Disclosed is a drug injection device that is fixedly implanted a patient's skull and scalp to inject a drug. The disclosed drug injection device includes a main body that is fixedly implanted in contact with a skull and has an internal hole; a main body fixing part that has an internal hole to be adjacent to the main body and is fixedly coupled to the main body; a movable part that is positioned between the main body and the main body fixing part, has a drug injection hole at a central part thereof, and is able to change its direction to a target point; a sealing part that is configured to seal the drug injection hole of the movable part, into which an injection needle for injecting a drug is inserted; a movable lid part that is positioned above the sealing part to close and fix the movable part, prevents the sealing part from being separated and escaping outside, and identifies an implantation position of the drug injection device to guide a point for repeated administration; and at least two fastening members that fasten an upper part of the main body and an upper part of the main body fixing part to the skull, in which the main body includes a support part that is positioned above the skull for support, an outer diameter of the support part is smaller than an outer diameter of the main body fixing part and is greater than an outer diameter of the movable part, and the main body and the main body fixing part are adjacently coupled to each other to accommodate and fix the movable part in the internal hole of the main body.

An access port can be connected to a catheter and includes a port body including a liquid storage portion and a diaphragm body covering the liquid storage portion. The port body includes a connection passage connected to the liquid storage portion and allows the liquid storage portion to communicate with the inside of the catheter. In the cross-section along the axial direction of the connection passage at the connection position where the connection passage is connected to the liquid storage portion, the length in the direction perpendicular to the axial direction between the surface of the diaphragm body on the side opposite to the liquid storage portion and the inner surface of the liquid storage portion gradually decreases as it proceeds away from the connection position in the inclined region exceeding half of the liquid storage portion along the axial direction.

A catheter may include an elongate body extending from a proximal end to a distal end and defining a lumen; a push member mechanically coupled to the proximal end of the elongate body; and a slidable push grip disposed about an outer perimeter of the push member. The slidable push grip is controllably engageable with the push member. When the slidable push grip is in an engaged state with the push member, the slidable push grip transmits an axial force to the push member to enable the push member to transmit the axial force to the elongate body. When the slidable push grip is in a disengaged state with the push member, the slidable push grip is movable axially in at least one direction along a length of the push member while transmitting substantially no axial force to the push member.

Vacuum dressings with a guide tube are provided for implantable medical devices that inhibit infection associated with in-dwelling devices while encouraging healing of the incision around the device. The vacuum dressings mitigate pooling of fluids that harbor bacteria from between the outer diameter of an inserted implantable medical device and the inner diameter of a guide tube and also in the cylindrical gap, between the outer diameter of an inserted implantable medical device and the inner wall of the subcutaneous tunnel, which remains in fluid communication with skin microflora. Implantable medical devices may also illustratively include a variety of catheters, such as venous access, peritoneal dialysis, and other indwelling venous access catheters that require skin penetration; cannulas; Steinman pins; Kirschner wires; and cardiac assist device lines.

A vascular access device may include a housing, which may include a distal end, a proximal end, and a lumen extending through the distal end of the housing and the proximal end of the housing. The distal end of the housing may include a connector configured to couple to a catheter assembly. The vascular access device may include a bag, which may be coupled to the proximal end of the housing. The vascular access device may include an instrument and a pincher disposed within the bag. The pincher may be configured to pinch the instrument to move the instrument distally through the lumen of the housing and into the catheter assembly.

A port catheter includes a port housing and a port chamber formed in the port housing and closed by a septum. The port catheter also includes a first catheter connection communicating with the port chamber for the connection of a first catheter, a second catheter connection for connecting a second catheter connected to an infusion pump and supplying a fluid to the port catheter from the infusion pump, and a third catheter connection communicating with the second catheter connection for connecting a third catheter which discharges the fluid supplied by the infusion pump.

The devices, systems, and methods include a catheter including a flexible tube having a proximal end and a distal end, the catheter defining a lumen extending from the proximal end to the distal end. The tube defines a plurality of slits. The distal end of the tube includes an atraumatic tip configured to be advanced through an opening in a skull to a target treatment site within the brain. A detachable connector is attached to the proximal end of the tube. Upon delivery of a fluid to the catheter from an external fluid source, the slits in the tube are responsive to pressure of the fluid within the catheter, by the slits opening to disperse the fluid from the lumen of the tube. The slits are responsive to a drop in pressure of the fluid within the catheter, by the slits closing.

The present invention relates to methods of transvascular retrograde access placement and to devices that facilitate these methods. For purposes of the present invention, transvascular retrograde access placement generally comprises the insertion of a vascular catheter into a central blood vessel through the puncturing of the central blood vessel from the inside of the central blood vessel with a needle or other similarly configured device, or a needle-tipped guidewire of the present invention, and exiting that needle from the patient through the skin rather than the traditional approach of inserting a needle from the outside of the skin surface to the inside of a blood vessel.

A surgical access assembly and method of use is disclosed. The surgical access assembly comprises an outer sheath and an obturator. The outer sheath and obturator are configured to be delivered to an area of interest within the brain. Either the outer sheath or the obturator may be configured to operate with a navigational system to track the location of either within the brain. Once positioned at a desired location, the obturator is removed, leaving a distal end of the outer sheath adjacent an area of interest, and creating a working corridor. Interrogation of the area of interest may be performed to evaluate a disorder and/or abnormality, as well as evaluate treatment regimes. Interventional devices may also be introduced to the area of interest, as well as a variety of treatments.

An apparatus for the uninterrupted administration of fluid to an animal body during clean blood collections is disclosed. Embodiments include an intravenous device defining a first fluid channel, wherein the first fluid channel is configured to selectively transport IV fluid to an animal body and draw a bodily fluid from the body, and a connection member configured to connect to a catheter to the first fluid channel and defining a concave distal end. A second fluid channel continuously provides IV fluid to a lumen coaxially located within the catheter. The concave surface is shaped to create a fluid flow pattern that quickly and completely removes residual bodily fluid remaining at the concave distal end. Embodiments include a concave surface defining an asymmetric funnel shape, a vertex of which is centered on the first fluid channel.