The disclosure relates to a subcutaneously implanted port device for establishing access to the vascular system of a patient requiring multiple blood treatments over an extended period of time. The systems, devices and methods disclosed herein may reduce miscannulation, promote intra-session hemostasis, and decrease the incidence of bacteremia and sepsis among other improvements and advantages. The devices include a port with a tapered seat for receiving an access tube, the first tapered seat having a proximal portion, a distal portion, and a conical section extending between the proximal portion and the distal portion; and an interface surface configured to engage a blood vessel or a vascular access catheter. The proximal portion of the tapered seat is configured to receive the access tube therethrough, and the tapered seat creates a mismatch fit with a diameter of the access tube when in use for an increase in flow during treatment.

A medical elongated body that is capable of improving convenience during use by a surgeon, and capable of preventing peeling, from a catheter main body, of a drug portion (a hydrophilic coating) containing metal ions and a drug when disposed on a wound site of a patient. An introducer sheath includes a tubular sheath configured to be percutaneously inserted into a blood vessel, and a hub connected to a proximal portion of the tubular sheath, in which the tubular sheath includes a first region and a second region located on a proximal side relative to the first region, the first region has a first hydrophilic coating having lubricity, the second region includes a groove portion extending from a distal side of the tubular sheath toward a proximal side of the tubular sheath, the groove portion having a second hydrophilic coating containing at least one of metal ions and a drug.

Provided herein is a system including, in some embodiments, a streamlined port and a port tunneler. The port includes a septum and a stabilizing element. The septum is disposed over a cavity in a body of the port, and the septum is configured to accept a needle therethrough. The stabilizing element is configured to stabilize the port in vivo and maintain needle access to the septum. The port tunneler includes an adapter and a release mechanism. The adapter is in a distal end portion of the port tunneler, and the adapter is configured to securely hold the port while subcutaneously tunneling the port from an incision site to an implantation site for the port. The release mechanism is configured to release the port from the adapter at the implantation site for the port.

An introducer assembly includes a plurality of selectable side holes through which a fluid can be delivered. In some examples, an introducer assembly includes an outer elongated body defining a plurality of outer body side holes and an inner elongated body defining a plurality of inner body side holes. The inner elongated body is configured to rotate relative to the outer elongated body between a first rotational orientation in which a first subset of outer body side holes aligns with a first subset of inner body side holes and the inner elongated body blocks fluid flow out of the outer elongated body through a second subset of outer body side holes, and a second rotational orientation in which the second subset of outer body side holes aligns with a second subset of inner body side holes and inner elongated body blocks fluid the first subset of outer body side holes.

An interface device for implantation in a subject includes a tissue integration layer and a crowning element. The tissue integration layer has a porous structure adapted for ingress of tissue to anchor the device when implanted. The crowning element is adapted for epidermal attachment when the device is implanted and is configured such that once implanted, part of the crowning element extends through the epidermis and is accessible from outside the subject's body. The porous structure of the tissue integration layer is interconnected for tissue ingress during implantation.

A method and apparatus are aimed to improve arteriovenous fistula maturation rate by treating the fistula with a crosslink agent solution (fixative solution). The fixative solution will crosslink proteins and biomolecules, allowing formation of crosslinks that stabilize or stable tissue structure. The method and apparatus will address factors that contribute to arteriovenous fistula maturation failure by stopping the neointimal hyperplasia growth after vascular injury and stabilizing the venous wall to prevent the lumen from narrowing.

A self-closing device for implantation within a patient's body includes base material including an inner surface area for securing the base material to a tissue structure, and a plurality of support elements surrounding or embedded in the base material. The support elements are separable laterally within a plane of the base material to accommodate creating an opening through the base material for receiving one or more instruments through the base material, and biased to return laterally towards a relaxed state for self-closing the opening after removing the one or more instruments. The device may be provided as a patch or integrally attached to a tubular graft or in various shapes.

A connector hub for a needle assembly, the connector hub comprising a first portion located at a first end section of the connector hub, the first portion comprising a first longitudinal axis, a second portion located at a second end section of the connector hub opposite the first end, the second portion comprising a second longitudinal axis, a medial portion located at a middle section of the connector hub between the first and second end sections, the medial portion comprising a medial longitudinal axis arranged at an angle relative to the first longitudinal axis, and arranged at an angle relative to the second longitudinal axis, and at least one insertion port located on the medial portion, wherein the insertion port comprises an insertion port longitudinal axis, wherein the insertion port longitudinal axis is arranged at an angle relative to the medial longitudinal axis.

A septum for a port is provided, the septum having a top wall and a side wall. The side wall can include a pressure-activated valve element for regulating the flow of fluid across the valve. The curvature of the side wall and the geometry of the sidewall and the housing can be tailored to bias the valve element to open at different pressures during infusion and aspiration. The side wall can also include an extended portion that can function as a suture wing for securing the port within a port pocket.

An intraosseous access system to access a medullary cavity includes a driver including an access assembly, a motor, and an energy source. The intraosseous access system further includes a sensor configured to detect a first input from one of the motor or the energy source. The intraosseous access system further including a processing unit, communicatively coupled with the sensor, configured to receive the first input from the sensor, and determine access to a medullary cavity. The processing unit can then modify operation of one of the motor and the energy source to automatically stop operation of the system and prevent backwalling.