In various aspects, the present disclosure pertains to methods of treating or preventing bleeding at a tissue site comprising applying a chitosan powder composition to the tissue site. In various aspects, the present disclosure pertains to chitosan powder compositions for application to a tissue site, where the powder compositions comprise a chitosan salt, a crosslinked chitosan, a derivatized chitosan, or a combination thereof. In various aspects, the disclosure pertains to catheter assemblies, which are preloaded with a chitosan powder composition and which are configured to deliver the chitosan powder composition a tissue site.

Described herein is a liquid embolic delivery device designed to minimize excess embolic solvent buildup therein. The liquid embolic delivery device generally comprises an outer catheter, an inner catheter that is longitudinally moveable within the outer catheter. The inner catheter is used for an initial embolic solvent flush and to deliver liquid embolic, while the outer catheter is used to remove excess solvent.

A suction catheter assembly structured to be movably positioned within a lumen of the body including an elongated base having a channel extending interiorly along the length thereof and further structured to connect the channel to a source of negative pressure. A tip is fixedly or removably connected to a distal end of said base and includes an inlet port and a flow path disposed in fluid communication with the channel. A viewing structure is connected to and movable with the base and is oriented relative thereto to define a line of sight providing observation of a path of travel of said base within the body lumen or medical tubing and is disposed laterally outward from at least a majority of a length of said flow path and the inlet port in substantially aligned, parallel relation to a central axis of said channel.

A catheter for treatment of a defect internal of a human or animal body. The catheter may comprise a tube adapted for insertion into the body; an applicator disposed within and moveable relative to the tube; and a porous medium attached to the applicator; wherein the porous medium is capable of fitting inside the tube, whereby the applicator can be controlled at a proximal end of the tube to deploy the porous medium from a distal end of the tube so as to treat the defect.

Guidewires and methods of use of guidewires having improved atraumatic tips that can distribute force to lessen trauma as well as anchor the guidewire to facilitate improved catheter exchange.

An aspiration catheter is provided including a proximal section and a distal section extendable through the proximal section. A vacuum transfer tool may be coupled to a proximal end of the proximal section. The vacuum transfer tool may include a proximal transfer tube and a distal transfer tube, each having an aspiration port in communication with a vacuum source. The proximal transfer tube may be removably received within a proximal end of the distal transfer tube. The proximal transfer tube may maintain a vacuum around the proximal end of the distal section of the catheter such that when the distal section is removed by decoupling the proximal and distal transfer tubes, the vacuum within the distal transfer tube and proximal section of the catheter is maintained, preventing the escape of any clots.

An aspiration catheter is provided including a proximal section and a distal section extendable through the proximal section. A vacuum transfer tool may be coupled to a proximal end of the proximal section. The vacuum transfer tool may include a proximal transfer tube and a distal transfer tube, each having an aspiration port in communication with a vacuum source. The proximal transfer tube may be removably received within a proximal end of the distal transfer tube. The distal section of the catheter may be inserted into the proximal section through the proximal transfer tube. The proximal transfer tube may maintain a vacuum around the proximal end of the distal section of the catheter such that when the distal section is removed by decoupling the proximal and distal transfer tubes, the vacuum within the distal transfer tube and proximal section of the catheter is maintained, preventing the escape of any clots.

A catheter or shaft, such as a distal access support or aspiration catheter, is provided that is configured to be advanced at least partially within a patient. The catheter or shaft may include a flexible and hollow shaft including a proximal end and a distal end. The flexible and hollow shaft may include a slotted portion with a plurality of slotted openings, the slotted portion including a first segment with a first pattern of slotted openings and a second segment extending proximally relative the first segment with a second pattern of slotted openings different from the first pattern.

Retrieval of material from vessel lumens can be improved by electrically enhancing attachment of the material to the thrombectomy system. The system can include a catheter having a distal portion configured to be positioned adjacent to a thrombus in a blood vessel, an electrode disposed at the distal portion of the catheter, and an interventional element configured to be delivered through a lumen of the catheter. The electrode and the interventional element are each configured to be electrically coupled to an extracorporeal power supply.

A suction catheter for fragmenting and removing obstructive material and thrombus from the body or other body cavities that comprises a tube-like body with a proximal and distal end and a pressure lumen and discharge lumen formed in the catheter body. At the distal end of the catheter is a suction opening adjacent to the opening of the nozzle injector formation. At the proximal end of the catheter the lumens are connected to an inlet port and a discharge outlet. A hub structure is coupled to the proximal end of the catheter tubular body and includes a pressure lumen for connecting a fluid source to the pressure inlet. At the proximal end of the tubular catheter a discharge lumen is connected at the proximal hub to a discharge reservoir. The suction port at the distal end of the catheter may be formed into a separate lumen within the catheter body and may include a guidewire lumen.