A supply arrangement (100) and a process supply a medical device (50, 90) with a supply gas mixture. The supply gas mixture includes a carrier gas and an anesthetic and is generated by an anesthetic dispenser (3). A carrier gas mixing unit (9) generates the carrier gas from at least two carrier gas components. A carrier gas switch having a regular outlet and a discharge outlet selectively directs carrier gas components to the carrier gas mixing unit or to a discharge line (35). A gas mixture switch (6), having a regular outlet (41) and a discharge outlet (42) selectively directs the supply gas mixture to the medical device or to the discharge line (35). An anesthetic concentration sensor (5.1, 5.2) measures a concentration of anesthetic in the generated gas mixture. A control unit (2) controls the gas mixture switch based on measured concentration within or outside a predefined range.

Methods and systems are provided for anesthetic agent leakage diagnostics. In one embodiment, a method for diagnosing leaks in an anesthetic vaporizer includes calculating a leakage rate based on measurements of an anesthetic agent level in a sump of the anesthetic vaporizer, the measurements received from a fluid level sensor at a first time and a second time, and outputting a maintenance alert responsive to the leakage rate exceeding a threshold.

The present invention provides for systems and methods for inhaled CO therapy to prevent, attenuate, or delay processes that accelerate the loss of organ or tissue function, thereby increasing the lifespan of transplanted organs or tissues, or slowing the decline of native organs or tissues, or delaying the need for replacement of diseased native organs with organ transplants. Such biological processes that are prevented, attenuated, or delayed include chronic persistent inflammation, fibrosis, scarring, as well as immunologic or autoimmune attack.

A sedation device has a housing divided internally into a ventilator chamber and an associated evaporator chamber which overlap and are separated by a filter mounted between the chambers and forming a common gas-permeable dividing wall between the chambers. An inlet port is provided at one end of the ventilator chamber at a top of the housing for connection to a patient ventilator in use. An outlet port on the evaporator chamber can be connected via a breathing tube to a patient. An evaporator is mounted within the evaporator chamber for delivery of a volatile sedative into the evaporator chamber during use.

A ventilation system includes an electrochemical filter for depleting alkyl phenols, especially 2,6-diisopropyl phenol, in breathing gas. A method uses the filter for removing alkyl phenols, especially 2,6-diisopropyl phenol, from breathing gas.

Provided herein are compositions, methods, uses, and articles of manufacture for iodine treatment on mucosal membranes, and treatment of respiratory pathogens in this way—e.g., by inhalation and combined with the evaporation of steam. In certain embodiments, iodine treatment encompasses administration of compounds that release molecular iodine and/or physiologically active iodine-containing compounds.

Methods and systems are provided for delivering anesthetic agent to a patient. In one embodiment, an anesthetic vaporizer includes a sump configured to hold a liquid anesthetic agent; an ultrasonic transducer coupled to a bottom of the sump and at least partially disposed within the sump; a vaporizing chamber fluidically coupled to the sump; and a heating element coupled to the vaporizing chamber and configured to increase a temperature of a surface disposed within the vaporizing chamber.

An anesthetic dispenser (100) includes an anesthetic tank (7) and a mixing unit (9) that mixes an anesthetic from the anesthetic tank with a carrier gas. Liquid anesthetic (Nm) can be refilled into the anesthetic tank through a refill opening (6). In one operating mode, a specified operating pressure is maintained. A closure (16) is moveable from a closed position via an intermediate position to an open position and closes the refill opening in both the closed position and the intermediate position. When the closure is moved from the closed position to the intermediate position, a transition time period elapses. A position sensor (22) detects the event that the closure has been moved out of the closed position. In response to this detection, pressure in the anesthetic tank is lowered during the transition period to a refill pressure that is still above ambient pressure. The closure is then opened.

A method of treating a human subject which is effected by inhalation of gaseous nitric oxide, the method comprising a first treatment period comprising administering gNO by inhalation over a period of about at least 5 days, wherein the first treatment period is followed by a second treatment period comprising administering gNO by inhalation over a period of at least 3 months. The method can be utilized for treating a human subject suffering from, or prone to suffer from, a disease or disorder that is manifested in the respiratory tract, or from a disease or disorder that can be treated via the respiratory tract.

An electronic vaporizer system includes an anesthetic sump containing anesthetic agent, a vaporizer unit that vaporizes the anesthetic agent from the sump and delivers the vaporized agent to a patient breathing circuit, and a gas sensor configured to measure end tidal concentration of the anesthetic agent and exhalation gasses from the patient. A control system is configured to receive the measured end tidal concentration of anesthetic agent and compare the measured end tidal concentration to a desired end tidal concentration to be maintained for the patient. The vaporizer unit is then automatically controlled to deliver an amount of vaporized agent to the patient based on the comparison.