An example catheter assembly includes a first catheter body portion defining a first lumen and a plurality of sidewall openings open to the lumen and configured to at least one of introduce fluid into a patient or remove fluid from the patient. The catheter assembly further includes a second catheter body portion defining a second lumen, a first cuff proximal to a distal end of the first catheter body portion, a second cuff distal to a proximal end of the second catheter body portion, and a connector configured to mechanically connect the first and second catheter body portions between the first and second cuffs and to fluidically connect the first and second lumens. A distance between the first and second cuffs is modifiable by at least modifying one of a length of the first catheter body portion or a length of the second catheter body portion.

An indwelling pleural catheter system comprises an indwelling catheter device (2) comprising a catheter tube (7) with a fenestrated distal end (7A) configured to reside in the pleural cavity of a subject and a connection hub (10) fluidically coupled to a proximal end (7B) of the catheter tube, a skin anchoring member (3) to anchor the connection hub (10) to the skin of the subject, and optionally a detachable ambulatory suction module (4) configured for detachable attachment to the connection hub (10). The suction module (4) comprises a fluid inlet (19) configured for fluidic coupling to the catheter tube (7) through the connection hub (10) and a fluid outlet (20) configured for detachable fluidic coupling to a pleural fluid drainage system (5) to drain pleural fluid through the detachable ambulatory suction module. The detachable ambulatory suction module is configured to exert a negative pressure in the catheter tube upon detachment of the pleural fluid drainage system from the suction module. Treatment of pleural effusion using the system of the invention is described. An indwelling catheter system for draining fluid from the peritoneal cavity, and methods of treating ascites, is also described.

Systems and methods for delivering a drug or other therapy over an extended period of time (e.g., several hours, days, weeks, months, years, and so forth) are disclosed herein, as are systems and methods for monitoring various parameters associated with the treatment of a patient. Systems and methods are also disclosed herein that generally involve CED devices with various features for reducing or preventing backflow.

In some examples, a catheter assembly includes a catheter including an elongated catheter body defining a lumen, a first cuff and a second cuff. The first cuff includes a first cuff body comprising a material configured to promote epidermal tissue growth around or within the first cuff and an adhesive configured to adhere the first cuff body to an outer surface of the elongated catheter body at a first cuff position selectable by a user. The second cuff includes a second cuff body comprising the material configured to promote epidermal tissue growth around or within the second cuff body and an adhesive configured to adhere the second cuff body to the outer surface of the elongated catheter body at a second cuff position selectable by the user. A distance between the first and second cuff positions is customizable by the user based on a patient.

A material includes a metallic, nanoporous structure having a plurality of nanopores having a porosity that allows passage of insulin but not IgG. The metallic nanoporous structure includes titanium, 316L stainless steel and may have a textured nano-sericeous surface. A nanoporous bicontinuous structure can be integrated with nanopores.

The invention relates to a cannulation robot for the automated affixing of a cannula to a patient. The cannulation robot comprises a fixing apparatus for affixing the cannula to the patient by means of an adhesive carrier. The cannulation robot comprises a positioning device designed to position a cannula holder of the cannula to an area of the patient's skin. The cannulation robot comprises an actuator device for a guide means, wherein the guide means is designed to guide the adhesive carrier to said skin area. The actuator device is designed to activate the guide means and thereby move the adhesive carrier by means of the guide means toward the skin area, wherein the adhesive carrier contacts the skin area as a result of the movement and adheres to same as well as is disposed such that it is connected to the cannula at least after being adhered.

A low-profile access port for subcutaneous implantation within a patient. The access port can include a set of receiving cups which can be placed in fluid communication with a catheter. The set of receiving cups can provide a greater skin surface with which to access the port to avoid repeated penetrations at a single locus, such as during consecutive dialysis treatments. The access port can alternatively include needle penetrable arms or elongate chambers that also have a slim, low profile. The access port can include a needle guide to direct subsequent needle access to different insertion points to permit healing at the previous insertion points. The access port can be formed of a modular construction with a first conduit, a second conduit, and an outer shell. The outer shell can include a proximal portion and a distal portion. The access port can include a stem assembly and a locking member.

An external end device has a casing (4), including a base (5), in which a distal opening (12) is formed which receives a funnel-shaped septum (14) having a tube trunk (140). Inside the tube trunk (140) the catheter (3) is connected to the distal section (16) of the fitting (15). A tubular coating (2) has a proximal end adapted to be grafted onto the tube trunk (140) and a distal end coaxially adhering to the catheter (3). A pair of bands (90, 91) of tissue-ingrowth material is fixed on the tubular coating (2), and an anchor ring (92), equipped with anchoring means, is sandwiched between the bands (90, 91).

A modular tunneled catheter is provided that allows lumen length and cuff positioning to be adjusted based on the size of a patient. This catheter should be useful for any patient who would benefit from customized fitting of a catheter to their measurements. Methods of using the modular catheter for hemodialysis, peritoneal dialysis, and fluid drainage, including drainage of plural effusions from the lungs or malignant ascites from the abdomen are also described.

To reduce the suffering of the patient and enable easier removal of excess fluid such as pleural effusion fluid from the chest space, the disclosure provides a catheter for chest drainage intended for removal of excess fluid from a chest space of a living body and to be placed in the living body in such a manner as to extend from an inside of the chest space to an outside of the living body. The catheter includes a passage member formed of a flexible sheet and having a passage through which the excess fluid is to be drained, and an indwelling member formed of an elastic body and provided at a proximal end of the passage member. The indwelling member has an inlet that allows the excess fluid to flow through. The indwelling member includes a retaining portion spreading in a flange shape and being retainable at a chest wall.