an inner space configured for accommodating a syringe so that the inner walls of said space slidingly adhere to the outer walls of the syringe barrel, provided with a proximal end 2.10 which includes an opening 2.6 configured in such a way as to allow the insertion of a syringe barrel, and a flange configured for accommodating a syringe flange, and a distal end 2.11 which includes an opening 2.7 configured in such a way as to allow the cone, fitting, and needle of said syringe to pass through, and a cap configured for being connected to said cylindrical hollow element present in two configurations, one suitable for administering a drug and another suitable for taking a drug from a vial, in particular a drug potentially releasing a toxic aerosol.

The document also discloses a method for using the kit and the device according to the invention.

An autoinjector includes a housing, a product container, a torsion spring, a drive element, and a propulsion element. In order to discharge liquid out of the product container, the torsion spring rotates the drive element, and the rotating drive element produces a propulsive movement of the propulsion element and of a piston in the product container. A rotation sensor is configured for an alternating continuous detection of at least two rotational positions per revolution of the drive element during the discharge process, and a processor unit is configured for determining the axial position of the piston in the product container from the detected rotational positions.

An autoinjector for discharging one or more liquid products includes: a housing containing a multichamber product container, which includes a syringe body and an injection needle rigidly arranged at the distal end of the syringe body. The syringe body includes a first chamber for a first liquid product, a second chamber for a second liquid product, and a bypass for fluidically connecting the first chamber and second chamber. The bypass is formed in or on the syringe body in the form of a curved section protruding radially outwards, and two plungers are arranged in the syringe body in an axially movable manner.

A safety needle device is disclosed having a housing configured to couple to a syringe, the housing having a proximal end, a distal end, and a housing body. A first guide path, a second guide path and a third guide path may be disposed on the housing body. A needle hub is disposed on the proximal end of the housing and a needle cannula is attached to the needle hub. The device having a retractable sheath configured to move between an initial position, a retracted position and an extended position with respect to the housing, wherein the initial position partially exposes a distal tip of the needle cannula, the retracted position fully exposes the needle cannula, and the extended position fully covers the distal tip of the needle cannula. The retractable sheath also may have a guide element. The first, second and third guide paths are configured to slidingly receive the guide element. The device also having a first locking member, a second locking member, a rotating cam disposed in the housing body, and a spring element to bias the retractable sheath to an extended state to cover the distal end of the needle cannula upon completion of an injection.

A passive safety needle shield (300) is provided. The needle shield comprises a base (302) fixed to a proximal end of a needle, and an enclosure housing (304) initially disposed at a distal end of the needle, and enclosing the end of the needle. A hinged arm (306) connects the base (302) and the enclosure housing (304). The enclosure housing (304) is slidable along the needle length, and the hinged arm (306) flexes to permit the enclosure housing (304) to move along the needle as the needle is inserted into a user, thereby hiding the needle end, and providing support to the needle to avoid bends or buckles in the needle. The hinged arm (306) is biases in the initial position so that the enclosure housing (304) returns to the end of the needle as the needle is withdrawn.

The invention relates to an autoinjector 59 for administering a fluid medicament to a subject comprising: a housing 1 for receiving a cartridge holder; a driver assembly 8; the driver assembly on actuation may move the cartridge 3 forward in the cartridge holder 2; a needle cover 4 may be coupled to the housing wherein the needle cover 4 travels in a linear or translational movement; said needle cover 4 is adapted to protect a needle when the needle cover may be in first locking position 17 and second locking position 18; the linear or translational movement may be achieved by a cam profile 13 and a cam follower 14; the cam profile 13 may be provided on outside surface of housing and the cam follower 14 located between the needle cover 4 and the housing 1; a first biasing member 15; and a second biasing member 16 configured to bias the cartridge 3 and the needle cover 4 respectively; and a safety cap 11 to control the actuation of the autoinjector. The needle cover 4 further comprises a sleeve 91 or sleeve 92 which prevents or inhibits the obstruction of the movement of needle cover 4 when the user accidentally hold the needle cover 4 during actuation of the autoinjector.