A powered handpiece for imparting to a cannula of a medical device a reciprocal movement of amplitude (Δx) along a longitudinal axis (X) is provided. A housing (1) at least partially encloses a hollow tube (2) extending along the longitudinal axis (X) between an inlet end (2i) and an outlet end (2o), the inlet end (2i) being configured for coaxially coupling the hollow tube (2) to a hollow cannula (10). A ring (3) rigidly is coupled to the hollow tube (2) and has an opening (3o) defined on a plane (X, Y), having a length, L, Y ⊥X. A cam (4) mounted on a rotation axle (4r) parallel to a second transverse axis (Z) normal to the plane (X, Y) (i.e., X ⊥Y ⊥Z), offset from a centroid (C) of the cam on the plane (X, Y) by a distance (δP), and set at a fixed position relative to the housing (1), the cam being engaged in the opening (3o).

A guide device for cannulas for the collection of micro-fragmented subcutaneous adipose tissue includes a handle which has an axial cavity intended to house a syringe equipped with a collection cannula. The axial cavity has an open proximal end, an open distal end and a central axis. A lip protrudes cantilevered from the distal end at a distance from the central axis and from said cannula. An intermediate anti-flexion element of the cannula is arranged between the handle and the lip.

The cannula (1) comprises a tube (2) with a front end (4) at which there is provided at least one suction opening (10), and with a back end (3) intended to be connected to a source of vacuum; in the tube (2) there being defined at least one longitudinal flow conduit (8, 9) for the aspirated material; and an imaging apparatus (11, 12) capable of supplying first signals or data allowing the generation of a visual representation of the environment in close proximity to the front end of the tube (2) of the cannula (1) down to a first depth or distance, and second signals or data allowing the generation of a visual representation of the environment around the front end of the tube (2) of the cannula (1) down to a second depth or distance, greater than the said first depth or distance.

Embodiments include devices and methods configured to fractionally resect skin and/or fat. Fractional resection is applied as a stand-alone procedure in anatomical areas that are off-limits to conventional plastic surgery due to the poor tradeoff between the visibility of the incisional scar and amount of enhancement obtained. Fractional resection is also applied as an adjunct to established plastic surgery procedures such as liposuction, and is employed to significantly reduce the length of incisions required for a particular application. The shortening of incisions has application in both the aesthetic and reconstructive realms of plastic surgery.

A method and apparatus that reduces the time and trauma associated with tissue removal procedures such as Ultrasound Assisted Liposuction, which emulsifies and then extracts unwanted adipose from a patient's target zone. Emulsification and suction are optimized and performed in a synchronous manner by a single apparatus to improve the outcome and minimize, if not eliminate, the limitations, risks and complications caused by current state of the art techniques.

A flexible bag for the preparation of an adipose tissue graft provided with a proximal end and a distal end and comprising: a front wall and a rear wall, which are connected to one another to define a receiving space on the inside; a first filter arranged inside the bag to divide the receiving space into a first chamber and a second chamber and to micro-fragment the adipose tissue to obtain a micro-fragmented adipose tissue; and a second filter arranged inside the second chamber to obtain a third chamber and to obtain the graft by separating a waste material from the micro-fragmented adipose tissue. The first filter comprises a distal edge which is connected to the front wall between the proximal end and the distal end and the second filter comprises a proximal edge which is connected to the rear wall between the proximal end and the distal end.

Expandable absorbable implants have been developed that are suitable for breast reconstruction following mastectomy. The implants can be implanted in the vicinity of a tissue expander, for example, by suturing to the detached edge of the pectoralis major muscle to function as a pectoralis extender, and used to form a sling for a tissue expander. The implants, which permit tissue-ingrowth and slowly degrade, can be expanded in the breast using a tissue expander in order to form a pocket for a permanent breast implant. After expansion, the tissue expander can be removed and replaced with a permanent breast implant. The expandable implants help reduce patient discomfort resulting from tissue expansion, and avoid the need to use allografts or xenografts to create the pocket for the tissue expander. The expandable absorbable implant preferably comprises poly-4-hydroxybutyrate or copolymer thereof.

Systems and methods are provided for improving efficiency and quality of plasma being removed from a blood separation chamber. The system includes a separation chamber in which plasma is separated from cellular blood components, a pump for moving the plasma and an outlet line for removing the separated plasma from the blood separation chamber. An optical sensor assembly is configured to monitor the blood separation chamber and measure an interface position between the separated component and the plasma, and to generate an output indicative of the measured interface position. A controller is programmed to utilize a lipid concentration input of the blood and to set an original lipemia offset, a lipemia threshold and lipemia final setpoint from a predetermined database, and to use a proportional-integral-derivative control loop to assess the actual interface position plus the lipemia threshold to adjust and achieve a final lipemia setpoint for use during separation procedures.

A device and associated method for centrifuging a physiological fluid includes a container including a tip, a base, and a barrel extending between the tip and the base to hold a physiological fluid. The container includes a plunger positioned within the barrel of the container. The plunger includes a concave collection surface that faces the tip of the container. A plunger gasket seal is in sealing engagement with an inside wall of the barrel of the container. A bottom support is provided to support the base of the container at least partially within the bottom support for use in a centrifuge. The container is coupled to the bottom support using an interference fit. The collection surface of the plunger and at least the barrel can be made of the same material. Advantageously, the device can be used to process blood without the need for any added anticoagulant in the blood.

Non-enzymatic method and milling device for preparing therapeutic cells from adipose tissue including continuously feeding the adipose tissue to the milling device; mechanically separating the cells or cell aggregates from adipose tissue moving through the milling device by means of a multiplicity of blades of a rotor, wherein the blades are arranged in a spaced arrangement with respect to the overall direction of flow and the blades are moving about an axis of rotation, wherein the axis of rotation is provided essentially parallel to the overall direction of flow, continuously withdrawing the processed tissue comprising the separated cells from the milling device.