Devices for delivering a controlled concentration of an agent are provided. The device includes a reservoir for the agent and a flow control portion operably connected to the reservoir. The device also includes a valve for releasing the agent from the flow control portion and a pump for flowing air to mix with the agent released by the valve and for flowing the agent and air mixture out of the device. Methods of delivering a vaporized agent to a subject are also provided. The methods include storing a liquid agent in a reservoir of a device and flowing the agent into a flow control chamber to change the agent to a gas. The methods also include mixing the agent in gas form with air and flowing the agent and air mixture out of the device to be delivered to a subject.

A device for injecting a therapeutic agent into an ocular implant at least partially implanted in an eye including an injection lumen providing a pathway for injecting the therapeutic agent into the implant; an outlet lumen providing a pathway for pre-existing fluid in the ocular implant to exit the implant; and a collection chamber fluidly coupled to the outlet lumen that provides a first fluid outflow resistance and a second fluid outflow resistance. The first fluid outflow resistance is lower than a first resistance to outflow of the implant. The second fluid outflow resistance is greater than a force imparted onto the implant by intraocular pressure of the eye. Injection of therapeutic agent into the implant via the injection lumen causes the pre-existing fluid to exit the implant and enter the collection chamber via the outlet lumen and causes a second pre-existing fluid to displace from the collection chamber.

Embodiments of the present invention provide a device and a method for treating at least one of hypertension, pulmonary arteries, diabetes, obesity, heart failure, end-stage renal disease, digestive disease, urological disease, cancers, tumors, pain, asthma or chronic obstructive pulmonary disease by delivering an effective amount of a formulation to a tissue. In embodiments of the present invention, the formulation may include at least one of a gas, a vapor, a liquid, a solution, an emulsion, or a suspensions of one or more ingredients. In embodiments of the present invention, amounts of the formulation and/or energy are effective to injure or damage tissue, nerves, and nerve endings in order to relieve disease symptoms.

A gas mixing system for providing mixed gas for intraocular injection. In some embodiments, a first fixed-volume chamber is automatically purged and filled with gas from a first gas supply input, to a first predetermined pressure. A second fixed-volume chamber is purged and filled with gas from a second gas supply input, to a second predetermined pressure. The first and second predetermined pressures are determined based on a desired concentration of gases in the final mix, and the respective volumes of the first and second fixed-volume chambers and of a third fixed-volume chamber. Gas from the first fixed-volume chamber is then allowed to mix with gas in the third fixed-volume chamber, which was previously purged. Next, gas from the second fixed-volume chamber is allowed to mix with gas in the third fixed-volume chamber. Finally, the mixture of gases in the third fixed-volume chamber is expressed into an intraocular syringe.

One larger [1] and one smaller tube [2], forming a functional unit with the smaller tube [2] positioned within the larger tube [1], both tubes are relocatable and demountable, both tubes with an aperture [3 and 4] at both ends, at least one aperture [5] being provided in the wall of the outer tube located at a distance of about between 1 mm and 10 cm from the tip [6], or several apertures positioned in a segment of 1-250 mm from the tip, wherein the diameter of the single aperture is between 70% and 120% of the inner diameter of the outer tube [1], or in case of several apertures, for each aperture 30-60% of the inner diameter of the outer tube, wherein the outer diameter of the inner tube is between 0.6 mm and 2.0 mm (F2 to F6), the outer diameter of the outer tube is between 1.3 mm and 3.6 mm (F4 to F11), and the distance between the outer wall of the inner tube and the inner wall of the outer tube is between 0.1 mm to 3.0 mm.

A method for preventing or treating an arrhythmia including administering an effective amount of hydrogen to a patient in need thereof.

A medicine vaporizer apparatus comprises a base with an upwardly extending heating element disposed within a rigid tube. Air is drawn into the rigid tube through an aperture in the rigid tube below the heating element and directed over the heating element to then be drawn through a flexible tube and through a filter or screen comprising an amount of medicine. Heated air flows over the amount of medicine and vaporizes the same, wherein the medicine is thereafter drawn into the lungs of a patient pulling the air therethrough with his or her mouth. Thermal separation and cooling of various parts prevents accidental injury to users and provides an inert air path for the air therethrough. The apparatus further provides controlled incineration and/or vaporization of the medicine.

Antiseptic agent delivery systems and methods are provided, one such system comprising: a reservoir configured to store an antiseptic solution, wherein the antiseptic solution comprises an aqueous solution of hypochlorous acid; an ultrasound generator coupled to the reservoir, wherein the ultrasound generator vaporizes the antiseptic solution into an antiseptic vapor; a nozzle to direct the antiseptic vapor to an affected area; and a housing coupled to the reservoir and the nozzle, wherein the housing comprises a panel to control the ultrasound generator.

There is provided a colon cleaning device comprising: a tube through which liquid and fecal matter are removed from a colon of a patient, the tube having a longitudinal axis; a cleaning head positioned at the distal end of the tube, the cleaning head having at least one opening coaxial with the longitudinal axis, the at least one opening sized for fecal matter to enter the interior of the cleaning head from the colon; at least one disassembly element disposed within the cleaning head; and an actuating mechanism which actuates the disassembly element to perform sweeping displacement inside the cleaning head so that the at least one disassembly element rotates around the longitudinal axis to slice through the fecal matter; wherein the cleaning head and the tube are sized and shaped to be displaced along the colon of a patient.

A medical tube is provided. The medical tube includes a hollow body and a gas conduit formed inside the hollow body for transporting gases. A material of the hollow body is a thermoplastic polyester elastomer. Based on a total weight of the thermoplastic polyester elastomer being 100 wt %, the thermoplastic polyester elastomer includes 50 wt % to 70 wt % of hard segments and 30 wt % to 50 wt % of soft segments.