The invention is directed to an inhaler device for inhalable liquids, in particular for the administration of inhalable volatile liquids such as halogenated volatile liquids, to a patient. According to particular embodiments, the inhaler device may include a liquid container for hermetically storing inhalable liquid; a wicking material for supporting inhalable liquid; a piercing member configured to pierce the liquid container, wherein the liquid container may be provided in a first position in which the piercing member does not engage the liquid container and inhalable liquid remains hermetically stored within the liquid container, and the liquid container may be displaced from the first position to a second position such that the piercing member pierces the liquid container to release inhalable liquid onto the wicking material, whereby during inhalation inhalable liquid vapor from the wicking material is delivered to the patient.

Dialysis is enhanced by using nanoclay sorbents to better absorb body wastes in a flow-through system. The nanoclay sorbents, using montmorillonite, bentonite, and other clays, absorb significantly more ammonium, phosphate, and creatinine, and the like, than conventional sorbents. The montmorillonite, the bentonite, and the other clays may be used in wearable systems, such as a wearable peritoneal dialysis system, in which a dialysis fluid is circulated through a filter with the nanoclay sorbents. Waste products are absorbed by the montmorillonite, the bentonite, and the other clays and the dialysis fluid is recycled to a patient's peritoneum. Using an ion-exchange capability of the montmorillonite, the bentonite, and the other clays, waste ions in the dialysis fluid are replaced with desirable ions, such as calcium, magnesium, and bicarbonate. The nanoclay sorbents are also useful for refreshing a dialysis fluid used in hemodialysis and thus reducing a quantity of the dialysis fluid needed for the hemodialysis.

A device for rapid detection of a tuberculosis lipoarabinomannan (TB-LAM) is provided. The device includes a pre-concentrator unit for concentrating the TB-LAM comprising: an ion-exchange medium comprising one or more ligands configured to capture the TB-LAM from the source biological sample, wherein the captured-TB-LAM is eluted from the ion-exchange medium as an eluate comprising a concentrated form of TB-LAM; a cassette; a lateral flow assay unit disposed in the cassette; and an integration unit attached to the pre-concentrator unit and the cassette. The integration unit is configured to operatively couple and de-couple the pre-concentrator unit and the cassette. The pre-concentrator unit and the lateral flow assay unit disposed in the cassette are in a fluidic communication in a coupled form. The device for rapid detection of TB-LAM further comprises a dilutor unit.

Systems, devices, and methods of the present disclosure assist with management of tubes and hoses during surgical procedures. The systems, devices, and methods provide for the proper opening and closing of tubes to facilitate performance of steps in a surgical procedure. Systems, devices, and methods of the present disclosure control fluid delivery to and from a medical device, including devices for tissue processing and cleaning.

Dialysis is enhanced by using nanoclay sorbents to better absorb body wastes in a flow-through system. The nanoclay sorbents, using montmorillonite, bentonite, and other clays, absorb significantly more ammonium, phosphate, and creatinine, and the like, than conventional sorbents. The montmorillonite, the bentonite, and the other clays may be used in wearable systems, in which a dialysis fluid is circulated through a filter with the nanoclay sorbents. Waste products are absorbed by the montmorillonite, the bentonite, and the other clays and the dialysis fluid is recycled to a patient's peritoneum. Using an ion-exchange capability of the montmorillonite, the bentonite, and the other clays, waste ions in the dialysis fluid are replaced with desirable ions, such as calcium, magnesium, and bicarbonate. The nanoclay sorbents are also useful for refreshing a dialysis fluid used in hemodialysis and thus reducing a quantity of the dialysis fluid needed for the hemodialysis.

An isolation hood for respiratory treatment is disclosed. The isolation hood may include a head enclosure defining an interior volume configured to receive the head of a patient, and a neck seal configured to couple the head enclosure to a neck of the patient. The isolation hood may include an inlet port configured to be coupled to a distal end of a treatment source tube and to a first end of a treatment delivery tube, and an outlet port configured to be coupled to an inline particle filter configured to permit air to flow through the head enclosure. The neck seal and the inline particle filter are each configured to prevent viral/bacterial aerosolization outside the hood. The inlet and outlet ports may be attached to respiratory tubing and non-invasive ventilatory equipment to permit aerosol-generating procedures within the hood while preventing viral/bacterial aerosolization outside the hood.

A filter adaptor includes a body that defines an internal passageway disposed between an inlet and an outlet, the passageway configured to permit passage of a fluid in a first direction defined by the inlet and the outlet; and a filter disposed within the passageway and oriented to define a volumetric direction that is different than the first direction. Another filter adaptor includes a body that defines an internal passageway disposed between an inlet and an outlet, and a filter disposed within the passageway, wherein the filter comprises a gelling absorbent material that, when in a dry state, is permeable to gas and that, when contacted by an aqueous fluid, converts to a gel. Such filter adaptors may be used for negative pressure wound therapy, dressing, or as syringe filters.

A filter adaptor includes a body that defines an internal passageway disposed between an inlet and an outlet, the passageway configured to permit passage of a fluid in a first direction defined by the inlet and the outlet; and a filter disposed within the passageway and oriented to define a volumetric direction that is different than the first direction. Another filter adaptor includes a body that defines an internal passageway disposed between an inlet and an outlet, and a filter disposed within the passageway, wherein the filter comprises a gelling absorbent material that, when in a dry state, is permeable to gas and that, when contacted by an aqueous fluid, converts to a gel. Such filter adaptors may be used for negative pressure wound therapy, dressing, or as syringe filters.

An isolation hood for respiratory treatment is disclosed. The isolation hood may include a head enclosure defining an interior volume configured to receive the head of a patient, and a neck seal configured to couple the head enclosure to a neck of the patient. The isolation hood may include an inlet port configured to be coupled to a distal end of a treatment source tube and to a first end of a treatment delivery tube, and an outlet port configured to be coupled to an inline particle filter configured to permit air to flow through the head enclosure. The neck seal and the inline particle filter are each configured to prevent viral/bacterial aerosolization outside the hood. The inlet and outlet ports may be attached to respiratory tubing and non-invasive ventilatory equipment to permit aerosol-generating procedures within the hood while preventing viral/bacterial aerosolization outside the hood.

Systems, devices, and methods of the present disclosure assist with management of tubes and hoses during surgical procedures. The systems, devices, and methods provide for the proper opening and closing of tubes to facilitate performance of steps in a surgical procedure. Systems, devices, and methods of the present disclosure control fluid delivery to and from a medical device, including devices for tissue processing and cleaning.