Devices for delivering a controlled concentration of an agent are provided. The device includes a reservoir for the agent and a flow control portion operably connected to the reservoir. The device also includes a valve for releasing the agent from the flow control portion and a pump for flowing air to mix with the agent released by the valve and for flowing the agent and air mixture out of the device. Methods of delivering a vaporized agent to a subject are also provided. The methods include storing a liquid agent in a reservoir of a device and flowing the agent into a flow control chamber to change the agent to a gas. The methods also include mixing the agent in gas form with air and flowing the agent and air mixture out of the device to be delivered to a subject.

A non-invasive ventilation system may include at least one outer tube with a proximal lateral end of the outer tube adapted to extend to a side of a nose. The at least one outer tube may also include a throat section. At least one coupler may be located at a distal section of the outer tube for impinging at least one nostril and positioning the at least one outer tube relative to the at least one nostril. At least one jet nozzle may be positioned within the outer tube at the proximal lateral end and in fluid communication with a pressurized gas supply. At least one opening in the distal section may be adapted to be in fluid communication with the nostril. At least one aperture in the at least one outer tube may be in fluid communication with ambient air. The at least one aperture may be in proximity to the at least one jet nozzle.

Cartridges for vaporizer devices are provided. In one exemplary embodiment, the cartridge can include first and second storage chambers each configured to hold a respective fraction of a vaporizable material, a vaporization chamber that includes an elongate member that is in fluid communication with the first and second storage chambers and configured to receive the vaporizable material, a magnetic element disposed within a channel of the elongate member, and a conductive element that is configured to generate a first motive force to drive the magnetic element between first and second positions and further configured to substantially vaporize the vaporizable material within the elongate member. Vaporizer devices are also provided.

An aerosol-generating device is provided, including: a storage portion to store an aerosol-forming substrate and having an outer housing and an internal passageway, the storage portion forming a reservoir for the substrate between the outer housing and the internal passageway; a vaporizer being at least partially inside the internal passageway; and a porous interface at least partially lining the internal passageway to convey the substrate from the storage portion towards the vaporizer, the device being electrically operated and the vaporizer including an electric heater to heat the substrate, the heater including first and second cylindrical electrical connection portions, and a cylindrical heating filament between the first and the second portions, the first and the second portions being in the form of hollow tubes, the cylindrical shape of the first and the second portions and the filament defining a cylindrical bore with an air flow route therethrough.

Dispensing systems for a ventilator circuit having a ventilator flow circuit with a normal inhalation flow path with a heat and moisture exchanger (HME), a flow sensor in communication with the ventilator circuit, an automated drug dispensing system with an actuator and a pressurized canister residing upstream of the HME, a bypass inhalation flow path residing downstream of the pressurized canister, and at least one electromechanical valve residing in the inhalation flow path to selectively open the valve which can be normally closed to define a closed bypass path. At least one controller opens the at least one electromechanical valve to open the bypass inhalation flow path and close the normal inhalation flow path through the HME only when the flow sensor indicates air flow is in an inhalation direction. Once the valve is open, the actuator dispenses medication through the bypass inhalation flow path to the patient.

An electronic device for producing an aerosol for inhalation by a person includes a mouthpiece, a liquid container, and a mesh assembly having a mesh material and a piezoelectric material. The mesh material is in contact with a liquid of the container. The mesh material is configured to vibrate when the piezoelectric material is actuated, whereby the aerosol is produced. The aerosol may be inhaled through the mouthpiece. The device also includes circuitry and a power supply for actuating the mesh assembly. The mouthpiece, the container, and the mesh assembly are located in-line along a longitudinal axis of the device between opposite longitudinal ends of the device, with the mesh assembly extending between and separating the mouthpiece and the container. The mesh material has a rigidity that is sufficient to prevent oscillations of varying amplitudes during actuation of the piezoelectric material of the mesh assembly for consistently producing the aerosol.

A device for determining a patient component of an exchange of gas of a patient being ventilated, a measuring device or ventilation device with such a device for determining a patient component of an exchange of gas of a patient being ventilated, a process as well as to a computer program determine a patient component of an airway flow of a ventilation gas of a patient being ventilated. A determination of a patient component of an airway flow of a ventilation gas of a patient being ventilated are described. The determination includes an implementation with a signal processor, of forms a high-pass characteristic.

Monitors for evaluating airway procedures, particularly in a pre-hospital environment, are described herein. In an example method, an airway parameter of an individual receiving assisted ventilation is detected by an airway sensor. A monitor determines a metric based on the airway sensor. Further, the monitor performs an action based on the metric.

A capsule for a heat-not-burn (HNB) aerosol-generating device may include a first heater, a second heater, and a frame sandwiched between the first heater and the second heater, and a cannabinoid-containing material. The frame may define open spaces therein and have a rigidity that is adequate to support the first heater and the second heater. The open spaces within the frame may be interconnected and sized for aerosol-permeability and capillary action.

Apparatus and methods for generating an inhalable medium are disclosed. An apparatus includes a container for holding a liquid, a heater for volatilizing liquid held in the container to generate a flow of at least one of a vapor and an aerosol in use, and a receptacle for receiving material. The receptacle is located adjacent to the heater such that in use, material received in the receptacle is heated by the heater. One or more constituents of material received in the receptacle in use are mixed with the flow of at least one of a vapor and an aerosol in use to produce the inhalable medium.